Bio-Mimicking, Electrical Excitability Phenomena Associated With Synthetic Macromolecular Systems: A Brief Review With Connections to the Cytoskeleton and Membraneless Organelles

by Gary E. Wnek, Alberto C. S. Costa, Alberto C. S. Costa, Susan K. Kozawa
Published 2022-03-01

Evidence of Energy Metabolism Alterations in Cultured Neonatal Astrocytes Derived from the Ts65Dn Mouse Model of Down Syndrome

by Bruna L. Zampieri, Alberto C. S. Costa
Published 2022-01-01

Protein dynamics associated with failed and rescued learning in the Ts65Dn mouse model of Down syndrome.

by Md Mahiuddin Ahmed, A Ranjitha Dhanasekaran, Aaron Block, Suhong Tong, Alberto C S Costa, Melissa Stasko, Katheleen J Gardiner
Published 2015-01-01

Pharmacological Modulation of Three Modalities of CA1 Hippocampal Long-Term Potentiation in the Ts65Dn Mouse Model of Down Syndrome

by Jonah J. Scott-McKean, Adriano L. Roque, Krystyna Surewicz, Mark W. Johnson, Witold K. Surewicz, Alberto C. S. Costa
Published 2018-01-01

On the Design of Broad-Based Neuropsychological Test Batteries to Assess the Cognitive Abilities of Individuals with Down Syndrome in the Context of Clinical Trials

by Ines A. Basten, Richard Boada, Hudson G. Taylor, Katherine Koenig, Veridiana L. Barrionuevo, Ana C. Brandão, Alberto C. S. Costa
Published 2018-11-01

Microcapillary Reactors via Coaxial Electrospinning: Fabrication of Small Poly(Acrylic Acid) Gel Beads and Thin Threads of Biological Cell Dimensions

by Susan K. Kozawa, Audrey Lord, Jonah J. Scott-McKean, Anne Y. Walker, Alberto C. S. Costa, Gary E. Wnek
Published 2021-03-01

Novel DYRK1A Inhibitor Rescues Learning and Memory Deficits in a Mouse Model of Down Syndrome

by Wenche Stensen, Ulli Rothweiler, Richard Alan Engh, Melissa R. Stasko, Ilya Bederman, Alberto C. S. Costa, Anders Fugelli, John S. Mjøen Svendsen
Published 2021-11-01

Noninvasive assessment of autonomic modulation of heart rate variability in the Ts65Dn mouse model of Down syndrome: A proof of principle study

by Adriano L. Roque, Mark W. Johnson, Melissa R. Stasko, Luiz C. deAbreu, Talita D. daSilva, Alberto C.S. Costa
Published 2020-06-01

Emergence of Treadmill Running Ability and Quantitative Assessment of Gait Dynamics in Young Ts65Dn Mice: A Mouse Model for Down Syndrome

by Jonah J. Scott-McKean, Ryan Jones, Mark W. Johnson, Joyce Mier, Ines A. Basten, Melissa R. Stasko, Alberto C. S. Costa
Published 2023-04-01

Soluble prion protein and its N-terminal fragment prevent impairment of synaptic plasticity by Aβ oligomers: Implications for novel therapeutic strategy in Alzheimer's disease

by Jonah J. Scott-McKean, Krystyna Surewicz, Jin-Kyu Choi, Vernon A. Ruffin, Ahlam I. Salameh, Krzysztof Nieznanski, Alberto C.S. Costa, Witold K. Surewicz
Published 2016-07-01

Atypical electrophysiological and behavioral responses to diazepam in a leading mouse model of Down syndrome

by Daniella B. Victorino, Daniel J. L. L. Pinheiro, Jonah J. Scott-McKean, Sarah Barker, Melissa R. Stasko, Jean Faber, Carla A. Scorza, Alberto C. S. Costa
Published 2021-05-01

COVID-19 in Children with Down Syndrome: Data from the Trisomy 21 Research Society Survey

by David Emes, Anke Hüls, Nicole Baumer, Mara Dierssen, Shiela Puri, Lauren Russell, Stephanie L. Sherman, Andre Strydom, Stefania Bargagna, Ana Cláudia Brandão, Alberto C. S. Costa, Patrick T. Feany, Brian Allen Chicoine, Sujay Ghosh, Anne-Sophie Rebillat, Giuseppina Sgandurra, Diletta Valentini, Tilman R. Rohrer, Johannes Levin, Monica Lakhanpaul, on behalf of the Trisomy 21 Research Society COVID-19 Initiative Study Group
Published 2021-10-01

Medical vulnerability of individuals with Down syndrome to severe COVID-19–data from the Trisomy 21 Research Society and the UK ISARIC4C survey

by Anke Hüls, Alberto C.S. Costa, Mara Dierssen, R. Asaad Baksh, Stefania Bargagna, Nicole T. Baumer, Ana Claudia Brandão, Angelo Carfi, Maria Carmona-Iragui, Brian Allen Chicoine, Sujay Ghosh, Monica Lakhanpaul, Coral Manso, Miguel-Angel Mayer, Maria del Carmen Ortega, Diego Real de Asua, Anne-Sophie Rebillat, Lauren Ashley Russell, Giuseppina Sgandurra, Diletta Valentini, Stephanie L. Sherman, Andre Strydom
Published 2021-03-01

COVID-19 Vaccination of Individuals with Down Syndrome—Data from the Trisomy 21 Research Society Survey on Safety, Efficacy, and Factors Associated with the Decision to Be Vaccinat...

by Anke Hüls, Patrick T. Feany, Sophia Isabella Zisman, Alberto C. S. Costa, Mara Dierssen, Robert Balogh, Stefania Bargagna, Nicole T. Baumer, Ana Claudia Brandão, Angelo Carfi, Brian Allen Chicoine, Sujay Ghosh, Monica Lakhanpaul, Johannes Levin, Yona Lunsky, Coral Manso, Eitan Okun, Diego Real de Asua, Anne-Sophie Rebillat, Tilman R. Rohrer, Giuseppina Sgandurra, Diletta Valentini, Stephanie L. Sherman, Andre Strydom, on behalf of the Trisomy 21 Research Society COVID-19 Initiative
Published 2022-03-01

Cross-Sectional Exploration of Plasma Biomarkers of Alzheimer’s Disease in Down Syndrome: Early Data from the Longitudinal Investigation for Enhancing Down Syndrome Research (LIFE-...

by James A. Hendrix, David C. Airey, Angela Britton, Anna D. Burke, George T. Capone, Ronelyn Chavez, Jacqueline Chen, Brian Chicoine, Alberto C. S. Costa, Jeffrey L. Dage, Eric Doran, Anna Esbensen, Casey L. Evans, Kelley M. Faber, Tatiana M. Foroud, Sarah Hart, Kelsey Haugen, Elizabeth Head, Suzanne Hendrix, Hampus Hillerstrom, Priya S. Kishnani, Kavita Krell, Duvia Lara Ledesma, Florence Lai, Ira Lott, Cesar Ochoa-Lubinoff, Jennifer Mason, Jessie Nicodemus-Johnson, Nicholas Kyle Proctor, Margaret B. Pulsifer, Carolyn Revta, H. Diana Rosas, Tracie C. Rosser, Stephanie Santoro, Kim Schafer, Thomas Scheidemantel, Frederick Schmitt, Brian G. Skotko, Melissa R. Stasko, Amy Talboy, Amy Torres, Kristi Wilmes, Jason Woodward, Jennifer A. Zimmer, Howard H. Feldman, William Mobley
Published 2021-04-01