A mutated factor X activatable by thrombin corrects bleedings in vivo in a rabbit model of antibody-induced hemophilia A

by Toufik Abache, Alexandre Fontayne, Dominique Grenier, Emilie Jacque, Alain Longue, Anne-Sophie Dezetter, Béatrice Souilliart, Guillaume Chevreux, Damien Bataille, Sami Chtourou, Jean-Luc Plantier
Published 2019-11-01

The European AntibotABE Framework Program and Its Update: Development of Innovative Botulinum Antibodies

by Christine Rasetti-Escargueil, Arnaud Avril, Sebastian Miethe, Christelle Mazuet, Yagmur Derman, Katja Selby, Philippe Thullier, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Hannu Korkeala, Dorothea Sesardic, Michael Hust, Michel R. Popoff
Published 2017-10-01

Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B.

by Sebastian Miethe, Christelle Mazuet, Yvonne Liu, Robert Tierney, Christine Rasetti-Escargueil, Arnaud Avril, André Frenzel, Philippe Thullier, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Dorothea Sesardic, Michael Hust, Michel Robert Popoff
Published 2016-01-01

In Vivo Human Single‐Chain Fragment Variable Phage Display‐Assisted Identification of Galectin‐3 as a New Biomarker of Atherosclerosis

by Audrey Hemadou, Alexandre Fontayne, Jeanny Laroche‐Traineau, Florence Ottones, Philippe Mondon, Stéphane Claverol, Éric Ducasse, Stéphane Sanchez, Sarah Mohamad, Cyril Lorenzato, Martine Duonor‐Cerutti, Gisèle Clofent‐Sanchez, Marie‐Josée Jacobin‐Valat
Published 2021-10-01

Neutralization of Botulinum Neurotoxin Type E by a Humanized Antibody

by Yağmur Derman, Katja Selby, Sebastian Miethe, André Frenzel, Yvonne Liu, Christine Rasetti-Escargueil, Arnaud Avril, Thibaut Pelat, Remi Urbain, Alexandre Fontayne, Philippe Thullier, Dorothea Sesardic, Miia Lindström, Michael Hust, Hannu Korkeala
Published 2016-09-01

The Dual Targeting of FcRn and FcγRs via Monomeric Fc Fragments Results in Strong Inhibition of IgG-Dependent Autoimmune Pathologies

by Céline Monnet, Emilie Jacque, Christophe de Romeuf, Alexandre Fontayne, Toufik Abache, Nathalie Fournier, Gilles Dupont, Delphine Derache, Anais Engrand, Aurélie Bauduin, Aurélie Terrier, Alexander Seifert, Cécile Beghin, Alain Longue, Nicholas Masiello, Laetitia Danino, Michel Nogre, Anais Raia, Frederic Dhainaut, Louis Fauconnier, Dieudonnée Togbe, Carmen Reitinger, Falk Nimmerjahn, Wil Stevens, Sami Chtourou, Philippe Mondon
Published 2021-08-01