Synthetic Biology of Fungal Natural Products

by Derek J. Mattern, Derek J. Mattern, Vito eValiante, Shiela E. Unkles, Axel A Brakhage, Axel A Brakhage
Published 2015-07-01

Conidial surface proteins at the interface of fungal infections.

by Matthew G Blango, Olaf Kniemeyer, Axel A Brakhage
Published 2019-09-01

Human and plant fungal pathogens: the role of secondary metabolites.

by Daniel H Scharf, Thorsten Heinekamp, Axel A Brakhage
Published 2014-01-01

Aspergillus fumigatus melanins: Interference with the host endocytosis pathway and impact on virulence

by Thorsten eHeinekamp, Andreas eThywissen, Juliane eMacheleidt, Sophia eKeller, Vito eValiante, Axel A Brakhage, Axel A Brakhage
Published 2013-01-01

Systems biology of fungal infection

by Fabian eHorn, Thorsten eHeinekamp, Olaf eKniemeyer, Johannes ePollmächer, Vito eValiante, Axel A Brakhage, Axel A Brakhage
Published 2012-04-01

The Pheromone Module SteC-MkkB-MpkB-SteD-HamE Regulates Development, Stress Responses and Secondary Metabolism in Aspergillus fumigatus

by Dean Frawley, Maria C. Stroe, Berl R. Oakley, Thorsten Heinekamp, Maria Straßburger, Alastair B. Fleming, Axel A. Brakhage, Axel A. Brakhage, Özgür Bayram
Published 2020-05-01

Isolation and immunofluorescence staining of Aspergillus fumigatus conidia-containing phagolysosomes

by Marie Goldmann, Franziska Schmidt, Irene Kyrmizi, Georgios Chamilos, Axel A. Brakhage
Published 2021-03-01

Automated image analysis of the host-pathogen interaction between phagocytes and Aspergillus fumigatus.

by Franziska Mech, Andreas Thywissen, Reinhard Guthke, Axel A Brakhage, Marc Thilo Figge
Published 2011-01-01

Hyperspectral Imaging Using Intracellular Spies: Quantitative Real-Time Measurement of Intracellular Parameters In Vivo during Interaction of the Pathogenic Fungus Aspergillus fumi...

by Sara Mohebbi, Florian Erfurth, Philipp Hennersdorf, Axel A Brakhage, Hans Peter Saluz
Published 2016-01-01

The Aspergillus fumigatus cell wall integrity signalling pathway: drug target, compensatory pathways and virulence

by Vito eValiante, Juliane eMacheleidt, Martin eFöge, Axel A Brakhage
Published 2015-04-01

CRISPR-Cas9-Based Discovery of the Verrucosidin Biosynthesis Gene Cluster in Penicillium polonicum

by Silvia Valente, Silvia Valente, Edoardo Piombo, Edoardo Piombo, Volker Schroeckh, Giovanna Roberta Meloni, Giovanna Roberta Meloni, Thorsten Heinekamp, Axel A. Brakhage, Axel A. Brakhage, Davide Spadaro, Davide Spadaro
Published 2021-05-01

Dynamic optimization reveals alveolar epithelial cells as key mediators of host defense in invasive aspergillosis.

by Jan Ewald, Flora Rivieccio, Lukáš Radosa, Stefan Schuster, Axel A Brakhage, Christoph Kaleta
Published 2021-12-01

Mutations in EEA1 are associated with allergic bronchopulmonary aspergillosis and affect phagocytosis of Aspergillus fumigatus by human macrophages.

by Nicola L D Overton, Axel A Brakhage, Andreas Thywißen, David W Denning, Paul Bowyer
Published 2018-01-01

<i>Aspergillus fumigatus</i> versus Genus <i>Aspergillus</i>: Conservation, Adaptive Evolution and Specific Virulence Genes

by Shishir K. Gupta, Mugdha Srivastava, Özge Osmanoglu, Zhuofei Xu, Axel A. Brakhage, Thomas Dandekar
Published 2021-09-01

Phenotypic and Proteomic Analysis of the Aspergillus fumigatus ΔPrtT, ΔXprG and ΔXprG/ΔPrtT Protease-Deficient Mutants

by Einav Shemesh, Benjamin Hanf, Benjamin Hanf, Shelly Hagag, Shani Attias, Yana Shadkchan, Boris Fichtman, Amnon Harel, Thomas Krüger, Thomas Krüger, Axel A. Brakhage, Axel A. Brakhage, Olaf Kniemeyer, Olaf Kniemeyer, Nir Osherov
Published 2017-12-01

Conidial dihydroxynaphthalene melanin of the human pathogenic fungus Aspergillus fumigatus interferes with the host endocytosis pathway

by Andreas eThywißen, Andreas eThywißen, Thorsten eHeinekamp, Thorsten eHeinekamp, Hans-Martin eDahse, Jeannette eSchmaler-Ripcke, Sandor eNietsche, Peter F. Zipfel, Axel A Brakhage, Axel A Brakhage
Published 2011-05-01

Characterization of the Aspergillus fumigatus detoxification systems for reactive nitrogen intermediates and their impact on virulence

by Katrin eLapp, Martin eVödisch, Kristin eKroll, Maria eStrassburger, Olaf eKniemeyer, Olaf eKniemeyer, Olaf eKniemeyer, Thorsten eHeinekamp, Thorsten eHeinekamp, Axel A Brakhage, Axel A Brakhage
Published 2014-09-01

HapX Mediates Iron Homeostasis in the Pathogenic Dermatophyte Arthroderma benhamiae but Is Dispensable for Virulence.

by Antje Kröber, Kirstin Scherlach, Peter Hortschansky, Ekaterina Shelest, Peter Staib, Olaf Kniemeyer, Axel A Brakhage
Published 2016-01-01

Direct Binding of the pH-Regulated Protein 1 (Pra1) from Candida albicans Inhibits Cytokine Secretion by Mouse CD4+ T Cells

by Arne Bergfeld, Prasad Dasari, Prasad Dasari, Sandra Werner, Timothy R. Hughes, Wen-Chao Song, Peter Hortschansky, Peter Hortschansky, Axel A. Brakhage, Axel A. Brakhage, Thomas Hünig, Peter F. Zipfel, Peter F. Zipfel, Niklas Beyersdorf
Published 2017-05-01

Targeted induction of a silent fungal gene cluster encoding the bacteria-specific germination inhibitor fumigermin

by Maria Cristina Stroe, Tina Netzker, Kirstin Scherlach, Thomas Krüger, Christian Hertweck, Vito Valiante, Axel A Brakhage
Published 2020-02-01