Learning the Regulatory Code of Gene Expression

by Jan Zrimec, Filip Buric, Mariia Kokina, Mariia Kokina, Victor Garcia, Aleksej Zelezniak, Aleksej Zelezniak
Published 2021-06-01

Contribution of network connectivity in determining the relationship between gene expression and metabolite concentration changes.

by Aleksej Zelezniak, Steven Sheridan, Kiran Raosaheb Patil
Published 2014-04-01

Plastic-Degrading Potential across the Global Microbiome Correlates with Recent Pollution Trends

by Jan Zrimec, Mariia Kokina, Sara Jonasson, Francisco Zorrilla, Aleksej Zelezniak
Published 2021-10-01

Metabolic network topology reveals transcriptional regulatory signatures of type 2 diabetes.

by Aleksej Zelezniak, Tune H Pers, Simão Soares, Mary Elizabeth Patti, Kiran Raosaheb Patil
Published 2010-04-01

Bayesian genome scale modelling identifies thermal determinants of yeast metabolism

by Gang Li, Yating Hu, Jan Zrimec, Hao Luo, Hao Wang, Aleksej Zelezniak, Boyang Ji, Jens Nielsen
Published 2021-01-01

Performance of Regression Models as a Function of Experiment Noise

by Gang Li, Jan Zrimec, Boyang Ji, Jun Geng, Johan Larsbrink, Aleksej Zelezniak, Jens Nielsen, Martin KM Engqvist
Published 2021-06-01

The self-inhibitory nature of metabolic networks and its alleviation through compartmentalization

by Mohammad Tauqeer Alam, Viridiana Olin-Sandoval, Anna Stincone, Markus A. Keller, Aleksej Zelezniak, Ben F. Luisi, Markus Ralser
Published 2017-07-01

Deep learning suggests that gene expression is encoded in all parts of a co-evolving interacting gene regulatory structure

by Jan Zrimec, Christoph S. Börlin, Filip Buric, Azam Sheikh Muhammad, Rhongzen Chen, Verena Siewers, Vilhelm Verendel, Jens Nielsen, Mats Töpel, Aleksej Zelezniak
Published 2020-12-01

Controlling gene expression with deep generative design of regulatory DNA

by Jan Zrimec, Xiaozhi Fu, Azam Sheikh Muhammad, Christos Skrekas, Vykintas Jauniskis, Nora K. Speicher, Christoph S. Börlin, Vilhelm Verendel, Morteza Haghir Chehreghani, Devdatt Dubhashi, Verena Siewers, Florian David, Jens Nielsen, Aleksej Zelezniak
Published 2022-08-01

Enhanced metabolism and negative regulation of ER stress support higher erythropoietin production in HEK293 cells

by Rasool Saghaleyni, Magdalena Malm, Noah Moruzzi, Jan Zrimec, Ronia Razavi, Num Wistbacka, Hannes Thorell, Anton Pintar, Andreas Hober, Fredrik Edfors, Veronique Chotteau, Per-Olof Berggren, Luigi Grassi, Aleksej Zelezniak, Thomas Svensson, Diane Hatton, Jens Nielsen, Jonathan L. Robinson, Johan Rockberg
Published 2022-06-01

A proteomic survival predictor for COVID-19 patients in intensive care

by Vadim Demichev, Pinkus Tober-Lau, Tatiana Nazarenko, Oliver Lemke, Simran Kaur Aulakh, Harry J. Whitwell, Annika Röhl, Anja Freiwald, Mirja Mittermaier, Lukasz Szyrwiel, Daniela Ludwig, Clara Correia-Melo, Lena J. Lippert, Elisa T. Helbig, Paula Stubbemann, Nadine Olk, Charlotte Thibeault, Nana-Maria Grüning, Oleg Blyuss, Spyros Vernardis, Matthew White, Christoph B. Messner, Michael Joannidis, Thomas Sonnweber, Sebastian J. Klein, Alex Pizzini, Yvonne Wohlfarter, Sabina Sahanic, Richard Hilbe, Benedikt Schaefer, Sonja Wagner, Felix Machleidt, Carmen Garcia, Christoph Ruwwe-Glösenkamp, Tilman Lingscheid, Laure Bosquillon de Jarcy, Miriam S. Stegemann, Moritz Pfeiffer, Linda Jürgens, Sophy Denker, Daniel Zickler, Claudia Spies, Andreas Edel, Nils B. Müller, Philipp Enghard, Aleksej Zelezniak, Rosa Bellmann-Weiler, Günter Weiss, Archie Campbell, Caroline Hayward, David J. Porteous, Riccardo E. Marioni, Alexander Uhrig, Heinz Zoller, Judith Löffler-Ragg, Markus A. Keller, Ivan Tancevski, John F. Timms, Alexey Zaikin, Stefan Hippenstiel, Michael Ramharter, Holger Müller-Redetzky, Martin Witzenrath, Norbert Suttorp, Kathryn Lilley, Michael Mülleder, Leif Erik Sander, Florian Kurth, Markus Ralser
Published 2022-01-01

A proteomic survival predictor for COVID-19 patients in intensive care.

by Vadim Demichev, Pinkus Tober-Lau, Tatiana Nazarenko, Oliver Lemke, Simran Kaur Aulakh, Harry J Whitwell, Annika Röhl, Anja Freiwald, Mirja Mittermaier, Lukasz Szyrwiel, Daniela Ludwig, Clara Correia-Melo, Lena J Lippert, Elisa T Helbig, Paula Stubbemann, Nadine Olk, Charlotte Thibeault, Nana-Maria Grüning, Oleg Blyuss, Spyros Vernardis, Matthew White, Christoph B Messner, Michael Joannidis, Thomas Sonnweber, Sebastian J Klein, Alex Pizzini, Yvonne Wohlfarter, Sabina Sahanic, Richard Hilbe, Benedikt Schaefer, Sonja Wagner, Felix Machleidt, Carmen Garcia, Christoph Ruwwe-Glösenkamp, Tilman Lingscheid, Laure Bosquillon de Jarcy, Miriam S Stegemann, Moritz Pfeiffer, Linda Jürgens, Sophy Denker, Daniel Zickler, Claudia Spies, Andreas Edel, Nils B Müller, Philipp Enghard, Aleksej Zelezniak, Rosa Bellmann-Weiler, Günter Weiss, Archie Campbell, Caroline Hayward, David J Porteous, Riccardo E Marioni, Alexander Uhrig, Heinz Zoller, Judith Löffler-Ragg, Markus A Keller, Ivan Tancevski, John F Timms, Alexey Zaikin, Stefan Hippenstiel, Michael Ramharter, Holger Müller-Redetzky, Martin Witzenrath, Norbert Suttorp, Kathryn Lilley, Michael Mülleder, Leif Erik Sander, PA-COVID-19 Study group, Florian Kurth, Markus Ralser
Published 2022-01-01