The apolipoprotein E polymorphism: A comparison of allele frequencies and effects in nine populations

by Hallman, D.M., Boerwinkle, E., Saha, N., Sandholzer, C., Menzel, H.J., Csázár, A., Utermann, G.
Published 2016

Apo(a) isoforms predict risk for coronary heart disease - A study in six populations

by Sandholzer, C., Saha, N., Kark, J.D., Rees, A., Jaross, W., Dieplinger, H., Hoppichler, F., Boerwinkle, E., Utermann, G.
Published 2016

Apolipoprotein(a) phenotypes, Lp(a) concentration and plasma lipid levels in relation to coronary heart disease in a chinese population: Evidence for the role of the apo(a) gene in...

by Sandholzer, Ch., Boerwinkle, E., Saha, N., Tong, M.C., Utermann, G.
Published 2016

Admixture mapping scans identify a locus affecting retinal vascular caliber in hypertensive African Americans: The Atherosclerosis Risk in Communities (ARIC) study

by Cheng C.-Y., Reich D., Wong T.Y., Klein R., Klein B.E.K., Patterson N., Tandon A., Li M., Boerwinkle E., Richey Sharrett A., Linda Kao W.H.
Published 2018

African ancestry and its correlation to type 2 diabetes in african americans: A genetic admixture analysis in three U.S. population cohorts

by Cheng, C.-Y., Reich, D., Haiman, C.A., Tandon, A., Patterson, N., Elizabeth, S., Akylbekova, E.L., Brancati, F.L., Coresh, J., Boerwinkle, E., Altshuler, D., Taylor, H.A., Henderson, B.E., Wilson, J.G., Kao, W.H.
Published 2014

Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene

by Reich D., Nalls M.A., Kao W.H.L., Akylbekova E.L., Tandon A., Patterson N., Mullikin J., Hsueh W.-C., Cheng C.-Y., Coresh J., Boerwinkle E., Li M., Waliszewska A., Neubauer J., Li R., Leak T.S., Ekunwe L., Files J.C., Hardy C.L., Zmuda J.M., Taylor H.A., Ziv E., Harris T.B., Wilson J.G.
Published 2018

Are C-Reactive Protein Associated Genetic Variants Associated with Serum Levels and Retinal Markers of Microvascular Pathology in Asian Populations from Singapore?

by Dorajoo, R., Li, R., Ikram, M.K., Liu, J., Froguel, P., Lee, J., Sim, X., Ong, R.T.-H., Tay, W.T., Peng, C., Young, T.L., Blakemore, A.I.F., Cheng, C.Y., Aung, T., Mitchell, P., Wang, J.J., Klaver, C.C., Boerwinkle, E., Klein, R., Siscovick, D.S., Jensen, R.A., Gudnason, V., Smith, A.V., Teo, Y.Y., Wong, T.Y., Tai, E.-S., Heng, C.-K., Friedlander, Y.
Published 2014

Genome-wide meta-analysis identifies regions on 7p21 (AHR) and 15q24 (CYP1A2) as determinants of habitual caffeine consumption

by Cornelis, M.C., Monda, K.L., Yu, K., Paynter, N., Azzato, E.M., Bennett, S.N., Berndt, S.I., Boerwinkle, E., Chanock, S., Chatterjee, N., Couper, D., Curhan, G., Heiss, G., Hu, F.B., Hunter, D.J., Jacobs, K., Jensen, M.K., Kraft, P., Landi, M.T., Nettleton, J.A., Purdue, M.P., Rajaraman, P., Rimm, E.B., Rose, L.M., Rothman, N., Silverman, D., Stolzenberg-Solomon, R., Subar, A., Yeager, M., Chasman, D.I., van Dam, R.M., Caporaso, N.E.
Published 2014

Associations of NINJ2 sequence variants with incident ischemic stroke in the Cohorts for Heart and Aging in Genomic Epidemiology (CHARGE) consortium

by Bis J.C., DeStefano A., Liu X., Brody J.A., Choi S.H., Verhaaren B.F.J., Debette S., Ikram M.A., Shahar E., Butler Jr. K.R., Gottesman R.F., Muzny D., Kovar C.L., Psaty B.M., Hofman A., Lumley T., Gupta M., Wolf P.A., Van Duijn C., Gibbs R.A., Mosley T.H., Longstreth Jr. W.T., Boerwinkle E., Seshadri S., Fornage M.
Published 2019

Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis

by Holliday, E.G., Smith, A.V., Cornes, B.K., Buitendijk, G.H.S., Jensen, R.A., Sim, X., Aspelund, T., Aung, T., Baird, P.N., Boerwinkle, E., Cheng, C.Y., van Duijn, C.M., Eiriksdottir, G., Gudnason, V., Harris, T., Hewitt, A.W., Inouye, M., Jonasson, F., Klein, B.E.K., Launer, L., Li, X., Liew, G., Lumley, T., McElduff, P., McKnight, B., Mitchell, P., Psaty, B.M., Rochtchina, E., Rotter, J.I., Scott, R.J., Tay, W., Taylor, K., Teo, Y.Y., Uitterlinden, A.G., Viswanathan, A., Xie, S., Vingerling, J.R., Klaver, C.C.W., Tai, E.S., Siscovick, D., Klein, R., Cotch, M.F., Wong, T.Y., Attia, J., Wang, J.J.
Published 2014

Genome-Wide Association Study of Retinopathy in Individuals without Diabetes

by Jensen, R.A., Sim, X., Li, X., Cotch, M.F., Ikram, M.K., Holliday, E.G., Eiriksdottir, G., Harris, T.B., Jonasson, F., Klein, B.E.K., Launer, L.J., Smith, A.V., Boerwinkle, E., Cheung, N., Hewitt, A.W., Liew, G., Mitchell, P., Wang, J.J., Attia, J., Scott, R., Glazer, N.L., Lumley, T., McKnight, B., Psaty, B.M., Taylor, K., Hofman, A., de Jong, P.T.V.M., Rivadeneira, F., Uitterlinden, A.G., Tay, W.-T., Teo, Y.Y., Seielstad, M., Liu, J., Cheng, C.-Y., Saw, S.-M., Aung, T., Ganesh, S.K., O'Donnell, C.J., Nalls, M.A., Wiggins, K.L., Kuo, J.Z., van Duijn, C.M., Gudnason, V., Klein, R., Siscovick, D.S., Rotter, J.I., Tai, E.S., Vingerling, J., Wong, T.Y.
Published 2014

Genetic Loci for Retinal Arteriolar Microcirculation

by Sim, X., Jensen, R.A., Ikram, M.K., Cotch, M.F., Li, X., MacGregor, S., Xie, J., Smith, A.V., Boerwinkle, E., Mitchell, P., Klein, R., Klein, B.E.K., Glazer, N.L., Lumley, T., McKnight, B., Psaty, B.M., de Jong, P.T.V.M., Hofman, A., Rivadeneira, F., Uitterlinden, A.G., van Duijn, C.M., Aspelund, T., Eiriksdottir, G., Harris, T.B., Jonasson, F., Launer, L.J., Attia, J., Baird, P.N., Harrap, S., Holliday, E.G., Inouye, M., Rochtchina, E., Scott, R.J., Viswanathan, A., Li, G., Smith, N.L., Wiggins, K.L., Kuo, J.Z., Taylor, K.D., Hewitt, A.W., Martin, N.G., Montgomery, G.W., Sun, C., Young, T.L., Mackey, D.A., van Zuydam, N.R., Doney, A.S.F., Palmer, C.N.A., Morris, A.D., Rotter, J.I., Tai, E.S., Gudnason, V., Vingerling, J.R., Siscovick, D.S., Wang, J.J., Wong, T.Y.
Published 2014

Four novel loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation In vivo

by Kamran Ikram, M., Xueling, S., Jensen, R.A., Cotch, M.F., Hewitt, A.W., Ikram, M.A., Wang, J.J., Klein, R., Klein, B.E.K., Breteler, M.M.B., Cheung, N., Liew, G., Mitchell, P., Uitterlinden, A.G., Rivadeneira, F., Hofman, A., de Jong, P.T.V.M., van Duijn, C.M., Kao, L., Cheng, C.-Y., Smith, A.V., Glazer, N.L., Lumley, T., McKnight, B., Psaty, B.M., Jonasson, F., Eiriksdottir, G., Aspelund, T., Harris, T.B., Launer, L.J., Taylor, K.D., Li, X., Iyengar, S.K., Xi, Q., Sivakumaran, T.A., MacKey, D.A., MacGregor, S., Martin, N.G., Young, T.L., Bis, J.C., Wiggins, K.L., Heckbert, S.R., Hammond, C.J., Andrew, T., Fahy, S., Attia, J., Holliday, E.G., Scott, R.J., Islam, F.M.A., Rotter, J.I., McAuley, A.K., Boerwinkle, E., Tai, E.S., Gudnason, V., Siscovick, D.S., Vingerling, J.R., Wong, T.Y.
Published 2014

