Development and Preclinical Evaluation of an Integrase Defective Lentiviral Vector Vaccine Expressing the HIVACAT T Cell Immunogen in Mice

by Alessandra Gallinaro, Martina Borghi, Maria Franca Pirillo, Serena Cecchetti, Roberta Bona, Andrea Canitano, Zuleika Michelini, Antonio Di Virgilio, Alex Olvera, Christian Brander, Donatella Negri, Andrea Cara
Published 2020-06-01

Functional diversification of innate and inflammatory immune responses mediated by antibody fragment crystallizable activities against SARS-CoV-2

by Martina Severa, Marilena Paola Etna, Emanuele Andreano, Daniela Ricci, Giada Cairo, Stefano Fiore, Andrea Canitano, Andrea Cara, Paola Stefanelli, Rino Rappuoli, Anna Teresa Palamara, Eliana Marina Coccia
Published 2024-05-01

Safety and efficiency modifications of SIV-based integrase-defective lentiviral vectors for immunization

by Roberta Bona, Zuleika Michelini, Chiara Mazzei, Alessandra Gallinaro, Andrea Canitano, Martina Borghi, Maria Fenicia Vescio, Antonio Di Virgilio, Maria Franca Pirillo, Mary E. Klotman, Donatella Negri, Andrea Cara
Published 2021-12-01

Integrase-Defective Lentiviral Vector Is an Efficient Vaccine Platform for Cancer Immunotherapy

by Valeria Morante, Martina Borghi, Iole Farina, Zuleika Michelini, Felicia Grasso, Alessandra Gallinaro, Serena Cecchetti, Antonio Di Virgilio, Andrea Canitano, Maria Franca Pirillo, Roberta Bona, Andrea Cara, Donatella Negri
Published 2021-02-01

Integrase Defective Lentiviral Vector as a Vaccine Platform for Delivering Influenza Antigens

by Alessandra Gallinaro, Martina Borghi, Roberta Bona, Felicia Grasso, Laura Calzoletti, Laura Palladino, Serena Cecchetti, Maria Fenicia Vescio, Daniele Macchia, Valeria Morante, Andrea Canitano, Nigel Temperton, Maria Rita Castrucci, Mirella Salvatore, Zuleika Michelini, Andrea Cara, Donatella Negri
Published 2018-02-01

Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival

by Stefania Dispinseri, Massimiliano Secchi, Maria Franca Pirillo, Monica Tolazzi, Martina Borghi, Cristina Brigatti, Maria Laura De Angelis, Marco Baratella, Elena Bazzigaluppi, Giulietta Venturi, Francesca Sironi, Andrea Canitano, Ilaria Marzinotto, Cristina Tresoldi, Fabio Ciceri, Lorenzo Piemonti, Donatella Negri, Andrea Cara, Vito Lampasona, Gabriella Scarlatti
Published 2021-05-01

Different configurations of SARS-CoV-2 spike protein delivered by integrase-defective lentiviral vectors induce persistent functional immune responses, characterized by distinct im...

by Martina Borghi, Alessandra Gallinaro, Maria Franca Pirillo, Andrea Canitano, Zuleika Michelini, Maria Laura De Angelis, Serena Cecchetti, Antonella Tinari, Chiara Falce, Sabrina Mariotti, Antonio Capocefalo, Maria Vincenza Chiantore, Angelo Iacobino, Antonio Di Virgilio, Marit J. van Gils, Rogier W. Sanders, Alessandra Lo Presti, Roberto Nisini, Donatella Negri, Andrea Cara
Published 2023-04-01

Persistent immunogenicity of integrase defective lentiviral vectors delivering membrane-tethered native-like HIV-1 envelope trimers

by Alessandra Gallinaro, Maria Franca Pirillo, Yoann Aldon, Serena Cecchetti, Zuleika Michelini, Antonella Tinari, Martina Borghi, Andrea Canitano, Paul F. McKay, Roberta Bona, Maria Fenicia Vescio, Felicia Grasso, Maria Blasi, Silvia Baroncelli, Gabriella Scarlatti, Celia LaBranche, David Montefiori, Mary E. Klotman, Rogier W. Sanders, Robin J. Shattock, Donatella Negri, Andrea Cara
Published 2022-04-01

Isolation and Characterization of Mouse Monoclonal Antibodies That Neutralize SARS-CoV-2 and Its Variants of Concern Alpha, Beta, Gamma and Delta by Binding Conformational Epitopes...

by Sabrina Mariotti, Antonio Capocefalo, Maria Vincenza Chiantore, Angelo Iacobino, Raffaela Teloni, Maria Laura De Angelis, Alessandra Gallinaro, Maria Franca Pirillo, Martina Borghi, Andrea Canitano, Zuleika Michelini, Melissa Baggieri, Antonella Marchi, Paola Bucci, Paul F. McKay, Chiara Acchioni, Silvia Sandini, Marco Sgarbanti, Fabio Tosini, Antonio Di Virgilio, Giulietta Venturi, Francesco Marino, Valeria Esposito, Paola Di Bonito, Fabio Magurano, Andrea Cara, Donatella Negri, Roberto Nisini
Published 2021-10-01