Dramatic dysbalancing of the Wnt pathway in breast cancers

by Alexey Koval, Vladimir L. Katanaev
Published 2018-05-01

Clofazimine: A journey of a drug

by Jiabin Xu, Alexey Koval, Vladimir L. Katanaev
Published 2023-11-01

Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells

by Alexey Koval, Xin Zhang, Vladimir L. Katanaev
Published 2023-08-01

Targeting the Wnt signalling pathway in cancer: prospects and perils

by Holly V. Shaw, Alexey Koval, Vladimir L. Katanaev
Published 2019-10-01

Identification of novel elements of the Drosophila blisterome sheds light on potential pathological mechanisms of several human diseases.

by Oleksii Bilousov, Alexey Koval, Amiran Keshelava, Vladimir L Katanaev
Published 2014-01-01

A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers

by Kamal Ahmed, Holly V. Shaw, Alexey Koval, Vladimir L. Katanaev
Published 2016-07-01

Wnt-pathway inhibitors with selective activity against triple-negative breast cancer: From thienopyrimidine to quinazoline inhibitors

by Cédric Boudou, Luce Mattio, Alexey Koval, Valentin Soulard, Vladimir L. Katanaev, Vladimir L. Katanaev
Published 2022-10-01

Wnt-Independent SARS-CoV-2 Infection in Pulmonary Epithelial Cells

by Alexey Koval, Jiabin Xu, Nathalia Williams, Mirco Schmolke, Karl-Heinz Krause, Vladimir L. Katanaev
Published 2023-08-01

Mouse models characterize GNAO1 encephalopathy as a neurodevelopmental disorder leading to motor anomalies: from a severe G203R to a milder C215Y mutation

by Denis Silachev, Alexey Koval, Mikhail Savitsky, Guru Padmasola, Charles Quairiaux, Fabrizio Thorel, Vladimir L. Katanaev
Published 2022-01-01

Beyond TNBC: Repositioning of Clofazimine Against a Broad Range of Wnt-Dependent Cancers

by Jiabin Xu, Jiabin Xu, Alexey Koval, Vladimir L. Katanaev, Vladimir L. Katanaev, Vladimir L. Katanaev
Published 2020-12-01

High capacity in G protein-coupled receptor signaling

by Amiran Keshelava, Gonzalo P. Solis, Micha Hersch, Alexey Koval, Mikhail Kryuchkov, Sven Bergmann, Vladimir L. Katanaev
Published 2018-02-01

Gαi2-induced conductin/axin2 condensates inhibit Wnt/β-catenin signaling and suppress cancer growth

by Cezanne Miete, Gonzalo P. Solis, Alexey Koval, Martina Brückner, Vladimir L. Katanaev, Jürgen Behrens, Dominic B. Bernkopf
Published 2022-02-01

A Cytotoxic Porphyrin from North Pacific Brittle Star <i>Ophiura sarsii</i>

by Antonina Klimenko, Robin Huber, Laurence Marcourt, Estelle Chardonnens, Alexey Koval, Yuri S. Khotimchenko, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Vladimir L. Katanaev
Published 2020-12-01

Cis-regulatory polymorphism at fiz ecdysone oxidase contributes to polygenic evolutionary response to malnutrition in Drosophila.

by Fanny Cavigliasso, Mikhail Savitsky, Alexey Koval, Berra Erkosar, Loriane Savary, Hector Gallart-Ayala, Julijana Ivanisevic, Vladimir L Katanaev, Tadeusz J Kawecki
Published 2024-03-01

Clinical Cases and the Molecular Profiling of a Novel Childhood Encephalopathy-Causing <i>GNAO1</i> Mutation P170R

by Yonika A. Larasati, Gonzalo P. Solis, Alexey Koval, Silja T. Griffiths, Ragnhild Berentsen, Ingvild Aukrust, Gaetan Lesca, Nicolas Chatron, Dorothée Ville, Christian M. Korff, Vladimir L. Katanaev
Published 2023-10-01

Shallow- and Deep-Water <i>Ophiura</i> Species Produce a Panel of Chlorin Compounds with Potent Photodynamic Anticancer Activities

by Antonina Klimenko, Robin Huber, Laurence Marcourt, Dmitry Tabakaev, Alexey Koval, Salim Sh. Dautov, Tatyana N. Dautova, Jean-Luc Wolfender, Rob Thew, Yuri Khotimchenko, Emerson Ferreira Queiroz, Vladimir L. Katanaev
Published 2023-02-01

Integration of Wnt-inhibitory activity and structural novelty scoring results to uncover novel bioactive natural products: new Bicyclo[3.3.1]non-3-ene-2,9-diones from the leaves of...

by Luis-Manuel Quiros-Guerrero, Luis-Manuel Quiros-Guerrero, Laurence Marcourt, Laurence Marcourt, Nathareen Chaiwangrach, Alexey Koval, Emerson Ferreira Queiroz, Emerson Ferreira Queiroz, Bruno David, Antonio Grondin, Vladimir L. Katanaev, Vladimir L. Katanaev, Jean-Luc Wolfender, Jean-Luc Wolfender
Published 2024-04-01

Chemoenzymatic Synthesis of Complex Phenylpropanoid Derivatives by the Botrytis cinerea Secretome and Evaluation of Their Wnt Inhibition Activity

by Robin Huber, Robin Huber, Laurence Marcourt, Laurence Marcourt, Alexey Koval, Sylvain Schnee, Davide Righi, Davide Righi, Emilie Michellod, Vladimir L. Katanaev, Vladimir L. Katanaev, Jean-Luc Wolfender, Jean-Luc Wolfender, Katia Gindro, Emerson Ferreira Queiroz, Emerson Ferreira Queiroz
Published 2022-01-01

Chemoenzymatic Synthesis of Original Stilbene Dimers Possessing Wnt Inhibition Activity in Triple-Negative Breast Cancer Cells Using the Enzymatic Secretome of Botrytis cinerea Per...

by Robin Huber, Robin Huber, Alexey Koval, Laurence Marcourt, Laurence Marcourt, Margaux Héritier, Margaux Héritier, Sylvain Schnee, Emilie Michellod, Leonardo Scapozza, Leonardo Scapozza, Vladimir L. Katanaev, Vladimir L. Katanaev, Jean-Luc Wolfender, Jean-Luc Wolfender, Katia Gindro, Emerson Ferreira Queiroz, Emerson Ferreira Queiroz
Published 2022-04-01

Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells

by Laetitia Seguin, Soline Odouard, Francesca Corlazzoli, Sarah Al Haddad, Laurine Moindrot, Marta Calvo Tardón, Mayra Yebra, Alexey Koval, Eliana Marinari, Viviane Bes, Alexandre Guérin, Mathilde Allard, Sten Ilmjärv, Vladimir L. Katanaev, Paul R. Walker, Karl-Heinz Krause, Valérie Dutoit, Jann N. Sarkaria, Pierre-Yves Dietrich, Érika Cosset
Published 2021-06-01