Phase 1 Trial With the Cell-Based Immune Primer Ilixadencel, Alone, and Combined With Sorafenib, in Advanced Hepatocellular Carcinoma

by Magnus Rizell, Magnus Rizell, Malin Sternby Eilard, Malin Sternby Eilard, Mats Andersson, Mats Andersson, Bengt Andersson, Alex Karlsson-Parra, Alex Karlsson-Parra, Peter Suenaert
Published 2019-01-01

P1383: STRONG AND SELECTIVE EX VIVO EXPANSION OF ADAPTIVE NKG2C+/CD57+ NK CELLS FROM CMV SEROPOSITIVE DONORS USING DENDRITIC CELLS DERIVED FROM THE LEUKEMIC CELL LINE DCONE AS FEED...

by Haoxiao Zuo, Hester van Zeeburg, Alex Karlsson-Parra, Satwinder Kaur Singh
Published 2023-08-01

Characterization of Innate Immunity in an Extended Whole Blood Model of Human Islet Allotransplantation

by Maria Hårdstedt, Susanne Lindblom, Alex Karlsson-Parra, Bo Nilsson, Olle Korsgren
Published 2016-03-01

Allogeneic lymphocyte-licensed DCs expand T cells with improved antitumor activity and resistance to oxidative stress and immunosuppressive factors

by Chuan Jin, Di Yu, Victoria Hillerdal, AnnaCarin Wallgren, Alex Karlsson-Parra, Magnus Essand
Published 2014-01-01

Pro-inflammatory allogeneic DCs promote activation of bystander immune cells and thereby license antigen-specific T-cell responses

by Grammatiki Fotaki, Chuan Jin, Mohanraj Ramachandran, Iliana Kyriaki Kerzeli, Alex Karlsson-Parra, Di Yu, Magnus Essand
Published 2018-03-01

Proinflammatory allogeneic dendritic cells enhance the therapeutic efficacy of systemic anti-4-1BB treatment

by Arwa Ali, Menghan Gao, Alexandros Iskantar, Hai Wang, Hai Wang, Alex Karlsson-Parra, Di Yu, Chuan Jin
Published 2023-08-01

Intratumoral administration of pro-inflammatory allogeneic dendritic cells improved the anti-tumor response of systemic anti-CTLA-4 treatment via unleashing a T cell-dependent resp...

by Chuan Jin, Arwa Ali, Alexandros Iskantar, Grammatiki Fotaki, Hai Wang, Magnus Essand, Alex Karlsson-Parra, Di Yu
Published 2022-12-01

Cancer vaccine based on a combination of an infection-enhanced adenoviral vector and pro-inflammatory allogeneic DCs leads to sustained antigen-specific immune responses in three m...

by Grammatiki Fotaki, Chuan Jin, Iliana Kyriaki Kerzeli, Mohanraj Ramachandran, Minttu-Maria Martikainen, Alex Karlsson-Parra, Di Yu, Magnus Essand
Published 2018-03-01

Intratumorally injected pro-inflammatory allogeneic dendritic cells as immune enhancers: a first-in-human study in unfavourable risk patients with metastatic renal cell carcinoma

by Anna Laurell, Maria Lönnemark, Einar Brekkan, Anders Magnusson, Anna Tolf, Anna Carin Wallgren, Bengt Andersson, Lars Adamson, Rolf Kiessling, Alex Karlsson-Parra
Published 2017-06-01

Transfer of Cellular Content from the Allogeneic Cell-Based Cancer Vaccine DCP-001 to Host Dendritic Cells Hinges on Phosphatidylserine and Is Enhanced by CD47 Blockade

by Haoxiao Zuo, Marie-José C. van Lierop, Jorn Kaspers, Remco Bos, Anneke Reurs, Saheli Sarkar, Tania Konry, Alwin Kamermans, Gijs Kooij, Helga E. de Vries, Tanja D. de Gruijl, Alex Karlsson-Parra, Erik H. Manting, Ada M. Kruisbeek, Satwinder Kaur Singh
Published 2021-11-01

Ilixadencel, a Cell-based Immune Primer, plus Sunitinib Versus Sunitinib Alone in Metastatic Renal Cell Carcinoma: A Randomized Phase 2 Study

by Magnus Lindskog, Anna Laurell, Anders Kjellman, Bohuslav Melichar, Pablo Maroto Rey, Henryk Zieliński, Felipe Villacampa, Pierre Bigot, Bajory Zoltan, Omi Parikh, David Vazquez Alba, Åsa Jellvert, Tibor Flaskó, Enrique Gallardo, Maria José Ribal Caparrós, Gunta Purkalne, Peter Suenaert, Alex Karlsson-Parra, Börje Ljungberg
Published 2022-06-01