Itaconate modulates tricarboxylic acid and redox metabolism to mitigate reperfusion injury

by Thekla Cordes, Alfredo Lucas, Ajit S. Divakaruni, Anne N. Murphy, Pedro Cabrales, Christian M. Metallo
Published 2020-02-01

NaCT/SLC13A5 facilitates citrate import and metabolism under nutrient-limited conditions

by Avi Kumar, Thekla Cordes, Anna E. Thalacker-Mercer, Ana M. Pajor, Anne N. Murphy, Christian M. Metallo
Published 2021-09-01

Sub-nanowatt microfluidic single-cell calorimetry

by Sahngki Hong, Edward Dechaumphai, Courtney R. Green, Ratneshwar Lal, Anne N. Murphy, Christian M. Metallo, Renkun Chen
Published 2020-06-01

High throughput microplate respiratory measurements using minimal quantities of isolated mitochondria.

by George W Rogers, Martin D Brand, Susanna Petrosyan, Deepthi Ashok, Alvaro A Elorza, David A Ferrick, Anne N Murphy
Published 2011-01-01

Distinct Metabolic States Can Support Self-Renewal and Lipogenesis in Human Pluripotent Stem Cells under Different Culture Conditions

by Hui Zhang, Mehmet G. Badur, Ajit S. Divakaruni, Seth J. Parker, Christian Jäger, Karsten Hiller, Anne N. Murphy, Christian M. Metallo
Published 2016-08-01

Preserved cardiac function by vinculin enhances glucose oxidation and extends health- and life-span

by Ayla O. Sessions, Peter Min, Thekla Cordes, Barry J. Weickert, Ajit S. Divakaruni, Anne N. Murphy, Christian M. Metallo, Adam J. Engler
Published 2018-09-01

Deuterium‐Stabilized (R)‐Pioglitazone (PXL065) Is Responsible for Pioglitazone Efficacy in NASH yet Exhibits Little to No PPARγ Activity

by Vincent Jacques, Sébastien Bolze, Sophie Hallakou‐Bozec, Anthony W. Czarnik, Ajit S. Divakaruni, Pascale Fouqueray, Anne N. Murphy, Lex H.T. Van der Ploeg, Sheila DeWitt
Published 2021-08-01

HIV alters neuronal mitochondrial fission/fusion in the brain during HIV-associated neurocognitive disorders

by Jerel Adam Fields, Elisabeth Serger, Sofia Campos, Ajit S. Divakaruni, Changyoun Kim, Kendall Smith, Margarita Trejo, Anthony Adame, Brian Spencer, Edward Rockenstein, Anne N. Murphy, Ronald J. Ellis, Scott Letendre, Igor Grant, Eliezer Masliah
Published 2016-02-01

Mitochondrial biogenesis is altered in HIV+ brains exposed to ART: Implications for therapeutic targeting of astroglia

by Mary K. Swinton, Aliyah Carson, Francesca Telese, Ana B. Sanchez, Benchawanna Soontornniyomkij, Leila Rad, Isabella Batki, Brandi Quintanilla, Josué Pérez-Santiago, Cristian L. Achim, Scott Letendre, Ronald J. Ellis, Igor Grant, Anne N. Murphy, Jerel Adam Fields
Published 2019-10-01

Cardiac myosin inhibitor, CK-586, minimally reduces systolic function and ameliorates obstruction in feline hypertrophic cardiomyopathy

by Victor N. Rivas, Amanda E. Crofton, Carina E. Jauregui, Jalena R. Wouters, Betty S. Yang, Luke A. Wittenburg, Joanna L. Kaplan, Darren T. Hwee, Anne N. Murphy, Bradley P. Morgan, Fady I. Malik, Samantha P. Harris, Joshua A. Stern
Published 2024-05-01

Integrated In Vivo Quantitative Proteomics and Nutrient Tracing Reveals Age-Related Metabolic Rewiring of Pancreatic β Cell Function

by Matthew Wortham, Jacqueline R. Benthuysen, Martina Wallace, Jeffrey N. Savas, Francesca Mulas, Ajit S. Divakaruni, Fenfen Liu, Verena Albert, Brandon L. Taylor, Yinghui Sui, Enrique Saez, Anne N. Murphy, John R. Yates, III, Christian M. Metallo, Maike Sander
Published 2018-12-01

Identification of a mitochondrial target of thiazolidinedione insulin sensitizers (mTOT)--relationship to newly identified mitochondrial pyruvate carrier proteins.

by Jerry R Colca, William G McDonald, Gregory S Cavey, Serena L Cole, Danielle D Holewa, Angela S Brightwell-Conrad, Cindy L Wolfe, Jean S Wheeler, Kristin R Coulter, Peter M Kilkuskie, Elena Gracheva, Yulia Korshunova, Michelle Trusgnich, Robert Karr, Sandra E Wiley, Ajit S Divakaruni, Anne N Murphy, Patrick A Vigueira, Brian N Finck, Rolf F Kletzien
Published 2013-01-01

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases.

by Connolly, Niamh MC, Theurey, Pierre, Adam-Vizi, Vera, Bazan, Nicolas G, Bernardi, Paolo, Bolaños, Juan P, Culmsee, Carsten, Dawson, Valina L, Deshmukh, Mohanish, Duchen, Michael R, Düssmann, Heiko, Fiskum, Gary, Galindo, Maria F, Hardingham, Giles E, Hardwick, J Marie, Jekabsons, Mika B, Jonas, Elizabeth A, Jordán, Joaquin, Lipton, Stuart A, Manfredi, Giovanni, Mattson, Mark P, McLaughlin, BethAnn, Methner, Axel, Murphy, Anne N, Murphy, Michael P, Nicholls, David G, Polster, Brian M, Pozzan, Tullio, Rizzuto, Rosario, Satrústegui, Jorgina, Slack, Ruth S, Swanson, Raymond A, Swerdlow, Russell H, Will, Yvonne, Ying, Zheng, Joselin, Alvin, Gioran, Anna, Moreira Pinho, Catarina, Watters, Orla, Salvucci, Manuela, Llorente-Folch, Irene, Park, David S, Bano, Daniele, Ankarcrona, Maria, Pizzo, Paola, Prehn, Jochen HM
Published 2018