RNA expression patterns in serum microvesicles from patients with glioblastoma multiforme and controls

by Noerholm Mikkel, Balaj Leonora, Limperg Tobias, Salehi Afshin, Zhu Lin, Hochberg Fred H, Breakefield Xandra O, Carter Bob S, Skog Johan
Published 2012-01-01

Glioblastoma-associated microglia reprogramming is mediated by functional transfer of extracellular miR-21

by Abels, Erik R., Maas, Sybren L. N., Nieland, Lisa, Wei, Zhiyun, Cheah, Pike See, Tai, Eric, Kolsteeg, Christy-Joy, Dusoswa, Sophie A., Ting, David T., Hickman, Suzanne, El Khoury, Joseph, Krichevsky, Anna M., Broekman, Marike L. D., Breakefield, Xandra O.
Published 2019

Methods for systematic identification of membrane proteins for specific capture of cancer-derived extracellular vesicles

by Zaborowsk, Mikołaj Piotr, Lee, Kyungheon, Na, Young Jeong, Sammarco, Alessandro, Zhang, Xuan, Iwanicki, Marcin, Cheah, Pike See, Lin, Hsing-Ying, Zinter, Max, Chou, Chung-Yu, Fulci, Giulia, Tannous, Bakhos A., Lai, Charles Pin-Kuang, Birrer, Michael J., Weissleder, Ralph, Lee, Hakho, Breakefield, Xandra O.
Published 2019

Glioma-derived miRNA-containing extracellular vesicles induce angiogenesis by reprogramming brain endothelial cells

by Lucero, Rocco, Zappulli, Valentina, Sammarco, Alessandro, Murillo, Oscar D, Cheah, Pike See, Srinivasan, Srimeenakshi, Tai, Eric, Ting, David T., Wei, Zhiyun, Roth, Matthew E., Laurent, Louise C., Krichevsky, Anna M., Breakefield, Xandra O, Milosavljevic, Aleksandar
Published 2020

CRISPR-Cas knockout of miR21 reduces glioma growth

by Nieland, Lisa, Solinge, Thomas S. van, Cheah, Pike See, Morsett, Liza M., Khoury, Joseph El, Rissman, Joseph I., Kleinstiver, Benjamin P., Broekman, Marike L. D., Breakefield, Xandra O., Abels, Erik R.
Published 2022

Long-term therapeutic efficacy of intravenous AAV-mediated hamartin replacement in mouse model of tuberous sclerosis type 1

by Prabhakar, Shilpa, Cheah, Pike See, Zhang, Xuan, Zinter, Max, Gianatasio, Maria, Hudry, Eloise, Bronson, Roderick T, Kwiatkowski, David J, Rachamimov, Anat Stemmer, Maguire, Casey A, Sena-Esteves, Miguel, Tannous, Bakhos A, Breakefield, Xandra O
Published 2019

Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2

by Prabhakar, Shilpa, Beauchamp, Roberta L., Cheah, Pike See, Yoshinaga, Akiko, Haidar, Edwina Abou, Lule, Sevda, Mani, Gayathri, Maalouf, Katia, Stemmer-Rachamimov, Anat, Jung, David H., Welling, D. Bradley, Giovannini, Marco, Plotkin, Scott R., Maguire, Casey A., Ramesh, Vijaya, Breakefield, Xandra O.
Published 2022

Mutant allele-specific CRISPR disruption in DYT1 dystonia fibroblasts restores cell function

by Cruz, Lilian, Bence, György, Cheah, Pike See, Kleinstiver, Benjamin P., Eimer, William A., Garcia, Sara P., Sharma, Nutan, Ozelius, Laurie J., Cristopher, Bragg D., Joung, Keith J., Norberto de Souza, Osmar, Macedo Timmers, Luis Fernando Saraiva, Breakefield, Xandra O.
Published 2020

