173 An in vivo CRISPR/Cas9 screening platform to identify T cell enhancing edits in distinct solid tumor microenvironments

by Jeff Jones, Amy Becker, Troy Luster, Ishina Balwani, Nachiket Shevale, Jingwei Sun, Erica Del Aguila, Srijani Sridhar, Nishit Patel, Daniel O’Connell, Reynald Lescarbeau, Birgit Schultes
Published 2020-11-01

342 Improving TCR-T cell function against solid tumors with immune enhancing edits

by Amy Becker, Troy Luster, Ishina Balwani, Erica Del Aguila, Nishit Patel, Birgit Schultes, Justin Oh, Nachiket Narendra Shevale, Ivy Dutta, Nazia Ali, Nithila Saravanan, James Peter, Yurui Guo, Hanan Dahche, Jingyu Peng, Bo Han, Dai Liu, Aaron Prodeus, Michael Lam
Published 2023-11-01

M402, a novel heparan sulfate mimetic, targets multiple pathways implicated in tumor progression and metastasis.

by He Zhou, Sucharita Roy, Edward Cochran, Radouane Zouaoui, Chia Lin Chu, Jay Duffner, Ganlin Zhao, Sean Smith, Zoya Galcheva-Gargova, Juliane Karlgren, Nancy Dussault, Rain Y Q Kwan, Erick Moy, Marishka Barnes, Alison Long, Chris Honan, Yi Wei Qi, Zachary Shriver, Tanmoy Ganguly, Birgit Schultes, Ganesh Venkataraman, Takashi Kei Kishimoto
Published 2011-01-01

Epithelial ovarian cancer is infiltrated by activated effector T cells co-expressing CD39, PD-1, TIM-3, CD137 and interacting with cancer cells and myeloid cells

by Elena Tassi, Elena Tassi, Alice Bergamini, Alice Bergamini, Jessica Wignall, Miriam Sant’Angelo, Emanuela Brunetto, Chiara Balestrieri, Miriam Redegalli, Alessia Potenza, Danilo Abbati, Francesco Manfredi, Francesco Manfredi, Maria Giulia Cangi, Gilda Magliacane, Fabiola Scalisi, Eliana Ruggiero, Maria Chiara Maffia, Federica Trippitelli, Emanuela Rabaiotti, Raffaella Cioffi, Luca Bocciolone, Giorgio Candotti, Massimo Candiani, Massimo Candiani, Gianluca Taccagni, Birgit Schultes, Claudio Doglioni, Claudio Doglioni, Giorgia Mangili, Chiara Bonini, Chiara Bonini, Chiara Bonini
Published 2023-10-01