Monitoring NLRP3 Inflammasome Activation and Exhaustion in Clinical Samples: A Refined Flow Cytometry Protocol for ASC Speck Formation Measurement Directly in Whole Blood after Ex...

by Rémy Coudereau, Morgane Gossez, Bénédicte F Py, Thomas Henry, Anne-Claire Lukaszewicz, Guillaume Monneret, Fabienne Venet
Published 2022-10-01

Altered Ex Vivo NLRP3 Inflammasome Activation Is Associated with 28-Day Mortality in Septic Patients

by Rémy Coudereau, Guillaume Monneret, Anne-Claire Lukaszewicz, Bénédicte F. Py, Laurent Argaud, Martin Cour, Frank Bidar, Morgane Gossez, Fabienne Venet
Published 2023-12-01

Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11

by Brice Lagrange, Sacha Benaoudia, Pierre Wallet, Flora Magnotti, Angelina Provost, Fanny Michal, Amandine Martin, Flaviana Di Lorenzo, Bénédicte F. Py, Antonio Molinaro, Thomas Henry
Published 2018-01-01

Caspase-11 Controls Interleukin-1β Release through Degradation of TRPC1

by Bénédicte F. Py, Mingzhi Jin, Bimal N. Desai, Anirudh Penumaka, Hong Zhu, Maike Kober, Alexander Dietrich, Marta M. Lipinski, Thomas Henry, David E. Clapham, Junying Yuan
Published 2014-03-01

Caspase-1 activity affects AIM2 speck formation/ stability through a negative feedback loop.

by Carole eJuruj, Virginie eLelogeais, Roberto ePierini, Magali ePerret, Bénédicte F Py, Yvan eJamilloux, Petr eBroz, Florence eAder, Mathias eFaure, Thomas eHenry
Published 2013-04-01

IFN-γ extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection.

by Pierre Wallet, Sacha Benaoudia, Amandine Mosnier, Brice Lagrange, Amandine Martin, Helena Lindgren, Igor Golovliov, Fanny Michal, Pauline Basso, Sophia Djebali, Angelina Provost, Omran Allatif, Etienne Meunier, Petr Broz, Masahiro Yamamoto, Bénédicte F Py, Eric Faudry, Anders Sjöstedt, Thomas Henry
Published 2017-10-01

NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly

by Tingting Niu, Charlotte De Rosny, Séverine Chautard, Amaury Rey, Danish Patoli, Marine Groslambert, Camille Cosson, Brice Lagrange, Zhirong Zhang, Orane Visvikis, Sabine Hacot, Maggy Hologne, Olivier Walker, Jeimin Wong, Ping Wang, Roméo Ricci, Thomas Henry, Laurent Boyer, Virginie Petrilli, Bénédicte F. Py
Published 2021-10-01

Role of Protein Misfolding in DFNA9 Hearing Loss

by Yao, Jianhua, Py, Bénédicte F., Zhu, Hong, Bao, Jianxin, Yuan, Junying
Published 2019