24S-Hydroxycholesterol Correlates With Tau and Is Increased in Cerebrospinal Fluid in Parkinson's Disease and Corticobasal Syndrome

by Ingemar Björkhem, Kalicharan Patra, Adam L. Boxer, Per Svenningsson
Published 2018-09-01

Tau pathology in neurodegenerative disease: disease mechanisms and therapeutic avenues

by Niyatee Samudra, Courtney Lane-Donovan, Lawren VandeVrede, Adam L. Boxer
Published 2023-06-01

Associations Between Amantadine Usage, Gait, and Cognition in PSP: A post-hoc Analysis of the Davunetide Trial

by Marian L. Dale, Barbara H. Brumbach, Adam L. Boxer, Amie L. Hiller
Published 2020-12-01

Longitudinal white matter change in frontotemporal dementia subtypes and sporadic late onset Alzheimer's disease

by Fanny M. Elahi, Gabe Marx, Yann Cobigo, Adam M. Staffaroni, John Kornak, Duygu Tosun, Adam L. Boxer, Joel H. Kramer, Bruce L. Miller, Howard J. Rosen
Published 2017-01-01

Symptomatic amyloid‐related imaging abnormalities in an APOE ε4/ε4 patient treated with aducanumab

by Lawren VandeVrede, Daniel M Gibbs, Mary Koestler, Renaud La Joie, Peter A. Ljubenkov, Karine Provost, David Soleimani‐Meigooni, Amelia Strom, Elena Tsoy, Gil D. Rabinovici, Adam L. Boxer
Published 2020-01-01

Advancing functional dysconnectivity and atrophy in progressive supranuclear palsy

by Jesse A. Brown, Alice Y. Hua, Andrew Trujillo, Suneth Attygalle, Richard J. Binney, Salvatore Spina, Suzee E. Lee, Joel H. Kramer, Bruce L. Miller, Howard J. Rosen, Adam L. Boxer, William W. Seeley
Published 2017-01-01

Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

by Xu Chen, Yaqiao Li, Chao Wang, Yinyan Tang, Sue-Ann Mok, Richard M. Tsai, Julio C. Rojas, Anna Karydas, Bruce L. Miller, Adam L. Boxer, Jason E. Gestwicki, Michelle Arkin, Ana Maria Cuervo, Li Gan
Published 2020-01-01

An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy.

by Yun Li, Jason A Chen, Renee L Sears, Fuying Gao, Eric D Klein, Anna Karydas, Michael D Geschwind, Howard J Rosen, Adam L Boxer, Weilong Guo, Matteo Pellegrini, Steve Horvath, Bruce L Miller, Daniel H Geschwind, Giovanni Coppola
Published 2014-03-01

Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy

by Daniel W. Sirkis, Caroline Warly Solsberg, Taylor P. Johnson, Luke W. Bonham, Virginia E. Sturm, Suzee E. Lee, Katherine P. Rankin, Howard J. Rosen, Adam L. Boxer, William W. Seeley, Bruce L. Miller, Ethan G. Geier, Jennifer S. Yokoyama
Published 2023-07-01

Regional correlations between [11C]PIB PET and post-mortem burden of amyloid-beta pathology in a diverse neuropathological cohort

by Sang Won Seo, Nagehan Ayakta, Lea T. Grinberg, Sylvia Villeneuve, Manja Lehmann, Bruce Reed, Charles DeCarli, Bruce L. Miller, Howard J. Rosen, Adam L. Boxer, James P. O’Neil, Lee-Way Jin, William W. Seeley, William J. Jagust, Gil D. Rabinovici
Published 2017-01-01

Progression of Microstructural Degeneration in Progressive Supranuclear Palsy and Corticobasal Syndrome: A Longitudinal Diffusion Tensor Imaging Study.

by Yu Zhang, Rudolph Walter, Peter Ng, Phi N Luong, Shubir Dutt, Hilary Heuer, Julio C Rojas-Rodriguez, Richard Tsai, Irene Litvan, Bradford C Dickerson, Maria Carmela Tartaglia, Gil Rabinovici, Bruce L Miller, Howard J Rosen, Norbert Schuff, Adam L Boxer
Published 2016-01-01

Detection of emerging neurodegeneration using Bayesian linear mixed-effect modeling

by Yann Cobigo, Matthew S. Goh, Amy Wolf, Adam M. Staffaroni, John Kornak, Bruce L. Miller, Gil D. Rabinovici, William W. Seeley, Salvatore Spina, Adam L. Boxer, Bradley F. Boeve, Lei Wang, Ricardo Allegri, Marty Farlow, Hiroshi Mori, Richard J. Perrin, Joel Kramer, Howard J. Rosen
Published 2022-01-01

