IGF1R Derived PI3K/AKT Signaling Maintains Growth in a Subset of Human T-Cell Acute Lymphoblastic Leukemias.

by Samuel Gusscott, Catherine E Jenkins, Sonya H Lam, Vincenzo Giambra, Michael Pollak, Andrew P Weng
Published 2016-01-01

RUNX1 colludes with NOTCH1 to reprogram chromatin in T cell acute lymphoblastic leukemia

by Rashedul Islam, Catherine E. Jenkins, Qi Cao, Jasper Wong, Misha Bilenky, Annaïck Carles, Michelle Moksa, Andrew P. Weng, Martin Hirst
Published 2023-06-01

Focused chemical genomics using zebrafish xenotransplantation as a pre-clinical therapeutic platform for T-cell acute lymphoblastic leukemia

by Victoria L. Bentley, Chansey J. Veinotte, Dale P. Corkery, Jordan B. Pinder, Marissa A. LeBlanc, Karen Bedard, Andrew P. Weng, Jason N. Berman, Graham Dellaire
Published 2015-01-01

Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene.

by Courteney K Lai, Yeonsook Moon, Florian Kuchenbauer, Daniel T Starzcynowski, Bob Argiropoulos, Eric Yung, Philip Beer, Adrian Schwarzer, Amit Sharma, Gyeongsin Park, Malina Leung, Grace Lin, Sarah Vollett, Stephen Fung, Connie J Eaves, Aly Karsan, Andrew P Weng, R Keith Humphries, Michael Heuser
Published 2014-01-01

Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia

by Manabu Kusakabe, Ann Chong Sun, Kateryna Tyshchenko, Rachel Wong, Aastha Nanda, Claire Shanna, Samuel Gusscott, Elizabeth A. Chavez, Alireza Lorzadeh, Alice Zhu, Ainsleigh Hill, Stacy Hung, Scott Brown, Artem Babaian, Xuehai Wang, Robert A. Holt, Christian Steidl, Aly Karsan, R. Keith Humphries, Connie J. Eaves, Martin Hirst, Andrew P. Weng
Published 2019-07-01

Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia.

by Gayle P Pouliot, James Degar, Laura Hinze, Bose Kochupurakkal, Chau D Vo, Melissa A Burns, Lisa Moreau, Chirag Ganesa, Justine Roderick, Sofie Peirs, Bjorn Menten, Mignon L Loh, Stephen P Hunger, Lewis B Silverman, Marian H Harris, Kristen E Stevenson, David M Weinstock, Andrew P Weng, Pieter Van Vlierberghe, Alan D D'Andrea, Alejandro Gutierrez
Published 2019-01-01

Single-cell profiling reveals a memory B cell-like subtype of follicular lymphoma with increased transformation risk

by Xuehai Wang, Michael Nissen, Deanne Gracias, Manabu Kusakabe, Guillermo Simkin, Aixiang Jiang, Gerben Duns, Clementine Sarkozy, Laura Hilton, Elizabeth A. Chavez, Gabriela C. Segat, Rachel Wong, Jubin Kim, Tomohiro Aoki, Rashedul Islam, Christina May, Stacy Hung, Kate Tyshchenko, Ryan R. Brinkman, Martin Hirst, Aly Karsan, Ciara Freeman, Laurie H. Sehn, Ryan D. Morin, Andrew J. Roth, Kerry J. Savage, Jeffrey W. Craig, Sohrab P. Shah, Christian Steidl, David W. Scott, Andrew P. Weng
Published 2022-11-01