Editorial: Genomic imprinting and monoallelic gene expression mechanisms and applications

by Maria Oczkowicz, Benjamin Tycko, Julie Demars
Published 2022-11-01

Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome

by Xu-Qiao Chen, Zhuo Xing, Quang-Di Chen, Richard J. Salvi, Xuming Zhang, Benjamin Tycko, Benjamin Tycko, William C. Mobley, Y. Eugene Yu, Y. Eugene Yu
Published 2021-07-01

A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigen...

by Ahrim Youn, Kyung In Kim, Raul Rabadan, Benjamin Tycko, Yufeng Shen, Shuang Wang
Published 2018-11-01

Genetic–epigenetic interactions in cis: a major focus in the post-GWAS era

by Catherine Do, Alyssa Shearer, Masako Suzuki, Mary Beth Terry, Joel Gelernter, John M. Greally, Benjamin Tycko
Published 2017-06-01

A common Hpa I RFLP of apolipoprotein C-I increases gene transcription and exhibits an ethnically distinct pattern of linkage disequilibrium with the alleles of apolipoprotein E

by Yan Xu, Lars Berglund, Rajasekhar Ramakrishnan, Richard Mayeux, Colleen Ngai, Steven Holleran, Benjamin Tycko, Todd Leff, Neil S. Shachter
Published 1999-01-01

Epigenetic Alterations Affecting Transcription Factors and Signaling Pathways in Stromal Cells of Endometriosis.

by Iveta Yotova, Emily Hsu, Catherine Do, Aulona Gaba, Matthias Sczabolcs, Sabine Dekan, Lukas Kenner, Rene Wenzl, Benjamin Tycko
Published 2017-01-01

Stress and DNA Methylation of Blood Leukocytes among Pregnant Latina Women

by Veronica Barcelona, Sameera Abuaish, Seonjoo Lee, Sarah Harkins, Ashlie Butler, Benjamin Tycko, Andrea A. Baccarelli, Kate Walsh, Catherine E. Monk
Published 2023-11-01

Stromal protein Ecm1 regulates ureteric bud patterning and branching.

by Suneeta S Paroly, Fengwei Wang, Lee Spraggon, Joseph Merregaert, Ekatherina Batourina, Benjamin Tycko, Kai M Schmidt-Ott, Sean Grimmond, Melissa Little, Cathy Mendelsohn
Published 2013-01-01

Polymorphisms in HSD17B1: Early Onset and Increased Risk of Alzheimer’s Disease in Women with Down Syndrome

by Joseph H. Lee, Susan Gurney, Deborah Pang, Alexis Temkin, Naeun Park, Sarah C. Janicki, Warren B. Zigman, Wayne Silverman, Benjamin Tycko, Nicole Schupf
Published 2012-01-01

DNA methylation patterns in T lymphocytes are generally stable in human pregnancies but CD3 methylation is associated with perinatal psychiatric symptoms

by Thalia K. Robakis, Seonjoo Lee, Elizabeth Werner, Grace Liu, Melissa Miller, Dennis Wylie, Frances A. Champagne, Martha Salas, Catherine Do, Benjamin Tycko, Catherine Monk
Published 2020-03-01

The Association between Sex and Risk of Alzheimer’s Disease in Adults with Down Syndrome

by Pooja Girish Mhatre, Joseph H. Lee, Deborah Pang, Warren B. Zigman, Benjamin Tycko, Sharon J. Krinsky-McHale, Yuchen Yang, Wayne Silverman, Nicole Schupf
Published 2021-07-01

A Pathologic Link between Wilms Tumor Suppressor Gene, WT1, and IFI16

by Marianne K-H. Kim, Jacqueline M. Mason, Chi-Ming Li, Windy Berkofsky-Fessler, Le Jiang, Divaker Choubey, Paul E. Grundy, Benjamin Tycko, Jonathan D. Licht
Published 2008-01-01

