Reconstructing cell cycle and disease progression using deep learning

by Philipp Eulenberg, Niklas Köhler, Thomas Blasi, Andrew Filby, Anne E. Carpenter, Paul Rees, Fabian J. Theis, F. Alexander Wolf
Published 2017-09-01

Stepwise B-cell-dependent expansion of T helper clonotypes diversifies the T-cell response

by Julia Merkenschlager, Mickaël J. Ploquin, Urszula Eksmond, Rakieb Andargachew, Georgina Thorborn, Andrew Filby, Marion Pepper, Brian Evavold, George Kassiotis
Published 2016-01-01

The trajectory of COVID-19 cardiopulmonary disease: insights from an autopsy study of community-based, pre-hospital deaths

by Luke Milross, Joaquim Majo, Julian Pulle, Sam Hoggard, Nigel Cooper, Bethany Hunter, Christopher J.A. Duncan, Andrew Filby, Andrew J. Fisher
Published 2022-12-01

Label-free cell cycle analysis for high-throughput imaging flow cytometry

by Thomas Blasi, Holger Hennig, Huw D. Summers, Fabian J. Theis, Joana Cerveira, James O. Patterson, Derek Davies, Andrew Filby, Anne E. Carpenter, Paul Rees
Published 2016-01-01

Multiple Immunostainings with Different Epitope Retrievals—The FOLGAS Protocol

by Anna von Schoenfeld, Peter Bronsert, Michael Poc, Andrew Fuller, Andrew Filby, Stefan Kraft, Konrad Kurowski, Kristin Sörensen, Julia Huber, Jens Pfeiffer, Michele Proietti, Verena Stehl, Martin Werner, Maximilian Seidl
Published 2021-12-01

Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace

by Laura Jardine, Sarah Wiscombe, Gary Reynolds, David McDonald, Andrew Fuller, Kile Green, Andrew Filby, Ian Forrest, Marie-Helene Ruchaud-Sparagano, Jonathan Scott, Matthew Collin, Muzlifah Haniffa, A. John Simpson
Published 2019-04-01

Hyperactive CREB subpopulations increase during therapy in pediatric B-lineage acute lymphoblastic leukemia

by Dino Masic, Kayleigh Fee, Hayden Bell, Marian Case, Gabby Witherington, Sophie Lansbury, Juan Ojeda-Garcia, David McDonald, Claire Schwab, Frederik W. van Delft, Andrew Filby, Julie Anne Elizabeth Irving
Published 2022-11-01

Imaging mass cytometry reveals generalised deficiency in OXPHOS complexes in Parkinson’s disease

by Chun Chen, David McDonald, Alasdair Blain, Ashwin Sachdeva, Laura Bone, Anna L. M. Smith, Charlotte Warren, Sarah J. Pickett, Gavin Hudson, Andrew Filby, Amy E. Vincent, Doug M. Turnbull, Amy K. Reeve
Published 2021-05-01

Parkinson’s disease neurons exhibit alterations in mitochondrial quality control proteins

by Chun Chen, David McDonald, Alasdair Blain, Emily Mossman, Kiera Atkin, Michael F. Marusich, Roderick Capaldi, Laura Bone, Anna Smith, Andrew Filby, Daniel Erskine, Oliver Russell, Gavin Hudson, Amy E. Vincent, Amy K. Reeve
Published 2023-08-01

Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission

by Kenneth F. Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel R. Schulz, Henrik E. Mei, Lucy MacDonald, Arthur G. Pratt, Andrew Filby, Amy E. Anderson, John D. Isaacs
Published 2024-02-01

Distinct lung cell signatures define the temporal evolution of diffuse alveolar damage in fatal COVID-19Research in context

by Luke Milross, Bethany Hunter, David McDonald, George Merces, Amanda Thomson, Catharien M.U. Hilkens, John Wills, Paul Rees, Kasim Jiwa, Nigel Cooper, Joaquim Majo, Helen Ashwin, Christopher J.A. Duncan, Paul M. Kaye, Omer Ali Bayraktar, Andrew Filby, Andrew J. Fisher
Published 2024-01-01

Role of immunosuppression in an antibiotic stewardship intervention and its association with clinical outcomes and antibiotic use: protocol for an observational study (RISC-sepsis)

by A John Simpson, Paul Dark, Katie Booth, Ranjit Lall, Gavin Perkins, Timothy Walsh, Manu Shankar-Hari, David McDonald, Daniel F McAuley, Andrew Conway Morris, Andrew Filby, Ronan McMullan, Thomas P Hellyer, Jonathan Scott, Loredana Trevi, Hannah McNeil, Tom Ewen, Phil Mawson, Gert Boschman, Vesna Melkebeek, Iain J McCullagh, Anthony Rostron
Published 2022-12-01

Imaging mass cytometry analysis of Becker muscular dystrophy muscle samples reveals different stages of muscle degeneration

by Patricia Piñol-Jurado, José Verdú-Díaz, Esther Fernández-Simón, Cristina Domínguez-González, Aurelio Hernández-Lain, Conor Lawless, Amy Vincent, Alejandro González-Chamorro, Elisa Villalobos, Alexandra Monceau, Zoe Laidler, Priyanka Mehra, James Clark, Andrew Filby, David McDonald, Paul Rushton, Andrew Bowey, Jorge Alonso Pérez, Giorgio Tasca, Chiara Marini-Bettolo, Michela Guglieri, Volker Straub, Xavier Suárez-Calvet, Jordi Díaz-Manera
Published 2024-02-01

A cell atlas of human thymic development defines T cell repertoire formation.

by Park, Jong-Eun, Botting, Rachel A, Domínguez Conde, Cecilia, Popescu, Dorin-Mirel, Lavaert, Marieke, Kunz, Daniel J, Goh, Issac, Stephenson, Emily, Ragazzini, Roberta, Tuck, Elizabeth, Wilbrey-Clark, Anna, Roberts, Kenny, Kedlian, Veronika R, Ferdinand, John R, He, Xiaoling, Webb, Simone, Maunder, Daniel, Vandamme, Niels, Mahbubani, Krishnaa T, Polanski, Krzysztof, Mamanova, Lira, Bolt, Liam, Crossland, David, de Rita, Fabrizio, Fuller, Andrew, Filby, Andrew, Reynolds, Gary, Dixon, David, Saeb-Parsy, Kourosh, Lisgo, Steven, Henderson, Deborah, Vento-Tormo, Roser, Bayraktar, Omer A, Barker, Roger A, Meyer, Kerstin B, Saeys, Yvan, Bonfanti, Paola, Behjati, Sam, Clatworthy, Menna R, Taghon, Tom, Haniffa, Muzlifah, Teichmann, Sarah A
Published 2020