Identification of Clinically Relevant Subgroups of Chronic Lymphocytic Leukemia Through Discovery of Abnormal Molecular Pathways

by Petr Taus, Sarka Pospisilova, Sarka Pospisilova, Sarka Pospisilova, Karla Plevova, Karla Plevova, Karla Plevova
Published 2021-06-01

Binding of histone H1 to DNA is differentially modulated by redox state of HMGB1.

by Eva Polanská, Šárka Pospíšilová, Michal Štros
Published 2014-01-01

Histone H1 Differentially Inhibits DNA Bending by Reduced and Oxidized HMGB1 Protein.

by Michal Štros, Eva Polanská, Martin Kučírek, Šárka Pospíšilová
Published 2015-01-01

Telomere dynamics in adult hematological malignancies

by Helena Olbertova, Karla Plevova, Kamila Stranska, Sarka Pospisilova
Published 2019-02-01

Bioinformatic strategies for the analysis of genomic aberrations detected by targeted NGS panels with clinical application

by Jakub Hynst, Veronika Navrkalova, Karol Pal, Sarka Pospisilova
Published 2021-03-01

The Role of Oncogenic Tyrosine Kinase NPM-ALK in Genomic Instability

by Cosimo Lobello, Vasilis Bikos, Andrea Janikova, Sarka Pospisilova
Published 2018-03-01

Oxidative stress as a therapeutic perspective for ATM-deficient chronic lymphocytic leukemia patients

by Veronika Navrkalova, Leona Raskova Kafkova, Vladimir Divoky, Sarka Pospisilova
Published 2015-08-01

MicroRNA-210 expression during childbirth and postpartum as a potential biomarker of acute fetal hypoxia

by Barbara Vonkova, Ivona Blahakova, Lukas Hruban, Petr Janku, Sarka Pospisilova
Published 2019-09-01

Bioinformatic pipelines for whole transcriptome sequencing data exploitation in leukemia patients with complex structural variants

by Jakub Hynst, Karla Plevova, Lenka Radova, Vojtech Bystry, Karol Pal, Sarka Pospisilova
Published 2019-06-01

Dynamic miRNA changes during the process of epileptogenesis in an infantile and adult-onset model

by Petra Bencurova, Jiri Baloun, Jakub Hynst, Jan Oppelt, Hana Kubova, Sarka Pospisilova, Milan Brazdil
Published 2021-05-01

Novel genetic variant of HPS1 gene in Hermansky-Pudlak syndrome with fulminant progression of pulmonary fibrosis: a case report

by Martina Doubková, Jakub Trizuljak, Zuzana Vrzalová, Anna Hrazdirová, Ivona Blaháková, Lenka Radová, Šárka Pospíšilová, Michael Doubek
Published 2019-10-01

TP53 aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics

by Elias Campo, Florence Cymbalista, Paolo Ghia, Ulrich Jäger, Sarka Pospisilova, Richard Rosenquist, Anna Schuh, Stephan Stilgenbauer
Published 2018-12-01

RGDS-Modified Superporous Poly(2-Hydroxyethyl Methacrylate)-Based Scaffolds as 3D In Vitro Leukemia Model

by Hana Svozilová, Zdeněk Plichta, Vladimír Proks, Radana Studená, Jiří Baloun, Michael Doubek, Šárka Pospíšilová, Daniel Horák
Published 2021-02-01

Two Novel Mutations in the <i>JAG1</i> Gene in Pediatric Patients with Alagille Syndrome: The First Case Series in Czech Republic

by Dagmar Procházková, Romana Borská, Lenka Fajkusová, Petra Konečná, Eliška Hloušková, Zdeněk Pavlovský, Ondřej Slabý, Šárka Pospíšilová
Published 2021-05-01

Consensus-Based Pharmacophore Mapping for New Set of <i>N</i>-(disubstituted-phenyl)-3-hydroxyl-naphthalene-2-carboxamides

by Andrzej Bak, Jiri Kos, Hana Michnova, Tomas Gonec, Sarka Pospisilova, Violetta Kozik, Alois Cizek, Adam Smolinski, Josef Jampilek
Published 2020-09-01

Dibasic Derivatives of Phenylcarbamic Acid as Prospective Antibacterial Agents Interacting with Cytoplasmic Membrane

by Šárka Pospíšilová, Ivan Malík, Kristyna Bezouskova, Tereza Kauerova, Peter Kollar, Jozef Csöllei, Michal Oravec, Alois Cizek, Josef Jampilek
Published 2020-02-01

ToTem: a tool for variant calling pipeline optimization

by Nikola Tom, Ondrej Tom, Jitka Malcikova, Sarka Pavlova, Blanka Kubesova, Tobias Rausch, Miroslav Kolarik, Vladimir Benes, Vojtech Bystry, Sarka Pospisilova
Published 2018-06-01

The Structure–Antimicrobial Activity Relationships of a Promising Class of the Compounds Containing the N-Arylpiperazine Scaffold

by Ivan Malík, Jozef Csöllei, Josef Jampílek, Lukáš Stanzel, Iveta Zadražilová, Jan Hošek, Šárka Pospíšilová, Alois Čížek, Aidan Coffey, Jim O’Mahony
Published 2016-09-01

Multiple productive immunoglobulin heavy chain gene rearrangements in chronic lymphocytic leukemia are mostly derived from independent clones

by Karla Plevova, Hana Skuhrova Francova, Katerina Burckova, Yvona Brychtova, Michael Doubek, Sarka Pavlova, Jitka Malcikova, Jiri Mayer, Boris Tichy, Sarka Pospisilova
Published 2014-02-01

Epilepsy miRNA Profile Depends on the Age of Onset in Humans and Rats

by Jiri Baloun, Petra Bencurova, Petra Bencurova, Tereza Totkova, Hana Kubova, Marketa Hermanova, Michal Hendrych, Martin Pail, Sarka Pospisilova, Milan Brazdil, Milan Brazdil
Published 2020-09-01