Physiologically Based Pharmacokinetic Modeling in Pregnancy, during Lactation and in Neonates: Achievements, Challenges and Future Directions

by Karel Allegaert, Sara K. Quinney, André Dallmann
Published 2024-04-01

Applied Concepts in PBPK Modeling: How to Extend an Open Systems Pharmacology Model to the Special Population of Pregnant Women

by André Dallmann, Juri Solodenko, Ibrahim Ince, Thomas Eissing
Published 2018-07-01

Editorial: Exploring Maternal-Fetal Pharmacology Through PBPK Modeling Approaches

by André Dallmann, John N. van den Anker, John N. van den Anker
Published 2022-05-01

Physiologically Based Pharmacokinetic Modeling in Pregnant Women Suggests Minor Decrease in Maternal Exposure to Olanzapine

by Liang Zheng, Liang Zheng, Hongyi Yang, André Dallmann, Xuehua Jiang, Ling Wang, Wei Hu
Published 2022-01-01

Aptamer BC 007’s Affinity to Specific and Less-Specific Anti-SARS-CoV-2 Neutralizing Antibodies

by Annekathrin Haberland, Oxana Krylova, Heike Nikolenko, Peter Göttel, Andre Dallmann, Johannes Müller, Hardy Weisshoff
Published 2021-05-01

A generic framework for the physiologically‐based pharmacokinetic platform qualification of PK‐Sim and its application to predicting cytochrome P450 3A4–mediated drug–drug interact...

by Sebastian Frechen, Juri Solodenko, Thomas Wendl, André Dallmann, Ibrahim Ince, Thorsten Lehr, Jörg Lippert, Rolf Burghaus
Published 2021-06-01

Modelling Tools to Characterize Acetaminophen Pharmacokinetics in the Pregnant Population

by Sofie A. M. Brookhuis, Karel Allegaert, Lidwien M. Hanff, Marjolijn N. Lub-de Hooge, André Dallmann, Paola Mian
Published 2021-08-01

Aptamer BC 007 - Efficient binder of spreading-crucial SARS-CoV-2 proteins

by Hardy Weisshoff, Oxana Krylova, Heike Nikolenko, Hans-Dirk Düngen, Andre Dallmann, Susanne Becker, Peter Göttel, Johannes Müller, Annekathrin Haberland
Published 2020-11-01

Applied physiologically‐based pharmacokinetic modeling to assess uridine diphosphate‐glucuronosyltransferase‐mediated drug–drug interactions for Vericiguat

by Sebastian Frechen, Ibrahim Ince, André Dallmann, Michael Gerisch, Natalia A. Jungmann, Corina Becker, Maximilian Lobmeyer, Maria E. Trujillo, Shiyao Xu, Rolf Burghaus, Michaela Meyer
Published 2024-01-01

Physiologically‐based pharmacokinetic modeling of remdesivir and its metabolites in pregnant women with COVID‐19

by Xiaomei I. Liu, André Dallmann, Kristina Brooks, Brookie M. Best, Diana F. Clarke, Mark Mirochnick, John N. van denAnker, Edmund V. Capparelli, Jeremiah D. Momper
Published 2023-02-01

A cryptic RNA-binding domain mediates Syncrip recognition and exosomal partitioning of miRNA targets

by Fruzsina Hobor, Andre Dallmann, Neil J. Ball, Carla Cicchini, Cecilia Battistelli, Roksana W. Ogrodowicz, Evangelos Christodoulou, Stephen R. Martin, Alfredo Castello, Marco Tripodi, Ian A. Taylor, Andres Ramos
Published 2018-02-01

Structural basis for terminal loop recognition and stimulation of pri-miRNA-18a processing by hnRNP A1

by Hamed Kooshapur, Nila Roy Choudhury, Bernd Simon, Max Mühlbauer, Alexander Jussupow, Noemi Fernandez, Alisha N. Jones, Andre Dallmann, Frank Gabel, Carlo Camilloni, Gracjan Michlewski, Javier F. Caceres, Michael Sattler
Published 2018-06-01

Mechanistic Modeling of Placental Drug Transfer in Humans: How Do Differences in Maternal/Fetal Fraction of Unbound Drug and Placental Influx/Efflux Transfer Rates Affect Fetal Pha...

by Xiaomei I. Liu, Dionna J. Green, John N. van den Anker, Natella Y. Rakhmanina, Natella Y. Rakhmanina, Homa K. Ahmadzia, Jeremiah D. Momper, Kyunghun Park, Gilbert J. Burckart, André Dallmann
Published 2021-10-01

Mechanistic Coupling of a Novel in silico Cotyledon Perfusion Model and a Physiologically Based Pharmacokinetic Model to Predict Fetal Acetaminophen Pharmacokinetics at Delivery

by Paola Mian, Bridget Nolan, Bridget Nolan, John N. van den Anker, John N. van den Anker, Kristel van Calsteren, Kristel van Calsteren, Karel Allegaert, Karel Allegaert, Karel Allegaert, Nisha Lakhi, Nisha Lakhi, André Dallmann
Published 2021-09-01