A secreted luciferase for ex-vivo monitoring of in vivo processes

by Wurdinger, Thomas, Badr, Christian, Pike, Lisa, Kleine, Ruben de, Weissleder, Ralph, Breakefield, Xandra O., Tannous, Bakhos A.
Published 2019

Inducible Release of TRAIL Fusion Proteins from a Proapoptotic Form for Tumor Therapy

by Shah, Khalid, Tung, Ching-Hsuan, Yang, Katherine, Weissleder, Ralph, Breakefield, Xandra O.
Published 2019

Protein typing of circulating microvesicles allows real-time monitoring of glioblastoma therapy

by Shao, Huilin, Chung, Jaehoon, Balaj, Leonora, Charest, Alain, Bigner, Darell D., Carter, Bob S., Hochberg, Fred H., Breakefield, Xandra O., Weissleder, Ralph, Lee, Hakho
Published 2019

miR-296 regulates growth factor receptor overexpression in angiogenic endothelial cells

by Würdinger, Thomas, Tannous, Bakhos A., Saydam, Okay, Skog, Johan, Grau, Stephan, Soutschek, Jürgen, Weissleder, Ralph, Breakefield, Xandra O., Krichevsky, Anna M.
Published 2019

Mutant Sodium Channel for Tumor Therapy

by Tannous, Bakhos A., Christensen, Adam P., Pike, Lisa, Wurdinger, Thomas, Perry, Katherine F., Saydam, Okay, Jacobs, Andreas H., García-Añoveros, Jaime, Weissleder, Ralph, Sena-Esteves, Miguel, Corey, David P., Breakefield, Xandra O.
Published 2019

Heparin affinity purification of extracellular vesicles

by Balaj, Leonora, Atai, Nadia A., Chen, Weilin, Mu, Dakai, Tannous, Bakhos A., Breakefield, Xandra O., Skog, Johan, Maguire, Casey A.
Published 2015

Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma

by Shao, Huilin, Chung, Jaehoon, Lee, Kyungheon, Balaj, Leonora, Min, Changwook, Carter, Bob S., Hochberg, Fred H., Breakefield, Xandra O., Lee, Hakho, Weissleder, Ralph
Published 2015

Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles

by Reátegui, Eduardo, van der Vos, Kristan E., Lai, Charles P., Zeinali, Mahnaz, Atai, Nadia A., Aldikacti, Berent, Floyd, Frederick P., H. Khankhel, Aimal, Thapar, Vishal, Hochberg, Fred H., Sequist, Lecia V., Nahed, Brian V., S. Carter, Bob, Toner, Mehmet, Balaj, Leonora, T. Ting, David, Breakefield, Xandra O., Stott, Shannon L.
Published 2018

Coding and noncoding landscape of extracellular RNA released by human glioma stem cells

by Wei, Zhiyun, Batagov, Arsen O., Schinelli, Sergio, Wang, Jintu, Wang, Yang, El Fatimy, Rachid, Rabinovsky, Rosalia, Balaj, Leonora, Chen, Clark C., Hochberg, Fred, Carter, Bob, Breakefield, Xandra O., Krichevsky, Anna M.
Published 2017

Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters

by Lai, Charles P., Kim, Edward Y., Badr, Christian E., Weissleder, Ralph, Mempel, Thorsten R., Tannous, Bakhos A., Breakefield, Xandra O.
Published 2015

A Novel Method for Imaging Apoptosis Using a Caspase-1 Near-Infrared Fluorescent Probe

by Messerli, Shanta M., Prabhakar, Shilpa, Tang, Yi, Shah, Khalid, Cortes, Maria L., Murthy, Vidya, Weissleder, Ralph, Breakefield, Xandra O., Tung, Ching-Hsuan
Published 2019

Codon-Optimized Gaussia Luciferase cDNA for Mammalian Gene Expression in Culture and in Vivo

by Tannous, Bakhos A., Kim, Dong-Eog, Fernandez, Juliet L., Weissleder, Ralph, Breakefield, Xandra O.
Published 2019