High-throughput interrogation of immune responses using the Human Immune Profiling Pipeline

by Guanning Wang, Olga Lyudovyk, Justin Y. Kim, Ya-Hui Lin, Yuval Elhanati, Divij Mathew, E. John Wherry, Ramin S. Herati, Allison R. Greenplate, Benjamin Greenbaum, Santosha A. Vardhana, Alexander C. Huang
Published 2023-06-01

Unsupervised machine learning reveals risk stratifying glioblastoma tumor cells

by Nalin Leelatian, Justine Sinnaeve, Akshitkumar M Mistry, Sierra M Barone, Asa A Brockman, Kirsten E Diggins, Allison R Greenplate, Kyle D Weaver, Reid C Thompson, Lola B Chambless, Bret C Mobley, Rebecca A Ihrie, Jonathan M Irish
Published 2020-06-01

An extended SARS-CoV-2 mRNA vaccine prime-boost interval enhances B cell immunity with limited impact on T cells

by Alexandre Nicolas, Gérémy Sannier, Mathieu Dubé, Manon Nayrac, Alexandra Tauzin, Mark M. Painter, Rishi R. Goel, Mélanie Laporte, Gabrielle Gendron-Lepage, Halima Medjahed, Justine C. Williams, Nathalie Brassard, Julia Niessl, Laurie Gokool, Chantal Morrisseau, Pascale Arlotto, Cécile Tremblay, Valérie Martel-Laferrière, Andrés Finzi, Allison R. Greenplate, E. John Wherry, Daniel E. Kaufmann
Published 2023-01-01

Melanoma-specific MHC-II expression represents a tumour-autonomous phenotype and predicts response to anti-PD-1/PD-L1 therapy

by Douglas B. Johnson, Monica V. Estrada, Roberto Salgado, Violeta Sanchez, Deon B. Doxie, Susan R. Opalenik, Anna E. Vilgelm, Emily Feld, Adam S. Johnson, Allison R. Greenplate, Melinda E. Sanders, Christine M. Lovly, Dennie T. Frederick, Mark C. Kelley, Ann Richmond, Jonathan M. Irish, Yu Shyr, Ryan J. Sullivan, Igor Puzanov, Jeffrey A. Sosman, Justin M. Balko
Published 2016-01-01

Multisystem Inflammation and Organ Dysfunction After BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccination

by Benjamin Kahn, BA, Sokratis A. Apostolidis, MD, Vatsal Bhatt, MD, Allison R. Greenplate, PhD, Staci Kallish, DO, Anthony LaCava, MD, Alfredo Lucas, BA, Nuala J. Meyer, MD, MS, Dan Negoianu, MD, Alexis R. Ogdie, MD, MSCE, Michael G. S. Shashaty, MD, MSCE, Patricia A. Takach, MD, Leah Zuroff, MD, MS, E. John Wherry, PhD, George L. Anesi, MD, MSCE, MBE
Published 2021-11-01

Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19

by Sokratis A. Apostolidis, Sokratis A. Apostolidis, Amrita Sarkar, Heather M. Giannini, Rishi R. Goel, Divij Mathew, Aae Suzuki, Amy E. Baxter, Amy E. Baxter, Allison R. Greenplate, Allison R. Greenplate, Cécile Alanio, Cécile Alanio, Cécile Alanio, Mohamed Abdel-Hakeem, Mohamed Abdel-Hakeem, Derek A. Oldridge, Derek A. Oldridge, Derek A. Oldridge, Josephine R. Giles, Josephine R. Giles, Josephine R. Giles, Jennifer E. Wu, Jennifer E. Wu, Jennifer E. Wu, Zeyu Chen, Zeyu Chen, Yinghui Jane Huang, Yinghui Jane Huang, Jonathan Belman, Jonathan Belman, Ajinkya Pattekar, Ajinkya Pattekar, Sasikanth Manne, Sasikanth Manne, Oliva Kuthuru, Oliva Kuthuru, Jeanette Dougherty, Jeanette Dougherty, Brittany Weiderhold, Ariel R. Weisman, Caroline A. G. Ittner, Sigrid Gouma, Debora Dunbar, Ian Frank, Alexander C. Huang, Alexander C. Huang, Alexander C. Huang, Laura A. Vella, Laura A. Vella, The UPenn COVID Processing Unit, John P. Reilly, Scott E. Hensley, Scott E. Hensley, Lubica Rauova, Lubica Rauova, Liang Zhao, Nuala J. Meyer, Mortimer Poncz, Mortimer Poncz, Charles S. Abrams, E. John Wherry, E. John Wherry, E. John Wherry, E. John Wherry, Sharon Adamski, Zahidul Alam, Mary M. Addison, Katelyn T. Byrne, Aditi Chandra, Hélène C. Descamps, Nicholas Han, Yaroslav Kaminskiy, Shane C. Kammerman, Justin Kim, Jacob T. Hamilton, Nune Markosyan, Julia Han Noll, Dalia K. Omran, Eric Perkey, Elizabeth M. Prager, Dana Pueschl, Austin Rennels, Jennifer B. Shah, Jake S. Shilan, Nils Wilhausen, Ashley N. Vanderbeck
Published 2022-03-01

Validating a Proteomic Signature of Severe COVID-19

by Christopher V. Cosgriff, MD, MPH, Todd A. Miano, PhD, PharmD, Divij Mathew, PhD, Alexander C. Huang, MD, PhD, Heather M. Giannini, MD, MS, Leticia Kuri-Cervantes, PhD, M. Betina Pampena, PhD, Caroline A. G. Ittner, PhD, Ariel R. Weisman, MS, Roseline S. Agyekum, BS, Thomas G. Dunn, BS, Oluwatosin Oniyide, BS, Alexandra P. Turner, BS, Kurt D’Andrea, BS, Sharon Adamski, BS, Allison R. Greenplate, PhD, Brian J. Anderson, MD, MSCE, Michael O. Harhay, PhD, Tiffanie K. Jones, MD, MPH, MSCE, John P. Reilly, MD, MSCE, Nilam S. Mangalmurti, MD, Michael G. S. Shashaty, MD, MSCE, Michael R. Betts, PhD, E. John Wherry, PhD, Nuala J. Meyer, MD, MS
Published 2022-12-01