Reproducible generation of human midbrain organoids for in vitro modeling of Parkinson’s disease

by Sarah Louise Nickels, Jennifer Modamio, Bárbara Mendes-Pinheiro, Anna Sophia Monzel, Fay Betsou, Jens Christian Schwamborn
Published 2020-07-01

Bone Marrow Mesenchymal Stem Cells' Secretome Exerts Neuroprotective Effects in a Parkinson's Disease Rat Model

by Bárbara Mendes-Pinheiro, Bárbara Mendes-Pinheiro, Sandra I. Anjo, Bruno Manadas, Jorge D. Da Silva, Jorge D. Da Silva, Ana Marote, Ana Marote, Leo A. Behie, Fábio G. Teixeira, Fábio G. Teixeira, António J. Salgado, António J. Salgado
Published 2019-11-01

Impact of Aging on the 6-OHDA-Induced Rat Model of Parkinson’s Disease

by Sandra Barata-Antunes, Fábio G. Teixeira, Bárbara Mendes-Pinheiro, Ana V. Domingues, Helena Vilaça-Faria, Ana Marote, Deolinda Silva, Rui A. Sousa, António J. Salgado
Published 2020-05-01

Unilateral Intrastriatal 6-Hydroxydopamine Lesion in Mice: A Closer Look into Non-Motor Phenotype and Glial Response

by Bárbara Mendes-Pinheiro, Carina Soares-Cunha, Ana Marote, Eduardo Loureiro-Campos, Jonas Campos, Sandra Barata-Antunes, Daniela Monteiro-Fernandes, Diogo Santos, Sara Duarte-Silva, Luísa Pinto, António José Salgado
Published 2021-10-01

MODULATION OF BRAIN CONNECTIVITY, STRUCTURE, NEURON AND GLIA, AND MOTOR FUNCTION BY SAFINAMIDE MULTIMODAL ACTIONS IN A PRE-CLINICAL MODEL OF PARKINSON’S DISEASE

by Bruna Araújo, Jonas Campos, Rita Caridade-Silva, Bárbara Mendes-Pinheiro, Raquel Marques, Sandra Barata, Rui Lima, Joana Martins-Macedo, Eduardo Gomes, Benoit Larrat, António Salgado, Sébastien Mériaux, Sofia Domingues, Fábio Teixeira
Published 2023-10-01

Constitutive deficiency of the neurogenic hippocampal modulator AP2γ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods

by Eduardo Loureiro-Campos, António Mateus-Pinheiro, Patrícia Patrício, Carina Soares-Cunha, Joana Silva, Vanessa Morais Sardinha, Bárbara Mendes-Pinheiro, Tiago Silveira-Rosa, Ana Verónica Domingues, Ana João Rodrigues, João Oliveira, Nuno Sousa, Nuno Dinis Alves, Luísa Pinto
Published 2021-12-01

Preclinical Assessment of Mesenchymal-Stem-Cell-Based Therapies in Spinocerebellar Ataxia Type 3

by Joana Sofia Correia, Andreia Neves-Carvalho, Bárbara Mendes-Pinheiro, Joel Pires, Fábio Gabriel Teixeira, Rui Lima, Susana Monteiro, Nuno André Silva, Carina Soares-Cunha, Sofia Cravino Serra, Sara Duarte-Silva, Andreia Teixeira-Castro, António José Salgado, Patrícia Maciel
Published 2021-11-01

Treating Parkinson’s Disease with Human Bone Marrow Mesenchymal Stem Cell Secretome: A Translational Investigation Using Human Brain Organoids and Different Routes of In Vivo Admin...

by Bárbara Mendes-Pinheiro, Jonas Campos, Ana Marote, Carina Soares-Cunha, Sarah L. Nickels, Anna S. Monzel, Jorge R. Cibrão, Eduardo Loureiro-Campos, Sofia C. Serra, Sandra Barata-Antunes, Sara Duarte-Silva, Luísa Pinto, Jens C. Schwamborn, António J. Salgado
Published 2023-11-01