Crystal Packing Differences as a Key Factor for Stabilization of the N-Terminal Fragment of the Human HINT1 Protein

by Rafał Dolot, Aleksandra Mikołajczyk, Barbara Nawrot
Published 2023-08-01

First High-Resolution Crystal Structures of DNA:2′-<i>O</i>-Methyl-RNA Heteroduplexes

by Rafał Dolot, Anna Maciaszek, Barbara Mikołajczyk, Barbara Nawrot
Published 2022-05-01

DNA Modified with Boron–Metal Cluster Complexes [M(C₂B₉H₁₁)₂]—Synthesis, Properties, and Applications

by Agnieszka B. Olejniczak, Barbara Nawrot, Zbigniew J. Leśnikowski
Published 2018-11-01

Boron Clusters as Enhancers of RNase H Activity in the Smart Strategy of Gene Silencing by Antisense Oligonucleotides

by Damian Kaniowski, Katarzyna Kulik, Justyna Suwara, Katarzyna Ebenryter-Olbińska, Barbara Nawrot
Published 2022-10-01

Synthesis of New Derivatives of Benzofuran as Potential Anticancer Agents

by Mariola Napiórkowska, Marcin Cieślak, Julia Kaźmierczak-Barańska, Karolina Królewska-Golińska, Barbara Nawrot
Published 2019-04-01

Sgt1 Regulates α-Synuclein Subcellular Localization and Expression of Parkinson’s Disease Related Genes, <i>PINK1</i> and <i>PARK9</i>

by Anastasiia Bohush, Agnieszka Góral, Małgorzata Sierant, Barbara Nawrot, Wiesława Leśniak, Anna Filipek
Published 2021-11-01

EGFR-Targeted Cellular Delivery of Therapeutic Nucleic Acids Mediated by Boron Clusters

by Damian Kaniowski, Justyna Suwara, Katarzyna Ebenryter-Olbińska, Agata Jakóbik-Kolon, Barbara Nawrot
Published 2022-11-01

Formation of an RNA Quadruplex-Duplex Hybrid in Living Cells between mRNA of the Epidermal Growth Factor Receptor (EGFR) and a G-Rich Antisense Oligoribonucleotide

by Dorota Gudanis, Damian Kaniowski, Katarzyna Kulik, Daniel Baranowski, Zofia Gdaniec, Barbara Nawrot
Published 2020-10-01

Evaluation of BACE1 Silencing in Cellular Models

by Malgorzata Sierant, Katarzyna Kubiak, Julia Kazmierczak-Baranska, Masaki Warashina, Tomoko Kuwabara, Barbara Nawrot
Published 2009-01-01

2-Selenouridine, a Modified Nucleoside of Bacterial tRNAs, Its Reactivity in the Presence of Oxidizing and Reducing Reagents

by Katarzyna Kulik, Klaudia Sadowska, Ewelina Wielgus, Barbara Pacholczyk-Sienicka, Elzbieta Sochacka, Barbara Nawrot
Published 2022-07-01

Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase

by Damian Kaniowski, Katarzyna Kulik, Katarzyna Ebenryter-Olbińska, Ewelina Wielgus, Zbigniew Lesnikowski, Barbara Nawrot
Published 2020-05-01

Different Oxidation Pathways of 2-Selenouracil and 2-Thiouracil, Natural Components of Transfer RNA

by Katarzyna Kulik, Klaudia Sadowska, Ewelina Wielgus, Barbara Pacholczyk-Sienicka, Elzbieta Sochacka, Barbara Nawrot
Published 2020-08-01

DNA oligonucleotides with stereodefined phenylphosphonate and phosphonothioate internucleotide bonds: synthesis and physico-chemical properties

by Milena Sobczak, Tommy Johansson, Marek Bulkowski, Marek Sochacki, Gaston Lavén, Barbara Mikolaczyk, Jacek Stawinski, Barbara Nawrot
Published 2011-12-01

High Boron-loaded DNA-Oligomers as Potential Boron Neutron Capture Therapy and Antisense Oligonucleotide Dual-Action Anticancer Agents

by Damian Kaniowski, Katarzyna Ebenryter-Olbińska, Milena Sobczak, Błażej Wojtczak, Sławomir Janczak, Zbigniew J. Leśnikowski, Barbara Nawrot
Published 2017-08-01

New Thalidomide-Resembling Dicarboximides Target ABC50 Protein and Show Antileukemic and Immunomodulatory Activities

by Marcin Cieślak, Julia Kaźmierczak-Barańska, Karolina Królewska-Golińska, Mariola Napiórkowska, Iga Stukan, Urszula Wojda, Barbara Nawrot
Published 2019-09-01

New Succinimides with Potent Anticancer Activity: Synthesis, Activation of Stress Signaling Pathways and Characterization of Apoptosis in Leukemia and Cervical Cancer Cells

by Marcin Cieślak, Mariola Napiórkowska, Julia Kaźmierczak-Barańska, Karolina Królewska-Golińska, Anna Hawrył, Iwona Wybrańska, Barbara Nawrot
Published 2021-04-01

Novel nucleic acid analogs with a chimeric phosphinate/phosphate backbone; synthesis and biophysical properties

by Barbara Nawrot, Olga Michalak, Magdalena Janicka, Maria Maszewska, Marzena Wojcik, Genowefa Nowak, Barbara Mikolajczyk, Wojciech J. Stec
Published 2004-02-01

Specific Silencing of L392V PSEN1 Mutant Allele by RNA Interference

by Malgorzata Sierant, Alina Paduszynska, Julia Kazmierczak-Baranska, Benedetta Nacmias, Sandro Sorbi, Silvia Bagnoli, Elzbieta Sochacka, Barbara Nawrot
Published 2011-01-01

Composites of Nucleic Acids and Boron Clusters (C₂B₁₀H₁₂) as Functional Nanoparticles for Downregulation of EGFR Oncogene in Cancer Cells

by Damian Kaniowski, Katarzyna Ebenryter-Olbińska, Katarzyna Kulik, Justyna Suwara, Wojciech Cypryk, Agata Jakóbik-Kolon, Zbigniew Leśnikowski, Barbara Nawrot
Published 2021-05-01

<i>Escherichia coli</i> tRNA 2-Selenouridine Synthase (SelU): Elucidation of Substrate Specificity to Understand the Role of <i>S</i>-Geranyl-tRNA in the Conversion of 2-Thio- into...

by Patrycja Szczupak, Malgorzata Sierant, Ewelina Wielgus, Ewa Radzikowska-Cieciura, Katarzyna Kulik, Agnieszka Krakowiak, Paulina Kuwerska, Grazyna Leszczynska, Barbara Nawrot
Published 2022-05-01