Article Commentary: Should We Consider Cancers as Embryonic Diseases or as Consequences of Stem-Cell Deregulation?

by Jérémy Bastid, Alain Puisieux, Stéphane Ansieau
Published 2008-01-01

The cell-of-origin dictates the genomic landscape of breast cancers

by Alain Puisieux, Roxane M. Pommier, Agnès Tissier, Anne-Pierre Morel
Published 2017-07-01

Quantifying local malignant adaptation in tissue‐specific evolutionary trajectories by harnessing cancer’s repeatability at the genetic level

by Natsuki Tokutomi, Caroline Moyret‐Lalle, Alain Puisieux, Sumio Sugano, Pierre Martinez
Published 2019-06-01

Cellular Plasticity: A Route to Senescence Exit and Tumorigenesis

by Hadrien De Blander, Anne-Pierre Morel, Aruni P. Senaratne, Maria Ouzounova, Alain Puisieux
Published 2021-09-01

Generation of breast cancer stem cells through epithelial-mesenchymal transition.

by Anne-Pierre Morel, Marjory Lièvre, Clémence Thomas, George Hinkal, Stéphane Ansieau, Alain Puisieux
Published 2008-01-01

Assessing Cell Activities rather than Identities to Interpret Intra-Tumor Phenotypic Diversity and Its Dynamics

by Laloé Monteiro, Lydie Da Silva, Boris Lipinski, Frédérique Fauvet, Arnaud Vigneron, Alain Puisieux, Pierre Martinez
Published 2020-05-01

Snail family members unequally trigger EMT and thereby differ in their ability to promote the neoplastic transformation of mammary epithelial cells.

by Baptiste Gras, Laurent Jacqueroud, Anne Wierinckx, Christelle Lamblot, Frédérique Fauvet, Joël Lachuer, Alain Puisieux, Stéphane Ansieau
Published 2014-01-01

Modulation of oxidative stress by twist oncoproteins.

by Nicolas Floc'h, Jakub Kolodziejski, Leila Akkari, Yannick Simonin, Stéphane Ansieau, Alain Puisieux, Urszula Hibner, Patrice Lassus
Published 2013-01-01

Intestinal Epithelial Cells Adapt to Chronic Inflammation through Partial Genetic Reprogramming

by Guillaume Collin, Jean-Philippe Foy, Nicolas Aznar, Nicolas Rama, Anne Wierinckx, Pierre Saintigny, Alain Puisieux, Stéphane Ansieau
Published 2023-02-01

Opposite Roles for ZEB1 and TMEJ in the Regulation of Breast Cancer Genome Stability

by Mélanie K. Prodhomme, Mélanie K. Prodhomme, Sarah Péricart, Roxane M. Pommier, Anne-Pierre Morel, Anne-Pierre Morel, Anne-Cécile Brunac, Camille Franchet, Caroline Moyret-Lalle, Caroline Moyret-Lalle, Pierre Brousset, Alain Puisieux, Alain Puisieux, Jean-Sébastien Hoffmann, Agnès Tissier, Agnès Tissier
Published 2021-08-01

The Heterodimeric TWIST1-E12 Complex Drives the Oncogenic Potential of TWIST1 in Human Mammary Epithelial Cells

by Laurent Jacqueroud, Charlotte Bouard, Geoffrey Richard, Léa Payen, Mojgan Devouassoux-Shisheboran, Douglas B. Spicer, Julie Caramel, Guillaume Collin, Alain Puisieux, Agnès Tissier, Stéphane Ansieau
Published 2016-05-01

Integrated analysis highlights APC11 protein expression as a likely new independent predictive marker for colorectal cancer

by Youenn Drouet, Isabelle Treilleux, Alain Viari, Sophie Léon, Mojgan Devouassoux-Shisheboran, Nicolas Voirin, Christelle de la Fouchardière, Brigitte Manship, Alain Puisieux, Christine Lasset, Caroline Moyret-Lalle
Published 2018-05-01

