A G-protein-biased S1P1 agonist, SAR247799, improved LVH and diastolic function in a rat model of metabolic syndrome

by Maria Francesca Evaristi, Bruno Poirier, Xavier Chénedé, Anne-Marie Lefebvre, Alain Roccon, Florence Gillot, Sandra Beeské, Alain Corbier, Marie-Pierre Pruniaux-Harnist, Philip Janiak, Ashfaq A. Parkar
Published 2022-01-01

A G-protein-biased S1P1 agonist, SAR247799, improved LVH and diastolic function in a rat model of metabolic syndrome.

by Maria Francesca Evaristi, Bruno Poirier, Xavier Chénedé, Anne-Marie Lefebvre, Alain Roccon, Florence Gillot, Sandra Beeské, Alain Corbier, Marie-Pierre Pruniaux-Harnist, Philip Janiak, Ashfaq A Parkar
Published 2022-01-01

Characterization of a new potent and long-lasting single chain peptide agonist of RXFP1 in cells and in vivo translational models

by Stephane Illiano, Bruno Poirier, Claire Minoletti, Olivier Pasquier, Laurence Riva, Xavier Chenede, Isabelle Menguy, Michel Guillotel, Philippe Prigent, Stéphane Le Claire, Florence Gillot, Gilbert Thill, François Lo Presti, Alain Corbier, Jean-Christophe Le Bail, Patrick Grailhe, Edith Monteagudo, Raffaele Ingenito, Elisabetta Bianchi, Christophe Philippo, Olivier Duclos, Sergio Mallart, Ross Bathgate, Philip Janiak
Published 2022-11-01