The Alzheimer's Disease Sequencing Project: Study design and sample selection

by Beecham, Gary W., Bis, J.C., Martin, E.R., Choi, S.-H., DeStefano, A. L., van Duijn, C.M., Fornage, M., Gabriel, S.B., Koboldt, D.C., Larson, D.E., Naj, A.C., Psaty, B.M., Salerno, W., Bush, W.S., Foroud, T.M., Wijsman, E., Farrer, L.A., Goate, A., Haines, J.L., Pericak-Vance, Margaret A., Boerwinkle, E., Mayeux, R., Seshadri, S., Schellenberg, G.
Published 2017

A genome-wide association study identifies new loci for factor VII and implicates factor VII in ischemic stroke etiology

by Vries, P.S. de, Sabater-Lleal, M., Huffman, J.E., Marten, J., Song, C., Pankratz, N., Bartz, T.M., Haan, H.G. de, Delgado, G.E., Eicher, J.D., Martinez-Perez, A., Ward-Caviness, C.K., Brody, J.A., Chen, M.H., Maat, M.P.M. de, Franberg, M., Gill, D., Kleber, M.E., Rivadeneira, F., Soria, J.M., Tang, W.H., Tofler, G.H., Uitterlinden, A.G., Vlieg, A.V., Seshadri, S., Boerwinkle, E., Davies, N.M., Giese, A.K., Ikram, M.K., Kittner, S.J., McKnight, B., Psaty, B.M., Reiner, A.P., Sargurupremraj, M., Taylor, K.D., Fornage, M., Hamsten, A., Marz, W., Rosendaal, F.R., Souto, J.C., Dehghan, A., Johnson, A.D., Morrison, A.C., O'Donnell, C.J., Smith, N.L., INVENT Consortium, MEGASTROKE Consortium Intl
Published 2019

Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium

by Bis, J.C., Sitlani, C., Irvin, R., Avery, C.L., Smith, A.V., Sun, F.G., Evans, D.S., Musani, S.K., Li, X.H., Trompet, S., Krijthe, B.P., Harris, T.B., Quibrera, P.M., Brody, J.A., Demissie, S., Davis, B.R., Wiggins, K.L., Tranah, G.J., Lange, L.A., Sotoodehnia, N., Stott, D.J., Franco, O.H., Launer, L.J., Sturmer, T., Taylor, K.D., Cupples, L.A., Eckfeldt, J.H., Smith, N.L., Liu, Y.M., Wilson, J.G., Heckbert, S.R., Buckley, B.M., Ikram, M.A., Boerwinkle, E., Chen, Y.D.I., Craen, A.J.M. de, Uitterlinden, A.G., Rotter, J.I., Ford, I., Hofman, A., Sattar, N., Slagboom, P.E., Westendorp, R.G.J., Gudnason, V., Vasan, R.S., Lumley, T., Cummings, S.R., Taylor, H.A., Post, W., Jukema, J.W., Stricker, B.H., Whitsel, E.A., Psaty, B.M., Arnett, D.
Published 2015

Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure

by Smith, J.G., Felix, J.F., Morrison, A.C., Kalogeropoulos, A., Trompet, S., Wilk, J.B., Gidlof, O., Wang, X.C., Morley, M., Mendelson, M., Joehanes, R., Ligthart, S., Shan, X.Y., Bis, J.C., Wang, Y.A., Sjogren, M., Ngwa, J., Brandimarto, J., Stott, D.J., Aguilar, D., Rice, K.M., Sesso, H.D., Demissie, S., Buckley, B.M., Taylor, K.D., Ford, I., Yao, C., Liu, C.Y., Sotoodehnia, N., Harst, P. van der, Stricker, B.H.C., Kritchevsky, S.B., Liu, Y.M., Gaziano, J.M., Hofman, A., Moravec, C.S., Uitterlinden, A.G., Kellis, M., Meurs, J.B. van, Margulies, K.B., Dehghan, A., Levy, D., Olde, B., Psaty, B.M., Cupples, L.A., Jukema, J.W., Djousse, L., Franco, O.H., Boerwinkle, E., Boyer, L.A., Newton-Cheh, C., Butler, J., Vasan, R.S., Cappola, T.P., Smith, N.L., CHARGE-SCD Consortium, EchoGen Consortium, QT-IGC Consortium, CHARGE-QRS Consortium
Published 2016

