Determinants of outcome following PSMA-based radioligand therapy and mechanisms of resistance in patients with metastatic castration-resistant prostate cancer

by Louise Kostos, James P. Buteau, Michael S. Hofman, Arun A. Azad
Published 2023-06-01

Utility and Clinical Application of Circulating Tumor DNA (ctDNA) in Advanced Prostate Cancer

by Louise Kostos, Heidi Fettke, Edmond M. Kwan, Arun A. Azad
Published 2023-07-01

Safety of Lutetium-177 prostate-specific membrane antigen-617 (PSMA-617) radioligand therapy in the setting of severe renal impairment: a case report and literature review

by Duncan E. K. Sutherland, Raghava Kashyap, Price Jackson, James P. Buteau, Declan G. Murphy, Brian Kelly, Lavinia Spain, Shahneen Sandhu, Arun A. Azad, Elizabeth Medhurst, Grace Kong, Michael S. Hofman
Published 2023-06-01

AlphaBet: Combination of Radium-223 and [177Lu]Lu-PSMA-I&T in men with metastatic castration-resistant prostate cancer (clinical trial protocol)

by Louise Kostos, Louise Kostos, James P. Buteau, James P. Buteau, James P. Buteau, Theresa Yeung, Juliana Di Iulio, Jing Xie, Anthony Cardin, Anthony Cardin, Anthony Cardin, Kwang Y. Chin, Kwang Y. Chin, Brittany Emmerson, Brittany Emmerson, Katie L. Owen, Katie L. Owen, Belinda S. Parker, Belinda S. Parker, Heidi Fettke, Heidi Fettke, Luc Furic, Luc Furic, Arun A. Azad, Arun A. Azad, Michael S. Hofman, Michael S. Hofman, Michael S. Hofman
Published 2022-11-01

Analytical validation of an error-corrected ultra-sensitive ctDNA next-generation sequencing assay

by Heidi Fettke, Jason A Steen, Edmond M Kwan, Patricia Bukczynska, Shivakumar Keerthikumar, David Goode, Maria Docanto, Nicole Ng, Luciano Martelotto, Christine Hauser, Melissa C Southey, Arun A Azad, Tu Nguyen-Dumont
Published 2020-08-01

Low rate of severe-end-stage kidney disease after SABR for localised primary kidney cancer

by Muhammad Ali, Kendrick Koo, David Chang, Phil Chan, Sheng F. Oon, Daniel Moon, Declan G. Murphy, Renu Eapen, Jeremy Goad, Nathan Lawrentschuk, Arun A. Azad, Sarat Chander, Mark Shaw, Nicholas Hardcastle, Shankar Siva
Published 2024-02-01

Clinical and genomic insights into circulating tumor DNA-based alterations across the spectrum of metastatic hormone-sensitive and castrate-resistant prostate cancer

by Manish Kohli, Winston Tan, Tiantian Zheng, Amy Wang, Carlos Montesinos, Calven Wong, Pan Du, Shidong Jia, Siddhartha Yadav, Lisa G. Horvath, Kate L. Mahon, Edmond M. Kwan, Heidi Fettke, Jianjun Yu, Arun A. Azad
Published 2020-04-01

NeoAdjuvant pembrolizumab and STEreotactic radiotherapy prior to nephrectomy for renal cell carcinoma (NAPSTER): A phase II randomised clinical trial

by Muhammad Ali, Simon Wood, David Pryor, Daniel Moon, Mathias Bressel, Arun A. Azad, Catherine Mitchell, Declan Murphy, Homi Zargar, Nick Hardcastle, Jamie Kearsley, Renu Eapen, Lih Ming Wong, Katharine Cuff, Nathan Lawrentschuk, Paul J. Neeson, Shankar Siva
Published 2023-06-01

BRCA-deficient metastatic prostate cancer has an adverse prognosis and distinct genomic phenotypeResearch in context

by Heidi Fettke, Chao Dai, Edmond M. Kwan, Tiantian Zheng, Pan Du, Nicole Ng, Patricia Bukczynska, Maria Docanto, Louise Kostos, Siavash Foroughi, Stephen Brown, Lisa-Jane K. Graham, Kate Mahon, Lisa G. Horvath, Shidong Jia, Manish Kohli, Arun A. Azad
Published 2023-09-01

Relationship between Circulating Lipids and Cytokines in Metastatic Castration-Resistant Prostate Cancer

by Hui-Ming Lin, Nicole Yeung, Jordan F. Hastings, David R. Croucher, Kevin Huynh, Thomas G. Meikle, Natalie A. Mellett, Edmond M. Kwan, Ian D. Davis, Ben Tran, Kate L. Mahon, Alison Zhang, Martin R. Stockler, Karen Briscoe, Gavin Marx, Patricia Bastick, Megan L. Crumbaker, Anthony M. Joshua, Arun A. Azad, Peter J. Meikle, Lisa G. Horvath
Published 2021-10-01

Combined impact of lipidomic and genetic aberrations on clinical outcomes in metastatic castration-resistant prostate cancer

by Blossom Mak, Hui-Ming Lin, Edmond M. Kwan, Heidi Fettke, Ben Tran, Ian D. Davis, Kate Mahon, Martin R. Stockler, Karen Briscoe, Gavin Marx, Alison Zhang, Megan Crumbaker, Winston Tan, Kevin Huynh, Thomas G. Meikle, Natalie A. Mellett, Andrew J. Hoy, Pan Du, Jianjun Yu, Shidong Jia, Anthony M. Joshua, David J. Waugh, Lisa M. Butler, Manish Kohli, Peter J. Meikle, Arun A. Azad, Lisa G. Horvath
Published 2022-03-01

Overcoming enzalutamide resistance in metastatic prostate cancer by targeting sphingosine kinase

by Hui-Ming Lin, Blossom Mak, Nicole Yeung, Kevin Huynh, Thomas G. Meikle, Natalie A. Mellett, Edmond M. Kwan, Heidi Fettke, Ben Tran, Ian D. Davis, Kate L. Mahon, Alison Zhang, Martin R. Stockler, Karen Briscoe, Gavin Marx, Megan Crumbaker, Phillip D. Stricker, Pan Du, Jianjun Yu, Shidong Jia, Tahlia Scheinberg, Michael Fitzpatrick, Paul Bonnitcha, David R. Sullivan, Anthony M. Joshua, Arun A. Azad, Lisa M. Butler, Peter J. Meikle, Lisa G. Horvath
Published 2021-10-01

The MURAL collection of prostate cancer patient-derived xenografts enables discovery through preclinical models of uro-oncology

by Gail P. Risbridger, Ashlee K. Clark, Laura H. Porter, Roxanne Toivanen, Andrew Bakshi, Natalie L. Lister, David Pook, Carmel J. Pezaro, Shahneen Sandhu, Shivakumar Keerthikumar, Rosalia Quezada Urban, Melissa Papargiris, Jenna Kraska, Heather B. Madsen, Hong Wang, Michelle G. Richards, Birunthi Niranjan, Samantha O’Dea, Linda Teng, William Wheelahan, Zhuoer Li, Nicholas Choo, John F. Ouyang, Heather Thorne, Lisa Devereux, Rodney J. Hicks, Shomik Sengupta, Laurence Harewood, Mahesh Iddawala, Arun A. Azad, Jeremy Goad, Jeremy Grummet, John Kourambas, Edmond M. Kwan, Daniel Moon, Declan G. Murphy, John Pedersen, David Clouston, Sam Norden, Andrew Ryan, Luc Furic, David L. Goode, Mark Frydenberg, Mitchell G. Lawrence, Renea A. Taylor
Published 2021-08-01