Genetic and pharmacological tools to study the role of discoidin domain receptors in kidney disease

by Corina M. Borza, Gema Bolas, Ambra Pozzi, Ambra Pozzi
Published 2022-09-01

PPARα Ligands as Antitumorigenic and Antiangiogenic Agents

by Ambra Pozzi, Jorge H. Capdevila
Published 2008-01-01

Quantitative Structure–Activity Relationship Modeling of Kinase Selectivity Profiles

by Sandeepkumar Kothiwale, Corina Borza, Ambra Pozzi, Jens Meiler
Published 2017-09-01

CD98 increases renal epithelial cell proliferation by activating MAPKs.

by Nada Bulus, Chloe Feral, Ambra Pozzi, Roy Zent
Published 2012-01-01

Sexual dimorphism in reactive oxygen species production and a role for integrin α1β1 in estrogen receptor α and β expression in articular cartilage

by Alicia L. Black, James Haskins, Ambra Pozzi, Andrea L. Clark
Published 2023-03-01

Depleting transforming growth factor beta receptor 2 signalling in the cartilage of itga1-null mice attenuates spontaneous knee osteoarthritis

by Jennifer St Amant, Jana Michaud, Daniel Hinds, Madison Coyle, Ambra Pozzi, Andrea L. Clark
Published 2023-12-01

Inhibition of 11β-Hydroxysteroid Dehydrogenase Type II Suppresses Lung Carcinogenesis by Blocking Tumor COX-2 Expression as Well as the ERK and mTOR Signaling Pathways.

by Jian Chang, Min Xue, Shilin Yang, Bing Yao, Bixiang Zhang, Xiaoping Chen, Ambra Pozzi, Ming-Zhi Zhang
Published 2015-01-01

Genetic variation in the eicosanoid pathway is associated with non-small-cell lung cancer (NSCLC) survival.

by Lindsay N Sausville, Carissa C Jones, Melinda C Aldrich, William J Blot, Ambra Pozzi, Scott M Williams
Published 2017-01-01

Implications of the differing roles of the β1 and β3 transmembrane and cytoplasmic domains for integrin function

by Zhenwei Lu, Sijo Mathew, Jiang Chen, Arina Hadziselimovic, Riya Palamuttam, Billy G Hudson, Reinhard Fässler, Ambra Pozzi, Charles R Sanders, Roy Zent
Published 2016-12-01

Membrane-type 4 matrix metalloproteinase (MT4-MMP) modulates water homeostasis in mice.

by Manakan B Srichai, Heloisa Colleta, Leslie Gewin, Linsey Matrisian, Ty W Abel, Naohiko Koshikawa, Motoharu Seiki, Ambra Pozzi, Raymond C Harris, Roy Zent
Published 2011-02-01

Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation

by Kensei Taguchi, Bertha C. Elias, Sho Sugahara, Snehal Sant, Benjamin S. Freedman, Sushrut S. Waikar, Ambra Pozzi, Roy Zent, Raymond C. Harris, Samir M. Parikh, Craig R. Brooks
Published 2022-12-01

Matrix protein Tenascin-C promotes kidney fibrosis via STAT3 activation in response to tubular injury

by Qionghong Xie, Min Zhang, Xiaoyi Mao, Mingyue Xu, Shaojun Liu, Da Shang, Yunyu Xu, Ruiying Chen, Yi Guan, Xinzhong Huang, Roy Zent, Ambra Pozzi, Chuan-Ming Hao
Published 2022-12-01

The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation

by Corina M. Borza, Gema Bolas, Xiuqi Zhang, Mary Beth Browning Monroe, Ming-Zhi Zhang, Jens Meiler, Jens Meiler, Marcin J. Skwark, Raymond C. Harris, Lynne A. Lapierre, Lynne A. Lapierre, James R. Goldenring, James R. Goldenring, James R. Goldenring, Magnus Hook, Jose Rivera, Kyle L. Brown, Birgit Leitinger, Matthew J. Tyska, Markus Moser, Ralph T. Böttcher, Roy Zent, Roy Zent, Roy Zent, Ambra Pozzi, Ambra Pozzi
Published 2022-03-01

DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3

by Corina M. Borza, Gema Bolas, Fabian Bock, Xiuqi Zhang, Favour C. Akabogu, Ming-Zhi Zhang, Mark de Caestecker, Min Yang, Haichun Yang, Ethan Lee, Leslie Gewin, Agnes B. Fogo, W. Hayes McDonald, Roy Zent, Ambra Pozzi
Published 2022-02-01

Ligand-independent integrin β1 signaling supports lung adenocarcinoma development

by Scott M. Haake, Erin J. Plosa, Jonathan A. Kropski, Lindsay A. Venton, Anupama Reddy, Fabian Bock, Betty T. Chang, Allen J. Luna, Kateryna Nabukhotna, Zhi-Qi Xu, Rebecca A. Prather, Sharon Lee, Harikrishna Tanjore, Vasiliy V. Polosukhin, Olga M. Viquez, Angela Jones, Wentian Luo, Matthew H. Wilson, W. Kimryn Rathmell, Pierre P. Massion, Ambra Pozzi, Timothy S. Blackwell, Roy Zent
Published 2022-08-01