Small molecule induced polymerization of BCL6 facilitates SIAH1 mediated degradation

by Sandeep Rana, Amarnath Natarajan
Published 2021-04-01

PROTACs in Ovarian Cancer: Current Advancements and Future Perspectives

by Makenzie Vorderbruggen, Carlos A. Velázquez-Martínez, Amarnath Natarajan, Adam R. Karpf
Published 2024-05-01

Inhibitors, PROTACs and Molecular Glues as Diverse Therapeutic Modalities to Target Cyclin-Dependent Kinase

by Sandeep Rana, Jayapal Reddy Mallareddy, Sarbjit Singh, Lidia Boghean, Amarnath Natarajan
Published 2021-11-01

Identification of the DNA-Binding Domains of Human Replication Protein A That Recognize G-Quadruplex DNA

by Aishwarya Prakash, Amarnath Natarajan, Luis A. Marky, Michel M. Ouellette, Gloria E. O. Borgstahl
Published 2011-01-01

Recent Advances in EPAC-Targeted Therapies: A Biophysical Perspective

by Alveena Ahmed, Stephen Boulton, Hongzhao Shao, Madoka Akimoto, Amarnath Natarajan, Xiaodong Cheng, Giuseppe Melacini
Published 2019-11-01

Characterization of Promiscuous Binding of Phosphor Ligands to Breast-Cancer-Gene 1 (BRCA1) C-Terminal (BRCT): Molecular Dynamics, Free Energy, Entropy and Inhibitor Design.

by Wanli You, Yu-Ming M Huang, Smitha Kizhake, Amarnath Natarajan, Chia-En A Chang
Published 2016-08-01

PIK3C3 Inhibition Promotes Sensitivity to Colon Cancer Therapy by Inhibiting Cancer Stem Cells

by Balawant Kumar, Rizwan Ahmad, Swagat Sharma, Saiprasad Gowrikumar, Mark Primeaux, Sandeep Rana, Amarnath Natarajan, David Oupicky, Corey R. Hopkins, Punita Dhawan, Amar B. Singh
Published 2021-04-01

Selective killing of homologous recombination-deficient cancer cell lines by inhibitors of the RPA:RAD52 protein-protein interaction.

by Mona Al-Mugotir, Jeffrey J Lovelace, Joseph George, Mika Bessho, Dhananjaya Pal, Lucas Struble, Carol Kolar, Sandeep Rana, Amarnath Natarajan, Tadayoshi Bessho, Gloria E O Borgstahl
Published 2021-01-01

Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions

by Pawel Nowialis, Katarina Lopusna, Jana Opavska, Staci L. Haney, Ajay Abraham, Peike Sheng, Alberto Riva, Amarnath Natarajan, Olga Guryanova, Melanie Simpson, Ryan Hlady, Mingyi Xie, Rene Opavsky
Published 2019-09-01

Systemic Administration of a Brain Permeable Cdk5 Inhibitor Alters Neurobehavior

by Alan Umfress, Sarbjit Singh, Kevin J. Ryan, Ayanabha Chakraborti, Florian Plattner, Yogesh Sonawane, Jayapal Reddy Mallareddy, Edward P. Acosta, Amarnath Natarajan, James A. Bibb, James A. Bibb, James A. Bibb
Published 2022-05-01

A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1

by Xiao-Feng Zheng, Sanket S. Acharya, Katherine N. Choe, Kumar Nikhil, Guillaume Adelmant, Shakti Ranjan Satapathy, Samanta Sharma, Keith Viccaro, Sandeep Rana, Amarnath Natarajan, Peter Sicinski, Jarrod A. Marto, Kavita Shah, Dipanjan Chowdhury
Published 2019-09-01

Cdk5 mediates rotational force-induced brain injury

by Alan Umfress, Ayanabha Chakraborti, Suma Priya Sudarsana Devi, Raegan Adams, Daniel Epstein, Adriana Massicano, Anna Sorace, Sarbjit Singh, M. Iqbal Hossian, Shaida A. Andrabi, David K. Crossman, Nilesh Kumar, M. Shahid Mukhtar, Huiyang Luo, Claire Simpson, Kathryn Abell, Matthew Stokes, Thorsten Wiederhold, Charles Rosen, Hongbing Lu, Amarnath Natarajan, James A. Bibb
Published 2023-02-01

GD2 and its biosynthetic enzyme GD3 synthase promote tumorigenesis in prostate cancer by regulating cancer stem cell behavior

by Aaqib M. Bhat, Bhopal C. Mohapatra, Haitao Luan, Insha Mushtaq, Sukanya Chakraborty, Siddhartha Kumar, Wangbin Wu, Ben Nolan, Samikshan Dutta, Matthew D. Storck, Micah Schott, Jane L. Meza, Subodh M. Lele, Ming-Fong Lin, Leah M. Cook, Eva Corey, Colm Morrissey, Donald W. Coulter, M. Jordan Rowley, Amarnath Natarajan, Kaustubh Datta, Vimla Band, Hamid Band
Published 2024-06-01

Mutant Cbl Proteins as Oncogenic Drivers in Myeloproliferative Disorders

by Naramura, Mayumi, Nadeau, Scott, Mohapatra, Bhopal, Ahmad, Gulzar, Mukhopadhyay, Chandrani, Raja, Srikumar M, Natarajan, Amarnath, Band, Vimla, Band, Hamid, Sattler, Martin
Published 2012