Bioprocessing Considerations towards the Manufacturing of Therapeutic Skeletal and Smooth Muscle Cells

by Teresa Franchi-Mendes, Marília Silva, Ana Luísa Cartaxo, Ana Fernandes-Platzgummer, Joaquim M. S. Cabral, Cláudia L. da Silva
Published 2023-09-01

Advances in ex vivo expansion of hematopoietic stem and progenitor cells for clinical applications

by André Branco, André Branco, Janakiram Rayabaram, Cláudia C. Miranda, Cláudia C. Miranda, Cláudia C. Miranda, Ana Fernandes-Platzgummer, Ana Fernandes-Platzgummer, Tiago G. Fernandes, Tiago G. Fernandes, Suchitra Sajja, Cláudia L. da Silva, Cláudia L. da Silva, Mohan C. Vemuri
Published 2024-05-01

Tailored Cytokine Optimization for ex vivo Culture Platforms Targeting the Expansion of Human Hematopoietic Stem/Progenitor Cells

by André Branco, Sara Bucar, Jorge Moura-Sampaio, Carla Lilaia, Joaquim M. S. Cabral, Ana Fernandes-Platzgummer, Cláudia Lobato da Silva
Published 2020-09-01

From Promise to Reality: Bioengineering Strategies to Enhance the Therapeutic Potential of Extracellular Vesicles

by Miguel de Almeida Fuzeta, Pedro P. Gonçalves, Ana Fernandes-Platzgummer, Joaquim M. S. Cabral, Nuno Bernardes, Cláudia L. da Silva
Published 2022-11-01

Influence of the mesenchymal stromal cell source on the hematopoietic supportive capacity of umbilical cord blood-derived CD34+-enriched cells

by Sara Bucar, André Dargen de Matos Branco, Márcia F. Mata, João Coutinho Milhano, Íris Caramalho, Joaquim M. S. Cabral, Ana Fernandes-Platzgummer, Cláudia L. da Silva
Published 2021-07-01

Hypothermic Preservation of Adipose-Derived Mesenchymal Stromal Cells as a Viable Solution for the Storage and Distribution of Cell Therapy Products

by André Branco, Ana L. Tiago, Paula Laranjeira, Maria C. Carreira, João C. Milhano, Francisco dos Santos, Joaquim M. S. Cabral, Artur Paiva, Cláudia L. da Silva, Ana Fernandes-Platzgummer
Published 2022-12-01

Neurodifferentiation and Neuroprotection Potential of Mesenchymal Stromal Cell-Derived Secretome Produced in Different Dynamic Systems

by Cláudia Raquel Marques, Miguel de Almeida Fuzeta, Raquel Medina dos Santos Cunha, Joana Pereira-Sousa, Deolinda Silva, Jonas Campos, Andreia Teixeira-Castro, Rui Amandi Sousa, Ana Fernandes-Platzgummer, Cláudia L. da Silva, António José Salgado
Published 2023-04-01

Scalable Production of Human Mesenchymal Stromal Cell-Derived Extracellular Vesicles Under Serum-/Xeno-Free Conditions in a Microcarrier-Based Bioreactor Culture System

by Miguel de Almeida Fuzeta, Miguel de Almeida Fuzeta, Nuno Bernardes, Filipa D. Oliveira, Ana Catarina Costa, Ana Fernandes-Platzgummer, José Paulo Farinha, Carlos A. V. Rodrigues, Sunghoon Jung, Rong-Jeng Tseng, William Milligan, Brian Lee, Miguel A. R. B. Castanho, Diana Gaspar, Joaquim M. S. Cabral, Cláudia Lobato da Silva
Published 2020-11-01