Inhibition of Serine Proteases as a Novel Therapeutic Strategy for Abdominal Pain in IBS

by Lisse Decraecker, Guy Boeckxstaens, Alexandre Denadai-Souza
Published 2022-05-01

Tumor necrosis factor receptor-associated factor 6 interaction with alpha-synuclein enhances cell death through the Nuclear Factor-kB pathway

by Lidia M. Yshii, Adriana O. Manfiolli, Alexandre Denadai-Souza, Paula F. Kinoshita, Marcelo D. Gomes, Cristoforo Scavone
Published 2020-12-01

Effect of tryptase inhibition on joint inflammation: a pharmacological and lentivirus-mediated gene transfer study

by Alexandre Denadai-Souza, Camilla Moreira Ribeiro, Corinne Rolland, Anne Thouard, Céline Deraison, Cristoforo Scavone, Daniel Gonzalez-Dunia, Nathalie Vergnolle, Maria Christina Werneck Avellar
Published 2017-06-01

Sexual dimorphism in PAR2-dependent regulation of primitive colonic cells

by Julie Noguerol, Pierre-Jean Roustan, Mikael N’Taye, Léo Delcombel, Corinne Rolland, Laura Guiraud, David Sagnat, Anissa Edir, Chrystelle Bonnart, Alexandre Denadai-Souza, Céline Deraison, Nathalie Vergnolle, Claire Racaud-Sultan
Published 2019-09-01

Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples

by Reza Mirzazadeh, Zaneta Andrusivova, Ludvig Larsson, Phillip T. Newton, Leire Alonso Galicia, Xesús M. Abalo, Mahtab Avijgan, Linda Kvastad, Alexandre Denadai-Souza, Nathalie Stakenborg, Alexandra B. Firsova, Alia Shamikh, Aleksandra Jurek, Niklas Schultz, Monica Nistér, Christos Samakovlis, Guy Boeckxstaens, Joakim Lundeberg
Published 2023-01-01

Chemically diverse activity-based probes with unexpected inhibitory mechanisms targeting trypsin-like serine proteases

by Alba Ramos-Llorca, Lisse Decraecker, Valérie M. Y. Cacheux, Irena Zeiburlina, Michelle De bruyn, Louise Battut, Carlos Moreno-Cinos, Davide Ceradini, Eric Espinosa, Gilles Dietrich, Maya Berg, Ingrid De Meester, Pieter Van Der Veken, Guy Boeckxstaens, Anne-Marie Lambeir, Alexandre Denadai-Souza, Koen Augustyns
Published 2023-01-01

Active thrombin produced by the intestinal epithelium controls mucosal biofilms

by Jean-Paul Motta, Alexandre Denadai-Souza, David Sagnat, Laura Guiraud, Anissa Edir, Chrystelle Bonnart, Mireille Sebbag, Perrine Rousset, Ariane Lapeyre, Carine Seguy, Noa Mathurine-Thomas, Heather J. Galipeau, Delphine Bonnet, Laurent Alric, Andre G. Buret, John L. Wallace, Antoine Dufour, Elena F. Verdu, Morley D. Hollenberg, Eric Oswald, Matteo Serino, Celine Deraison, Nathalie Vergnolle
Published 2019-07-01