A Hyper-Attenuated Variant of Rift Valley Fever Virus Generated by a Mutagenic Drug (Favipiravir) Unveils Potential Virulence Markers

by Belén Borrego, Alejandro Brun
Published 2021-02-01

The Change P82L in the Rift Valley Fever Virus NSs Protein Confers Attenuation in Mice

by Belén Borrego, Sandra Moreno, Nuria de la Losa, Friedemann Weber, Alejandro Brun
Published 2021-03-01

MVA Vectored Vaccines Encoding Rift Valley Fever Virus Glycoproteins Protect Mice against Lethal Challenge in the Absence of Neutralizing Antibody Responses

by Elena López-Gil, Sandra Moreno, Javier Ortego, Belén Borrego, Gema Lorenzo, Alejandro Brun
Published 2020-02-01

Synthetic RNAs Mimicking Structural Domains in the Foot-and-Mouth Disease Virus Genome Elicit a Broad Innate Immune Response in Porcine Cells Triggered by RIG-I and TLR Activation

by Belén Borrego, Miguel Rodríguez-Pulido, Concepción Revilla, Belén Álvarez, Francisco Sobrino, Javier Domínguez, Margarita Sáiz
Published 2015-07-01

Identification of Single Amino Acid Changes in the Rift Valley Fever Virus Polymerase Core Domain Contributing to Virus Attenuation In Vivo

by Belén Borrego, Sandra Moreno, Álvaro López-Valiñas, Nuria de la Losa, Friedemann Weber, José Ignacio Núñez, Alejandro Brun
Published 2022-04-01

A single immunization with MVA expressing GnGc glycoproteins promotes epitope-specific CD8+-T cell activation and protects immune-competent mice against a lethal RVFV infection.

by Elena López-Gil, Gema Lorenzo, Esther Hevia, Belén Borrego, Martin Eiden, Martin Groschup, Sarah C Gilbert, Alejandro Brun
Published 2013-01-01

Precise location of linear epitopes on the capsid surface of feline calicivirus recognized by neutralizing and non-neutralizing monoclonal antibodies

by Carolina Cubillos-Zapata, Iván Angulo, Horacio Almanza, Belén Borrego, María Zamora-Ceballos, José R. Castón, Ignacio Mena, Esther Blanco, Juan Bárcena
Published 2020-05-01

Protection against West Nile virus infection in mice after inoculation with type I interferon-inducing RNA transcripts.

by Miguel Rodríguez-Pulido, Miguel A Martín-Acebes, Estela Escribano-Romero, Ana-Belén Blázquez, Francisco Sobrino, Belén Borrego, Margarita Sáiz, Juan-Carlos Saiz
Published 2012-01-01

Silver Nanoparticles as Nanoantibiotics: A Comparative Analysis of their Toxicity on Biological Systems of Different Complexity

by Roberto Vázquez-Muñoz, Belén Borrego-Rivero, Karla Oyuky Juárez-Moreno, Maritza Roxana García-García, Josué David Mota-Morales, Nina Bogdanchikova, Alejandro Huerta-Saquero
Published 2018-09-01

Safety and Efficacy upon Infection in Sheep with Rift Valley Fever Virus ZH548-rA2, a Triple Mutant Rescued Virus

by Sandra Moreno, Gema Lorenzo, Álvaro López-Valiñas, Nuria de la Losa, Celia Alonso, Elena Charro, José I. Núñez, Pedro J. Sánchez-Cordón, Belén Borrego, Alejandro Brun
Published 2024-01-01

Evaluation of silver nanoparticles for the prevention of SARS-CoV-2 infection in health workers: In vitro and in vivo.

by Horacio Almanza-Reyes, Sandra Moreno, Ismael Plascencia-López, Martha Alvarado-Vera, Leslie Patrón-Romero, Belén Borrego, Alberto Reyes-Escamilla, Daniel Valencia-Manzo, Alejandro Brun, Alexey Pestryakov, Nina Bogdanchikova
Published 2021-01-01