Comprehensive characterization of claudin-low breast tumors reflects the impact of the cell-of-origin on cancer evolution

by Roxane M. Pommier, Amélien Sanlaville, Laurie Tonon, Janice Kielbassa, Emilie Thomas, Anthony Ferrari, Anne-Sophie Sertier, Frédéric Hollande, Pierre Martinez, Agnès Tissier, Anne-Pierre Morel, Maria Ouzounova, Alain Puisieux
Published 2020-07-01

A 13-gene expression-based radioresistance score highlights the heterogeneity in the response to radiation therapy across HPV-negative HNSCC molecular subtypes

by Jean-Philippe Foy, Louis Bazire, Sandra Ortiz-Cuaran, Sophie Deneuve, Janice Kielbassa, Emilie Thomas, Alain Viari, Alain Puisieux, Patrick Goudot, Chloé Bertolus, Nicolas Foray, Youlia Kirova, Pierre Verrelle, Pierre Saintigny
Published 2017-09-01

TWIST1 a new determinant of epithelial to mesenchymal transition in EGFR mutated lung adenocarcinoma.

by Karine Pallier, Anatole Cessot, Jean-Francois Côté, Pierre-Alexandre Just, Aurélie Cazes, Elizabeth Fabre, Claire Danel, Marc Riquet, Mojgan Devouassoux-Shisheboran, Stéphane Ansieau, Alain Puisieux, Pierre Laurent-Puig, Hélène Blons
Published 2012-01-01

EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.

by Anne-Pierre Morel, George W Hinkal, Clémence Thomas, Frédérique Fauvet, Stéphanie Courtois-Cox, Anne Wierinckx, Mojgan Devouassoux-Shisheboran, Isabelle Treilleux, Agnès Tissier, Baptiste Gras, Julie Pourchet, Isabelle Puisieux, Gareth J Browne, Douglas B Spicer, Joël Lachuer, Stéphane Ansieau, Alain Puisieux
Published 2012-01-01

ZEB1 transcription factor promotes immune escape in melanoma

by Christophe Caux, Stephane Dalle, Arnaud de la Fouchardière, Laurie Tonon, Maud Plaschka, Valentin Benboubker, Maxime Grimont, Justine Berthet, Jonathan Lopez, Myrtille Le-Bouar, Brigitte Balme, Garance Tondeur, Lionel Larue, Alain Puisieux, Yenkel Grinberg-Bleyer, Nathalie Bendriss-Vermare, Bertrand Dubois, Julie Caramel
Published 2022-03-01

Immunological and classical subtypes of oral premalignant lesions

by Jean-Philippe Foy, Chloé Bertolus, Sandra Ortiz-Cuaran, Marie-Alexandra Albaret, William N Williams, Wenhua Lang, Solène Destandau, Geneviève De Souza, Emilie Sohier, Janice Kielbassa, Emilie Thomas, Sophie Deneuve, Patrick Goudot, Alain Puisieux, Alain Viari, Li Mao, Christophe Caux, SM Lippman, P Saintigny
Published 2018-12-01

CDYL2 Epigenetically Regulates MIR124 to Control NF-κB/STAT3-Dependent Breast Cancer Cell Plasticity

by Maha Siouda, Audrey D. Dujardin, Laetitia Barbollat-Boutrand, Marco A. Mendoza-Parra, Benjamin Gibert, Maria Ouzounova, Jebrane Bouaoud, Laurie Tonon, Marie Robert, Jean-Philippe Foy, Vincent Lavergne, Serge N. Manie, Alain Viari, Alain Puisieux, Gabriel Ichim, Hinrich Gronemeyer, Pierre Saintigny, Peter Mulligan
Published 2020-06-01

Correction: Inactivation of TIF1γ Cooperates with Kras to Induce Cystic Tumors of the Pancreas.

by David F. Vincent, Kai-Ping Yan, Isabelle Treilleux, Fabien Gay, Vanessa Arfi, Bastien Kaniewski, Julien C. Marie, Florian Lepinasse, Sylvie Martel, Sophie Goddard-Leon, Juan L. Iovanna, Pierre Dubus, Stéphane Garcia, Alain Puisieux, Ruth Rimokh, Nabeel Bardeesy, Jean-Yves Scoazec, Régine Losson, Laurent Bartholin
Published 2009-08-01