Prodromal Alzheimer's disease can affect activities of daily living for adults with Down syndrome

by Tracy A. Listwan, Sharon J. Krinsky‐McHale, Cynthia M. Kovacs, Joseph H. Lee, Deborah I. Pang, Nicole Schupf, Benjamin Tycko, Warren B. Zigman, Wayne Silverman
Published 2024-01-01

Genome-wide divergence of DNA methylation marks in cerebral and cerebellar cortices.

by Yurong Xin, Benjamin Chanrion, Meng-Min Liu, Hanga Galfalvy, Ramiro Costa, Boro Ilievski, Gorazd Rosoklija, Victoria Arango, Andrew J Dwork, J John Mann, Benjamin Tycko, Fatemeh Haghighi
Published 2010-06-01

Altered DNA methylation in leukocytes with trisomy 21.

by Kristi Kerkel, Nicole Schupf, Kota Hatta, Deborah Pang, Martha Salas, Alexander Kratz, Mark Minden, Vundavalli Murty, Warren B Zigman, Richard P Mayeux, Edmund C Jenkins, Ali Torkamani, Nicholas J Schork, Wayne Silverman, B Anne Croy, Benjamin Tycko
Published 2010-11-01

Comparative anatomy of chromosomal domains with imprinted and non-imprinted allele-specific DNA methylation.

by Anupam Paliwal, Alexis M Temkin, Kristi Kerkel, Alexander Yale, Iveta Yotova, Natalia Drost, Simon Lax, Chia-Ling Nhan-Chang, Charles Powell, Alain Borczuk, Abraham Aviv, Ronald Wapner, Xiaowei Chen, Peter L Nagy, Nicholas Schork, Catherine Do, Ali Torkamani, Benjamin Tycko
Published 2013-08-01

Breast cancer family history and allele-specific DNA methylation in the legacy girls study

by Hui-Chen Wu, Catherine Do, Irene L. Andrulis, Esther M. John, Mary B. Daly, Saundra S Buys, Wendy K. Chung, Julia A. Knight, Angela R. Bradbury, Theresa H. M. Keegan, Lisa Schwartz, Izabela Krupska, Rachel L. Miller, Regina M. Santella, Benjamin Tycko, Mary Beth Terry
Published 2018-03-01

NPTX2 and cognitive dysfunction in Alzheimer’s Disease

by Mei-Fang Xiao, Desheng Xu, Michael T Craig, Kenneth A Pelkey, Chun-Che Chien, Yang Shi, Juhong Zhang, Susan Resnick, Olga Pletnikova, David Salmon, James Brewer, Steven Edland, Jerzy Wegiel, Benjamin Tycko, Alena Savonenko, Roger H Reeves, Juan C Troncoso, Chris J McBain, Douglas Galasko, Paul F Worley
Published 2017-03-01

Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs

by Catherine Do, Emmanuel L. P. Dumont, Martha Salas, Angelica Castano, Huthayfa Mujahed, Leonel Maldonado, Arunjot Singh, Sonia C. DaSilva-Arnold, Govind Bhagat, Soren Lehman, Angela M. Christiano, Subha Madhavan, Peter L. Nagy, Peter H. R. Green, Rena Feinman, Cornelia Trimble, Nicholas P. Illsley, Karen Marder, Lawrence Honig, Catherine Monk, Andre Goy, Kar Chow, Samuel Goldlust, George Kaptain, David Siegel, Benjamin Tycko
Published 2020-06-01

Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium–Down Syndrom...

by Melissa E. Petersen, Fan Zhang, Nicole Schupf, Sharon J. Krinsky‐McHale, James Hall, Mark Mapstone, Amrita Cheema, Wayne Silverman, Ira Lott, Michael S. Rafii, Benjamin Handen, William Klunk, Elizabeth Head, Brad Christian, Tatiana Foroud, Florence Lai, H. Diana Rosas, Shahid Zaman, Beau M. Ances, Mei‐Cheng Wang, Benjamin Tycko, Joseph H. Lee, Sid O'Bryant, the Alzheimer's Biomarker Consortium – Down Syndrome (ABC‐DS)
Published 2020-01-01