Deep Mining of Complex Antibody Phage Pools Generated by Cell Panning Enables Discovery of Rare Antibodies Binding New Targets and Epitopes

by Anne Ljungars, Anne Ljungars, Carolin Svensson, Anders Carlsson, Elin Birgersson, Ulla-Carin Tornberg, Björn Frendéus, Mats Ohlin, Mikael Mattsson
Published 2019-07-01

Towards better antivenoms: navigating the road to new types of snakebite envenoming therapies

by Suthimon Thumtecho, Nick J. Burlet, Anne Ljungars, Andreas H. Laustsen
Published 2023-12-01

From squid giant axon to automated patch-clamp: electrophysiology in venom and antivenom research

by Shirin Ahmadi, Melisa Benard-Valle, Kim Boddum, Fernanda C. Cardoso, Fernanda C. Cardoso, Glenn F. King, Glenn F. King, Andreas Hougaard Laustsen, Anne Ljungars
Published 2023-08-01

Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy

by Christoffer V. Sørensen, Line Ledsgaard, Helen H. K. Wildenauer, Camilla H. Dahl, Tasja W. Ebersole, Markus-Frederik Bohn, Anne Ljungars, Timothy P. Jenkins, Andreas H. Laustsen
Published 2023-06-01

Discovery and optimization of a broadly-neutralizing human monoclonal antibody against long-chain α-neurotoxins from snakes

by Line Ledsgaard, Jack Wade, Timothy P. Jenkins, Kim Boddum, Irina Oganesyan, Julian A. Harrison, Pedro Villar, Rachael A. Leah, Renato Zenobi, Sanne Schoffelen, Bjørn Voldborg, Anne Ljungars, John McCafferty, Bruno Lomonte, José M. Gutiérrez, Andreas H. Laustsen, Aneesh Karatt-Vellatt
Published 2023-02-01

Assessing developability early in the discovery process for novel biologics

by Monica L. Fernández-Quintero, Anne Ljungars, Franz Waibl, Victor Greiff, Jan Terje Andersen, Torleif T. Gjølberg, Timothy P. Jenkins, Bjørn Gunnar Voldborg, Lise Marie Grav, Sandeep Kumar, Guy Georges, Hubert Kettenberger, Klaus R. Liedl, Peter M. Tessier, John McCafferty, Andreas H. Laustsen
Published 2023-12-01

Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper

by Christoffer V. Sørensen, Julián Fernández, Anna Christina Adams, Helen H. K. Wildenauer, Sanne Schoffelen, Line Ledsgaard, Manuela B. Pucca, Michael Fiebig, Felipe A. Cerni, Tulika Tulika, Bjørn G. Voldborg, Aneesh Karatt-Vellatt, J. Preben Morth, Anne Ljungars, Lise M. Grav, Bruno Lomonte, Andreas H. Laustsen
Published 2024-01-01

In vivo neutralization of coral snake venoms with an oligoclonal nanobody mixture in a murine challenge model

by Melisa Benard-Valle, Yessica Wouters, Anne Ljungars, Giang Thi Tuyet Nguyen, Shirin Ahmadi, Tasja Wainani Ebersole, Camilla Holst Dahl, Alid Guadarrama-Martínez, Frederikke Jeppesen, Helena Eriksen, Gibran Rodríguez-Barrera, Kim Boddum, Timothy Patrick Jenkins, Sara Petersen Bjørn, Sanne Schoffelen, Bjørn Gunnar Voldborg, Alejandro Alagón, Andreas Hougaard Laustsen
Published 2024-05-01

LILRB3 (ILT5) is a myeloid cell checkpoint that elicits profound immunomodulation

by Muchaala Yeboah, Charys Papagregoriou, Des C. Jones, H.T. Claude Chan, Guangan Hu, Justine S. McPartlan, Torbjörn Schiött, Ulrika Mattson, C. Ian Mockridge, Ulla-Carin Tornberg, Björn Hambe, Anne Ljungars, Mikael Mattsson, Ivo Tews, Martin J. Glennie, Stephen M. Thirdborough, John Trowsdale, Björn Frendeus, Jianzhu Chen, Mark S. Cragg, Ali Roghanian
Published 2020-09-01