Investigation of the milling characteristics of different focused-ion-beam sources assessed by three-dimensional electron diffraction from crystal lamellae

by James M. Parkhurst, Adam D. Crawshaw, C. Alistair Siebert, Maud Dumoux, C. David Owen, Pedro Nunes, David Waterman, Thomas Glen, David I. Stuart, James H. Naismith, Gwyndaf Evans
Published 2023-05-01

An in-solution snapshot of SARS-COV-2 main protease maturation process and inhibition

by Gabriela Dias Noske, Yun Song, Rafaela Sachetto Fernandes, Rod Chalk, Haitem Elmassoudi, Lizbé Koekemoer, C. David Owen, Tarick J. El-Baba, Carol V. Robinson, The COVID Moonshot Consortium, Glaucius Oliva, Andre Schutzer Godoy
Published 2023-03-01

The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif.

by Petra Lukacik, C David Owen, Gemma Harris, Jani Reddy Bolla, Sarah Picaud, Irfan Alibay, Joanne E Nettleship, Louise E Bird, Raymond J Owens, Philip C Biggin, Panagis Filippakopoulos, Carol V Robinson, Martin A Walsh
Published 2021-01-01

The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif

by Petra Lukacik, C. David Owen, Gemma Harris, Jani Reddy Bolla, Sarah Picaud, Irfan Alibay, Joanne E. Nettleship, Louise E. Bird, Raymond J. Owens, Philip C. Biggin, Panagis Filippakopoulos, Carol V. Robinson, Martin A. Walsh
Published 2021-01-01

Exploring the sequence-function space of microbial fucosidases

by Ana Martínez Gascueña, Haiyang Wu, Rui Wang, C. David Owen, Pedro J. Hernando, Serena Monaco, Matthew Penner, Ke Xing, Gwenaelle Le Gall, Richard Gardner, Didier Ndeh, Paulina A. Urbanowicz, Daniel I. R. Spencer, Martin Walsh, Jesus Angulo, Nathalie Juge
Published 2024-06-01

Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus

by C. David Owen, Louise E. Tailford, Serena Monaco, Tanja Šuligoj, Laura Vaux, Romane Lallement, Zahra Khedri, Hai Yu, Karine Lecointe, John Walshaw, Sandra Tribolo, Marc Horrex, Andrew Bell, Xi Chen, Gary L. Taylor, Ajit Varki, Jesus Angulo, Nathalie Juge
Published 2017-12-01

The human gut symbiont Ruminococcus gnavus shows specificity to blood group A antigen during mucin glycan foraging: Implication for niche colonisation in the gastrointestinal tract...

by Haiyang Wu, Emmanuelle H Crost, C David Owen, Wouter van Bakel, Ana Martínez Gascueña, Dimitrios Latousakis, Thomas Hicks, Samuel Walpole, Paulina A Urbanowicz, Didier Ndeh, Serena Monaco, Laura Sánchez Salom, Ryan Griffiths, Raven S Reynolds, Anna Colvile, Daniel I R Spencer, Martin Walsh, Jesus Angulo, Nathalie Juge
Published 2021-12-01

Publisher Correction: Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19

by Martin A. Redhead, C. David Owen, Lennart Brewitz, Amelia H. Collette, Petra Lukacik, Claire Strain-Damerell, Sean W. Robinson, Patrick M. Collins, Philipp Schäfer, Mark Swindells, Chris J. Radoux, Iva Navratilova Hopkins, Daren Fearon, Alice Douangamath, Frank von Delft, Tika R. Malla, Laura Vangeel, Thomas Vercruysse, Jan Thibaut, Pieter Leyssen, Tu-Trinh Nguyen, Mitchell Hull, Anthony Tumber, David J. Hallett, Christopher J. Schofield, David I. Stuart, Andrew L. Hopkins, Martin A. Walsh
Published 2021-09-01

Bispecific repurposed medicines targeting the viral and immunological arms of COVID-19

by Martin A. Redhead, C. David Owen, Lennart Brewitz, Amelia H. Collette, Petra Lukacik, Claire Strain-Damerell, Sean W. Robinson, Patrick M. Collins, Philipp Schäfer, Mark Swindells, Chris J. Radoux, Iva Navratilova Hopkins, Daren Fearon, Alice Douangamath, Frank von Delft, Tika R. Malla, Laura Vangeel, Thomas Vercruysse, Jan Thibaut, Pieter Leyssen, Tu-Trinh Nguyen, Mitchell Hull, Anthony Tumber, David J. Hallett, Christopher J. Schofield, David I. Stuart, Andrew L. Hopkins, Martin A. Walsh
Published 2021-06-01

Experimental phasing opportunities for macromolecular crystallography at very long wavelengths

by Kamel El Omari, Ramona Duman, Vitaliy Mykhaylyk, Christian M. Orr, Merlyn Latimer-Smith, Graeme Winter, Vinay Grama, Feng Qu, Kiran Bountra, Hok Sau Kwong, Maria Romano, Rosana I. Reis, Lutz Vogeley, Luca Vecchia, C. David Owen, Sina Wittmann, Max Renner, Miki Senda, Naohiro Matsugaki, Yoshiaki Kawano, Thomas A. Bowden, Isabel Moraes, Jonathan M. Grimes, Erika J. Mancini, Martin A. Walsh, Cristiane R. Guzzo, Raymond J. Owens, E. Yvonne Jones, David G. Brown, Dave I. Stuart, Konstantinos Beis, Armin Wagner
Published 2023-10-01

Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease

by Alice Douangamath, Daren Fearon, Paul Gehrtz, Tobias Krojer, Petra Lukacik, C. David Owen, Efrat Resnick, Claire Strain-Damerell, Anthony Aimon, Péter Ábrányi-Balogh, José Brandão-Neto, Anna Carbery, Gemma Davison, Alexandre Dias, Thomas D. Downes, Louise Dunnett, Michael Fairhead, James D. Firth, S. Paul Jones, Aaron Keeley, György M. Keserü, Hanna F. Klein, Mathew P. Martin, Martin E. M. Noble, Peter O’Brien, Ailsa Powell, Rambabu N. Reddi, Rachael Skyner, Matthew Snee, Michael J. Waring, Conor Wild, Nir London, Frank von Delft, Martin A. Walsh
Published 2020-10-01