Whole-Exome Sequencing Identifies Loci Associated with Blood Cell Traits and Reveals a Role for Alternative GFI1B Splice Variants in Human Hematopoiesis

by Polfus, L.M., Khajuria, R.K., Schick, U.M., Pankratz, N., Pazoki, R., Brody, J.A., Chen, M.H., Auer, P.L., Floyd, J.S., Huang, J., Lange, L., Rooij, F.J.A. van, Gibbs, R.A., Metcalf, G., Muzny, D., Veeraraghavan, N., Walter, K., Chen, L., Yanek, L., Becker, L.C., Peloso, G.M., Wakabayashi, A., Kals, M., Metspalu, A., Esko, T., Fox, K., Wallace, R., Franceschini, N., Matijevic, N., Rice, K.M., Bartz, T.M., Lyytikainen, L.P., Kahonen, M., Lehtimaki, T., Raitakari, O.T., Li-Gao, R., Mook-Kanamori, D.O., Lettre, G., Duijn, C.M. van, Franco, O.H., Rich, S.S., Rivadeneira, F., Hofman, A., Uitterlinden, A.G., Wilson, J.G., Psaty, B.M., Soranzo, N., Dehghan, A., Boerwinkle, E., Zhang, X.L., Johnson, A.D., O'Donnell, C.J., Johnsen, J.M., Reiner, A.P., Ganesh, S.K., Sankaran, V.G.
Published 2016

Genetic Loci for Retinal Arteriolar Microcirculation

by Sim, X., Jensen, R.A., Ikram, M.K., Cotch, M.F., Li, X.H., MacGregor, S., Xie, J., Smith, A.V., Boerwinkle, E., Mitchell, P., Klein, R., Klein, B.E.K., Glazer, N.L., Lumley, T., McKnight, B., Psaty, B.M., Jong, P.T.V.M. de, Hofman, A., Rivadeneira, F., Uitterlinden, A.G., Duijn, C.M. van, Aspelund, T., Eiriksdottir, G., Harris, T.B., Jonasson, F., Launer, L.J., Attia, J., Baird, P.N., Harrap, S., Holliday, E.G., Inouye, M., Rochtchina, E., Scott, R.J., Viswanathan, A., Li, G., Smith, N.L., Wiggins, K.L., Kuo, J.Z., Taylor, K.D., Hewitt, A.W., Martin, N.G., Montgomery, G.W., Sun, C., Young, T.L., Mackey, D.A., Zuydam, N.R. van, Doney, A.S.F., Palmer, C.N.A., Morris, A.D., Rotter, J.I., Tai, E.S., Gudnason, V., Vingerling, J.R., Siscovick, D.S., Wang, J.J., Wong, T.Y., Wellcome Trust Case Control Consor, Global BPGen Consortium
Published 2013

Drug-gene interactions and the search for missing heritability: a cross-sectional pharmacogenomics study of the QT interval

by Avery, C.L., Sitlani, C.M., Arking, D.E., Arnett, D.K., Bis, J.C., Boerwinkle, E., Buckley, B.M., Chen, Y.D.I., Craen, A.J.M. de, Eijgelsheim, M., Enquobahrie, D., Evans, D.S., Ford, I., Garcia, M.E., Gudnason, V., Harris, T.B., Heckbert, S.R., Hochner, H., Hofman, A., Hsueh, W.C., Isaacs, A., Jukema, J.W., Knekt, P., Kors, J.A., Krijthe, B.P., Kristiansson, K., Laaksonen, M., Liu, Y., Li, X., MacFarlane, P.W., Newton-Cheh, C., Nieminen, M.S., Oostra, B.A., Peloso, G.M., Porthan, K., Rice, K., Rivadeneira, F.F., Rotter, J.I., Salomaa, V., Sattar, N., Siscovick, D.S., Slagboom, P.E., Smith, A.V., Sotoodehnia, N., Stott, D.J., Stricker, B.H., Sturmer, T., Trompet, S., Uitterlinden, A.G., Duijn, C. van, Westendorp, R.G.J., Witteman, J.C., Whitsel, E.A., Psaty, B.M.
Published 2014