Development of Pharmacological Strategies with Therapeutic Potential in Ischemic Stroke

by Alejandro Escobar-Peso, Emma Martínez-Alonso, Jaime Masjuan, Alberto Alcázar
Published 2023-12-01

Improving the Efficacy of Quinolylnitrones for Ischemic Stroke Therapy, QN4 and QN15 as New Neuroprotective Agents after Oxygen–Glucose Deprivation/Reoxygenation-Induced Neuronal I...

by José M. Alonso, Alejandro Escobar-Peso, Israel Fernández, Alberto Alcázar, José Marco-Contelles
Published 2022-11-01

Differential Association of 4E-BP2-Interacting Proteins Is Related to Selective Delayed Neuronal Death after Ischemia

by Emma Martínez-Alonso, Natalia Guerra-Pérez, Alejandro Escobar-Peso, Ignacio Regidor, Jaime Masjuan, Alberto Alcázar
Published 2021-09-01

Dihydropyrimidinase-Related Protein 2 Is a New Partner in the Binding between 4E-BP2 and eIF4E Related to Neuronal Death after Cerebral Ischemia

by Emma Martínez-Alonso, Alejandro Escobar-Peso, Natalia Guerra-Pérez, Marcel Roca, Jaime Masjuan, Alberto Alcázar
Published 2023-05-01

Phosphorylation of Eukaryotic Initiation Factor 4G1 (eIF4G1) at Ser1147 Is Specific for eIF4G1 Bound to eIF4E in Delayed Neuronal Death after Ischemia

by Emma Martínez-Alonso, Natalia Guerra-Pérez, Alejandro Escobar-Peso, Lorena Peracho, Rocío Vera-Lechuga, Antonio Cruz-Culebras, Jaime Masjuan, Alberto Alcázar
Published 2022-02-01

Characterization of a CholesteroNitrone (ISQ-201), a Novel Drug Candidate for the Treatment of Ischemic Stroke

by Emma Martínez-Alonso, Alejandro Escobar-Peso, Maria I. Ayuso, Rafael Gonzalo-Gobernado, Mourad Chioua, Juan J. Montoya, Joan Montaner, Israel Fernández, José Marco-Contelles, Alberto Alcázar
Published 2020-03-01

Privileged Quinolylnitrones for the Combined Therapy of Ischemic Stroke and Alzheimer’s Disease

by José M. Alonso, Alejandro Escobar-Peso, Alejandra Palomino-Antolín, Daniel Diez-Iriepa, Mourad Chioua, Emma Martínez-Alonso, Isabel Iriepa, Javier Egea, Alberto Alcázar, José Marco-Contelles
Published 2021-08-01

Preclinical Characterization of Antioxidant Quinolyl Nitrone QN23 as a New Candidate for the Treatment of Ischemic Stroke

by Emma Martínez-Alonso, Alejandro Escobar-Peso, Alicia Aliena-Valero, Germán Torregrosa, Mourad Chioua, Rocío Fernández-Serra, Daniel González-Nieto, Youness Ouahid, Juan B. Salom, Jaime Masjuan, José Marco-Contelles, Alberto Alcázar
Published 2022-06-01