Novel thiazolidinone-containing compounds, without the well-known sulphonamide zinc-binding group acting as human carbonic anhydrase IX inhibitors

by Özlen Güzel-Akdemir, Andrea Angeli, Kübra Demir, Claudiu T. Supuran, Atilla Akdemir
Published 2018-01-01

Novel Indole-Based Hydrazones as Potent Inhibitors of the α-class Carbonic Anhydrase from Pathogenic Bacterium <i>Vibrio cholerae</i>

by Kübra Demir-Yazıcı, Özlen Güzel-Akdemir, Andrea Angeli, Claudiu T. Supuran, Atilla Akdemir
Published 2020-04-01

Novel 2-indolinones containing a sulfonamide moiety as selective inhibitors of candida β-carbonic anhydrase enzyme

by Atilla Akdemir, Andrea Angeli, Füsun Göktaş, Pınar Eraslan Elma, Nilgün Karalı, Claudiu T. Supuran
Published 2019-01-01

Thiosemicarbazide-Substituted Coumarins as Selective Inhibitors of the Tumor Associated Human Carbonic Anhydrases IX and XII

by Arzu Gumus, Murat Bozdag, Atilla Akdemir, Andrea Angeli, Silvia Selleri, Fabrizio Carta, Claudiu T. Supuran
Published 2022-07-01

Five- and Six-Membered Nitrogen-Containing Compounds as Selective Carbonic Anhydrase Activators

by Adriano Mollica, Giorgia Macedonio, Azzurra Stefanucci, Simone Carradori, Atilla Akdemir, Andrea Angeli, Claudiu T. Supuran
Published 2017-12-01

Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII

by Kübra Demir-Yazıcı, Silvia Bua, Nurgül Mutlu Akgüneş, Atilla Akdemir, Claudiu T. Supuran, Özlen Güzel-Akdemir
Published 2019-05-01

Development of Thiazolidinones as Fungal Carbonic Anhydrase Inhibitors

by Özlen Güzel-Akdemir, Simone Carradori, Rossella Grande, Kübra Demir-Yazıcı, Andrea Angeli, Claudiu T. Supuran, Atilla Akdemir
Published 2020-04-01

Azole-Based Compounds That Are Active against <i>Candida</i> Biofilm: In Vitro<i>,</i> In Vivo and In Silico Studies

by Simone Carradori, Alessandra Ammazzalorso, Barbara De Filippis, Ahmet Fatih Şahin, Atilla Akdemir, Anastasia Orekhova, Graziana Bonincontro, Giovanna Simonetti
Published 2022-10-01

Fibrate-based N-acylsulphonamides targeting carbonic anhydrases: synthesis, biochemical evaluation, and docking studies

by Alessandra Ammazzalorso, Simone Carradori, Andrea Angeli, Atilla Akdemir, Barbara De Filippis, Marialuigia Fantacuzzi, Letizia Giampietro, Cristina Maccallini, Rosa Amoroso, Claudiu T. Supuran
Published 2019-01-01

Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms

by Melissa D’Ascenzio, Paolo Guglielmi, Simone Carradori, Daniela Secci, Rosalba Florio, Adriano Mollica, Mariangela Ceruso, Atilla Akdemir, Anatoly P. Sobolev, Claudiu T. Supuran
Published 2017-01-01

New azolyl-derivatives as multitargeting agents against breast cancer and fungal infections: synthesis, biological evaluation and docking study

by Cristina Maccallini, Marialucia Gallorini, Francesca Sisto, Atilla Akdemir, Alessandra Ammazzalorso, Barbara De Filippis, Marialuigia Fantacuzzi, Letizia Giampietro, Simone Carradori, Amelia Cataldi, Rosa Amoroso
Published 2021-01-01

Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold

by Giulia Rotondi, Paolo Guglielmi, Simone Carradori, Daniela Secci, Celeste De Monte, Barbara De Filippis, Cristina Maccallini, Rosa Amoroso, Roberto Cirilli, Atilla Akdemir, Andrea Angeli, Claudiu T. Supuran
Published 2019-01-01

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment

by Andrea Angeli, Fabrizio Carta, Alessio Nocentini, Jean-Yves Winum, Raivis Zalubovskis, Atilla Akdemir, Valentina Onnis, Wagdy M. Eldehna, Clemente Capasso, Giuseppina De Simone, Simona Maria Monti, Simone Carradori, William A. Donald, Shoukat Dedhar, Claudiu T. Supuran
Published 2020-10-01