Developing <i>In Vitro</i> Models to Define the Role of Direct Mitochondrial Toxicity in Frequently Reported Drug-Induced Rhabdomyolysis

by Faten F. Bin Dayel, Ana Alfirevic, Amy E. Chadwick
Published 2023-05-01

The mitochondrial paradox

by Sophie L Penman, Rebecca L Jensen, Robyn T Kiy, Amy E Chadwick
Published 2020-06-01

The Role of Mitochondrial DNA Variation in Drug Response: A Systematic Review

by Samantha W. Jones, Amy L. Ball, Amy E. Chadwick, Ana Alfirevic
Published 2021-08-01

Bioenergetic profile of human coronary artery smooth muscle cells and effect of metabolic intervention.

by Mingming Yang, Amy E Chadwick, Caroline Dart, Tomoko Kamishima, John M Quayle
Published 2017-01-01

Using the health belief model to identify communication opportunities to prevent Chagas disease in Southern Ecuador.

by Nelson M Patterson, Benjamin R Bates, Amy E Chadwick, Claudia Nieto-Sanchez, Mario J Grijalva
Published 2018-09-01

The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury

by Amy Louise Ball, Carol E Jolly, Mark G Lennon, Jonathan J Lyon, Ana Alfirevic, Amy E Chadwick
Published 2023-06-01

Modelling the impact of changes in the extracellular environment on the cytosolic free NAD+/NADH ratio during cell culture.

by Ross A Kelly, Joseph Leedale, Andy Harrell, Daniel A Beard, Laura E Randle, Amy E Chadwick, Steven D Webb
Published 2018-01-01

Exposure of human immune cells, to the antiretrovirals efavirenz and lopinavir, leads to lower glucose uptake and altered bioenergetic cell profiles through interactions with SLC2A...

by Bethany J. Heaton, Rebecca L. Jensen, James Line, Christopher A.W. David, Danielle E. Brain, Amy E. Chadwick, Neill J. Liptrott
Published 2022-06-01

Selective protein kinase C inhibition switches time-dependent glucose cardiotoxicity to cardioprotection

by Sean Brennan, Simona Esposito, Simona Esposito, Muhammad I. M. Abdelaziz, Christopher A. Martin, Samir Makwana, Mark W. Sims, Iain B. Squire, Iain B. Squire, Parveen Sharma, Amy E. Chadwick, Richard D. Rainbow
Published 2022-09-01