Cell-based small-molecule compound screen identifies fenretinide as potential therapeutic for translocation-positive rhabdomyosarcoma.

by David Herrero Martín, Aleksandar Boro, Beat W Schäfer
Published 2013-01-01

Fenretinide Acts as Potent Radiosensitizer for Treatment of Rhabdomyosarcoma Cells

by Eva Brack, Eva Brack, Eva Brack, Sabine Bender, Marco Wachtel, Marco Wachtel, Martin Pruschy, Beat W. Schäfer, Beat W. Schäfer
Published 2021-06-01

Functional Classification of Fusion Proteins in Sarcoma

by Marco Wachtel, Didier Surdez, Thomas G. P. Grünewald, Beat W. Schäfer
Published 2024-03-01

ESF-EMBO Symposium Molecular Biology and Innovative Therapies in Sarcomas of Childhood and AdolescenceSept 29 – Oct 4, Polonia Castle Pultusk, Poland

by Beat W Schäfer, Ewa eKoscielniak, Heinrich eKovar, Simone eFulda
Published 2013-06-01

Furin targeted drug delivery for treatment of rhabdomyosarcoma in a mouse model.

by Katarina Hajdin, Valentina D'Alessandro, Felix K Niggli, Beat W Schäfer, Michele Bernasconi
Published 2010-01-01

A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/MCL-1 balance as target for re-sensitization to first-line therapy in recurre...

by Gabriele Manzella, Devmini C. Moonamale, Michaela Römmele, Peter Bode, Marco Wachtel, Beat W. Schäfer
Published 2021-09-01

High Frequency of Tumor Propagating Cells in Fusion-Positive Rhabdomyosarcoma

by Melanie Generali, Sampoorna Satheesha, Peter K. Bode, Debora Wanner, Beat W. Schäfer, Elisa A. Casanova
Published 2021-08-01

The Proprotein Convertase Furin Contributes to Rhabdomyosarcoma Malignancy by Promoting Vascularization, Migration and Invasion.

by Patricia Jaaks, Valentina D'Alessandro, Nicole Grob, Sina Büel, Katarina Hajdin, Beat W Schäfer, Michele Bernasconi
Published 2016-01-01

Author Correction: CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma

by Vadim Saratov, Quy A. Ngo, Gloria Pedot, Semjon Sidorov, Marco Wachtel, Felix K. Niggli, Beat W. Schäfer
Published 2022-08-01

CRISPR activation screen identifies TGFβ-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma

by Vadim Saratov, Quy A. Ngo, Gloria Pedot, Semjon Sidorov, Marco Wachtel, Felix K. Niggli, Beat W. Schäfer
Published 2022-06-01

USP19 deubiquitinates EWS-FLI1 to regulate Ewing sarcoma growth

by Maria E. Gierisch, Gloria Pedot, Franziska Walser, Laura A. Lopez-Garcia, Patricia Jaaks, Felix K. Niggli, Beat W. Schäfer
Published 2019-01-01

Corrigendum to “Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization” [Neoplasia volume 27 (2022) pp. 100784/Number C]

by Gloria Pedot, Joana Graça Marques, Philip P. Ambühl, Marco Wachtel, Stephanie Kasper, Quy A. Ngo, Felix K. Niggli, Beat W. Schäfer
Published 2022-09-01

Anemia and survival in childhood acute lymphoblastic leukemia

by Oliver Teuffel, Martin Stanulla, Gunnar Cario, Wolf D. Ludwig, Silja Rottgers, Beat W. Schafer, Martin Zimmermann, Martin Schrappe, Felix K. Niggli
Published 2008-11-01

Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization

by Gloria Pedot, Joana Graça Marques, Philip P. Ambühl, Marco Wachtel, Stephanie Kasper, Quy A. Ngo, Felix K. Niggli, Beat W. Schäfer
Published 2022-05-01

Genomic and Epigenetic Changes Drive Aberrant Skeletal Muscle Differentiation in Rhabdomyosarcoma

by Silvia Pomella, Sara G. Danielli, Rita Alaggio, Willemijn B. Breunis, Ebrahem Hamed, Joanna Selfe, Marco Wachtel, Zoe S. Walters, Beat W. Schäfer, Rossella Rota, Janet M. Shipley, Simone Hettmer
Published 2023-05-01

A Perspective on Polo-Like Kinase-1 Inhibition for the Treatment of Rhabdomyosarcomas

by Susanne A. Gatz, Susanne A. Gatz, Ewa Aladowicz, Michela Casanova, Julia C. Chisholm, Julia C. Chisholm, Pamela R. Kearns, Simone Fulda, Birgit Geoerger, Beat W. Schäfer, Janet M. Shipley
Published 2019-11-01

Novel FGFR4-Targeting Single-Domain Antibodies for Multiple Targeted Therapies against Rhabdomyosarcoma

by Nagjie Alijaj, Sandrine Moutel, Zelia L. Gouveia, Maxim Gray, Maurizio Roveri, Dzhangar Dzhumashev, Florian Weber, Gianmarco Meier, Paola Luciani, Jochen K. Rössler, Beat W. Schäfer, Franck Perez, Michele Bernasconi
Published 2020-11-01

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency

by Joana G Marques, Berkley E Gryder, Blaz Pavlovic, Yeonjoo Chung, Quy A Ngo, Fabian Frommelt, Matthias Gstaiger, Young Song, Katharina Benischke, Dominik Laubscher, Marco Wachtel, Javed Khan, Beat W Schäfer
Published 2020-08-01

Combined Inhibition of Epigenetic Readers and Transcription Initiation Targets the EWS-ETS Transcriptional Program in Ewing Sarcoma

by Günther H.S. Richter, Tim Hensel, Oxana Schmidt, Vadim Saratov, Kristina von Heyking, Fiona Becker-Dettling, Carolin Prexler, Hsi-Yu Yen, Katja Steiger, Simone Fulda, Uta Dirksen, Wilko Weichert, Shudong Wang, Stefan Burdach, Beat W. Schäfer
Published 2020-01-01

CD133 positive embryonal rhabdomyosarcoma stem-like cell population is enriched in rhabdospheres.

by Dagmar Walter, Sampoorna Satheesha, Patrick Albrecht, Beat C Bornhauser, Valentina D'Alessandro, Susanne M Oesch, Hubert Rehrauer, Ivo Leuschner, Ewa Koscielniak, Carole Gengler, Holger Moch, Michele Bernasconi, Felix K Niggli, Beat W Schäfer, CWS Study Group
Published 2011-01-01