Peripheral Innate Immune Activation Correlates With Disease Severity in GRN Haploinsufficiency

by Peter A. Ljubenkov, Zachary Miller, Paige Mumford, Jane Zhang, Isabel Elaine Allen, Laura Mitic, Laura Mitic, Adam Staffaroni, Hilary Heuer, Julio C. Rojas, Yann Cobigo, Anna Karydas, Rodney Pearlman, Bruce Miller, Joel H. Kramer, Michael S. McGrath, Michael S. McGrath, Howard J. Rosen, Adam L. Boxer
Published 2019-09-01

Uniform data set language measures for bvFTD and PPA diagnosis and monitoring

by Adam M. Staffaroni, Sandra Weintraub, Katya Rascovsky, Katherine P. Rankin, Jack Taylor, Julie A. Fields, Kaitlin B. Casaletto, Argye E. Hillis, Sladjana Lukic, Maria Luisa Gorno‐Tempini, Hilary Heuer, Merilee A. Teylan, Walter A. Kukull, Bruce L. Miller, Bradley F. Boeve, Howard J. Rosen, Adam L. Boxer, Joel H. Kramer
Published 2021-01-01

Head-to-head comparison between plasma p-tau217 and flortaucipir-PET in amyloid-positive patients with cognitive impairment

by Nidhi S. Mundada, Julio C. Rojas, Lawren Vandevrede, Elisabeth H. Thijssen, Leonardo Iaccarino, Obiora C. Okoye, Ranjani Shankar, David N. Soleimani-Meigooni, Argentina L. Lago, Bruce L. Miller, Charlotte E. Teunissen, Hillary Heuer, Howie J. Rosen, Jeffrey L. Dage, William J. Jagust, Gil D. Rabinovici, Adam L. Boxer, Renaud La Joie
Published 2023-09-01

Local and distant relationships between amyloid, tau and neurodegeneration in Alzheimer's Disease

by Leonardo Iaccarino, Gautam Tammewar, Nagehan Ayakta, Suzanne L. Baker, Alexandre Bejanin, Adam L. Boxer, Maria Luisa Gorno-Tempini, Mustafa Janabi, Joel H. Kramer, Andreas Lazaris, Samuel N. Lockhart, Bruce L. Miller, Zachary A. Miller, James P. O'Neil, Rik Ossenkoppele, Howard J. Rosen, Daniel R. Schonhaut, William J. Jagust, Gil D. Rabinovici
Published 2018-01-01

Sensitivity of the African neuropsychology battery memory subtests and learning slopes in discriminating APOE 4 and amyloid pathology in adult individuals in the Democratic Republi...

by Jean Ikanga, Jean Ikanga, Sarah D. Patrick, Megan Schwinne, Saranya Sundaram Patel, Emmanuel Epenge, Guy Gikelekele, Nathan Tshengele, Immaculee Kavugho, Samuel Mampunza, Kevin E. Yarasheski, Charlotte E. Teunissen, Anthony Stringer, Allan Levey, Julio C. Rojas, Brandon Chan, Argentina Lario Lago, Joel H. Kramer, Adam L. Boxer, Andreas Jeromin, Alvaro Alonso, Robert J. Spencer
Published 2024-03-01

Thalamo-cortical network hyperconnectivity in preclinical progranulin mutation carriers

by Suzee E. Lee, Ana C. Sias, Eena L. Kosik, Taru M. Flagan, Jersey Deng, Stephanie A. Chu, Jesse A. Brown, Anna A. Vidovszky, Eliana Marisa Ramos, Maria Luisa Gorno-Tempini, Anna M. Karydas, Giovanni Coppola, Daniel H. Geschwind, Rosa Rademakers, Bradley F. Boeve, Adam L. Boxer, Howard J. Rosen, Bruce L. Miller, William W. Seeley
Published 2019-01-01

Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases

by Jason A. Chen, Zhongbo Chen, Hyejung Won, Alden Y. Huang, Jennifer K. Lowe, Kevin Wojta, Jennifer S. Yokoyama, Gilbert Bensimon, P. Nigel Leigh, Christine Payan, Aleksey Shatunov, Ashley R. Jones, Cathryn M. Lewis, Panagiotis Deloukas, Philippe Amouyel, Christophe Tzourio, Jean-Francois Dartigues, Albert Ludolph, Adam L. Boxer, Jeff M. Bronstein, Ammar Al-Chalabi, Daniel H. Geschwind, Giovanni Coppola
Published 2018-08-01

18F-flortaucipir (AV-1451) tau PET in frontotemporal dementia syndromes

by Richard M. Tsai, Alexandre Bejanin, Orit Lesman-Segev, Renaud LaJoie, Adrienne Visani, Viktoriya Bourakova, James P. O’Neil, Mustafa Janabi, Suzanne Baker, Suzee E. Lee, David C. Perry, Lynn Bajorek, Anna Karydas, Salvatore Spina, Lea T. Grinberg, William W. Seeley, Eliana M. Ramos, Giovanni Coppola, Maria Luisa Gorno-Tempini, Bruce L. Miller, Howard J. Rosen, William Jagust, Adam L. Boxer, Gil D. Rabinovici
Published 2019-01-01