Elongator and the role of its subcomplexes in human diseases

by Monika Gaik, Marija Kojic, Brandon J Wainwright, Sebastian Glatt
Published 2023-02-01

Genetic and functional interaction network analysis reveals global enrichment of regulatory T cell genes influencing basal cell carcinoma susceptibility

by Christelle Adolphe, Angli Xue, Atefeh Taherian Fard, Laura A. Genovesi, Jian Yang, Brandon J. Wainwright
Published 2021-02-01

Editorial: Bench to bedside: translating pre-clinical research into clinical trials for childhood brain tumors

by Raelene Endersby, Raelene Endersby, Brandon J. Wainwright, Nicholas G. Gottardo, Nicholas G. Gottardo, Nicholas G. Gottardo
Published 2023-08-01

Proliferation of murine midbrain neural stem cells depends upon an endogenous sonic hedgehog (Shh) source.

by Constanza Martínez, Víctor Hugo Cornejo, Pablo Lois, Tammy Ellis, Natalia P Solis, Brandon J Wainwright, Verónica Palma
Published 2013-01-01

Correction: Proliferation of Murine Midbrain Neural Stem Cells Depends upon an Endogenous Sonic Hedgehog (Shh) Source.

by Constanza Martínez, Víctor Hugo Cornejo, Pablo Lois, Tammy Ellis, Natalia P Solis, Brandon J Wainwright, Verónica Palma
Published 2020-01-01

Sonic hedgehog and notch signaling can cooperate to regulate neurogenic divisions of neocortical progenitors.

by Richa K Dave, Tammy Ellis, Melissa C Toumpas, Jonathan P Robson, Elaine Julian, Christelle Adolphe, Perry F Bartlett, Helen M Cooper, Brent A Reynolds, Brandon J Wainwright
Published 2011-02-01

Spatial transcriptomic analysis of Sonic hedgehog medulloblastoma identifies that the loss of heterogeneity and promotion of differentiation underlies the response to CDK4/6 inhibi...

by Tuan Vo, Brad Balderson, Kahli Jones, Guiyan Ni, Joanna Crawford, Amanda Millar, Elissa Tolson, Matthew Singleton, Marija Kojic, Thomas Robertson, Shaun Walters, Onkar Mulay, Dharmesh D. Bhuva, Melissa J. Davis, Brandon J. Wainwright, Quan Nguyen, Laura A. Genovesi
Published 2023-05-01

Elongator mutation in mice induces neurodegeneration and ataxia-like behavior

by Marija Kojic, Monika Gaik, Bence Kiska, Anna Salerno-Kochan, Sarah Hunt, Angelo Tedoldi, Sergey Mureev, Alun Jones, Belinda Whittle, Laura A. Genovesi, Christelle Adolphe, Darren L. Brown, Jennifer L. Stow, Kirill Alexandrov, Pankaj Sah, Sebastian Glatt, Brandon J. Wainwright
Published 2018-08-01

Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma

by Laura A. Genovesi, Amanda Millar, Elissa Tolson, Matthew Singleton, Emily Hassall, Marija Kojic, Caterina Brighi, Emily Girard, Clara Andradas, Mani Kuchibhotla, Dharmesh D. Bhuva, Raelene Endersby, Nicholas G. Gottardo, Anne Bernard, Christelle Adolphe, James M. Olson, Michael D. Taylor, Melissa J. Davis, Brandon J. Wainwright
Published 2021-06-01

Functional divergence of the two Elongator subcomplexes during neurodevelopment

by Monika Gaik, Marija Kojic, Megan R Stegeman, Tülay Öncü‐Öner, Anna Kościelniak, Alun Jones, Ahmed Mohamed, Pak Yan Stefanie Chau, Sazia Sharmin, Andrzej Chramiec‐Głąbik, Paulina Indyka, Michał Rawski, Anna Biela, Dominika Dobosz, Amanda Millar, Vann Chau, Aycan Ünalp, Michael Piper, Mark C Bellingham, Evan E Eichler, Deborah A Nickerson, Handan Güleryüz, Nour El Hana Abbassi, Konrad Jazgar, Melissa J Davis, Saadet Mercimek‐Andrews, Sultan Cingöz, Brandon J Wainwright, Sebastian Glatt
Published 2022-07-01

Elp2 mutations perturb the epitranscriptome and lead to a complex neurodevelopmental phenotype

by Marija Kojic, Tomasz Gawda, Monika Gaik, Alexander Begg, Anna Salerno-Kochan, Nyoman D. Kurniawan, Alun Jones, Katarzyna Drożdżyk, Anna Kościelniak, Andrzej Chramiec-Głąbik, Soroor Hediyeh-Zadeh, Maria Kasherman, Woo Jun Shim, Enakshi Sinniah, Laura A. Genovesi, Rannvá K. Abrahamsen, Christina D. Fenger, Camilla G. Madsen, Julie S. Cohen, Ali Fatemi, Zornitza Stark, Sebastian Lunke, Joy Lee, Jonas K. Hansen, Martin F. Boxill, Boris Keren, Isabelle Marey, Margarita S. Saenz, Kathleen Brown, Suzanne A. Alexander, Sergey Mureev, Alina Batzilla, Melissa J. Davis, Michael Piper, Mikael Bodén, Thomas H. J. Burne, Nathan J. Palpant, Rikke S. Møller, Sebastian Glatt, Brandon J. Wainwright
Published 2021-05-01