Role of Fiber Shaft Length in Tumor Targeting with Ad5/3 Vectors

by Maximilian Richter, Hongjie Wang, André Lieber
Published 2022-11-01

HDAd5/35++ Adenovirus Vector Expressing Anti-CRISPR Peptides Decreases CRISPR/Cas9 Toxicity in Human Hematopoietic Stem Cells

by Chang Li, Nikoletta Psatha, Sucheol Gil, Hongjie Wang, Thalia Papayannopoulou, André Lieber
Published 2018-06-01

CD46 and CD59 inhibitors enhance complement-dependent cytotoxicity of anti-CD38 monoclonal antibodies daratumumab and isatuximab in multiple myeloma and other B-cell malignancy cel...

by Hongjie Wang, Theo Koob, Jonathan R. Fromm, Ajay Gopal, Darrick Carter, André Lieber
Published 2024-12-01

HDAd6/35++ - A new helper-dependent adenovirus vector platform for in vivo transduction of hematopoietic stem cells

by Hongjie Wang, Aphrodite Georgakopoulou, Wenli Zhang, Jiho Kim, Sucheol Gil, Anja Ehrhardt, André Lieber
Published 2023-06-01

Method for Multiple Portal Vein Infusions in Mice: Quantitation of Adenovirus-Mediated Hepatic Gene Transfer

by Marie-Jeanne T.F.D. Vrancken Peeters, Andre Lieber, James Perkins, Mark A. Kay
Published 1996-02-01

P317: Gene therapy base editors reshape single-molecule chromatin architecture of γ-globin promoters

by Stephanie Bohaczuk, Chang Li, Danilo Dubocanin, Ben Mallory, Mitchell Vollger, Andre Lieber, Andrew Stergachis
Published 2023-01-01

Quantification of designer nuclease induced mutation rates: a direct comparison of different methods

by Eric Ehrke-Schulz, Thorsten Bergmann, Maren Schiwon, Johannes Doerner, Kamola Saydaminova, Andre Lieber, Anja Ehrhardt
Published 2016-01-01

Role of cellular heparan sulfate proteoglycans in infection of human adenovirus serotype 3 and 35.

by Sebastian Tuve, Hongjie Wang, Jeffrey D Jacobs, Roma C Yumul, David F Smith, André Lieber
Published 2008-10-01

Penton-dodecahedral particles trigger opening of intercellular junctions and facilitate viral spread during adenovirus serotype 3 infection of epithelial cells.

by Zhuo-Zhuang Lu, Hongjie Wang, Yiyi Zhang, Hua Cao, Zongyi Li, Pascal Fender, André Lieber
Published 2013-10-01

Immuno-therapy with anti-CTLA4 antibodies in tolerized and non-tolerized mouse tumor models.

by Jonas Persson, Ines Beyer, Roma Yumul, ZongYi Li, Hans-Peter Kiem, Steve Roffler, André Lieber
Published 2011-01-01

Binding Mechanism Elucidation of the Acute Respiratory Disease Causing Agent Adenovirus of Serotype 7 to Desmoglein-2

by Marc-André Hograindleur, Gregory Effantin, Daphna Fenel, Caroline Mas, André Lieber, Guy Schoehn, Pascal Fender, Emilie Vassal-Stermann
Published 2020-09-01

CryoEM structure of adenovirus type 3 fibre with desmoglein 2 shows an unusual mode of receptor engagement

by Emilie Vassal-Stermann, Gregory Effantin, Chloe Zubieta, Wim Burmeister, Frédéric Iseni, Hongjie Wang, André Lieber, Guy Schoehn, Pascal Fender
Published 2019-03-01

Integrating HDAd5/35++ Vectors as a New Platform for HSC Gene Therapy of Hemoglobinopathies

by Chang Li, Nikoletta Psatha, Hongjie Wang, Manvendra Singh, Himanshu Bhusan Samal, Wenli Zhang, Anja Ehrhardt, Zsuzsanna Izsvák, Thalia Papayannopoulou, André Lieber
Published 2018-06-01

Two types of functionally distinct fiber containing structural protein complexes are produced during infection of adenovirus serotype 5.

by Bo Zhang, Yuhua Yan, Jie Jin, Hongyu Lin, Zongyi Li, Xiaoyan Zhang, Jin Liu, Chao Xi, Andre Lieber, Xiaolong Fan, Liang Ran
Published 2015-01-01

Properties of Adenovirus Vectors with Increased Affinity to DSG2 and the Potential Benefits of Oncolytic Approaches and Gene Therapy

by Nora A. Bahlmann, Raphael L. Tsoukas, Sebastian Erkens, Hongjie Wang, Franziska Jönsson, Malik Aydin, Ella A. Naumova, André Lieber, Anja Ehrhardt, Wenli Zhang
Published 2022-08-01

Curative in vivo hematopoietic stem cell gene therapy of murine thalassemia using large regulatory elements

by Hongjie Wang, Aphrodite Georgakopoulou, Chang Li, Zhinan Liu, Sucheol Gil, Ashvin Bashyam, Evangelia Yannaki, Achilles Anagnostopoulos, Amit Pande, Zsuzsanna Izsvák, Thalia Papayannopoulou, André Lieber
Published 2020-08-01

Preclinical Safety Studies of Enadenotucirev, a Chimeric Group B Human-Specific Oncolytic Adenovirus

by Sam Illingworth, Ying Di, Maxine Bauzon, Janet Lei, Margaret R. Duffy, Simon Alvis, Brian Champion, André Lieber, Terry Hermiston, Len W. Seymour, John Beadle, Kerry Fisher
Published 2017-06-01

CD40L coding oncolytic adenovirus allows long-term survival of humanized mice receiving dendritic cell therapy

by Sadia Zafar, Suvi Sorsa, Mikko Siurala, Otto Hemminki, Riikka Havunen, Victor Cervera-Carrascon, João Manuel Santos, Hongjie Wang, Andre Lieber, Tanja De Gruijl, Anna Kanerva, Akseli Hemminki
Published 2018-10-01

Analysis of epithelial and mesenchymal markers in ovarian cancer reveals phenotypic heterogeneity and plasticity.

by Robert Strauss, Zong-Yi Li, Ying Liu, Ines Beyer, Jonas Persson, Pavel Sova, Thomas Möller, Sari Pesonen, Akseli Hemminki, Petra Hamerlik, Charles Drescher, Nicole Urban, Jiri Bartek, André Lieber
Published 2011-01-01

Intravenously usable fully serotype 3 oncolytic adenovirus coding for CD40L as an enabler of dendritic cell therapy

by Sadia Zafar, Suvi Parviainen, Mikko Siurala, Otto Hemminki, Riikka Havunen, Siri Tähtinen, Simona Bramante, Lotta Vassilev, Hongjie Wang, Andre Lieber, Silvio Hemmi, Tanja de Gruijl, Anna Kanerva, Akseli Hemminki
Published 2017-02-01