eprintid: 8491 rev_number: 2 eprint_status: archive userid: 1 dir: disk0/00/00/84/91 datestamp: 2023-11-09 16:20:24 lastmod: 2023-11-09 16:20:24 status_changed: 2023-11-09 16:12:47 type: article metadata_visibility: show creators_name: Shah, S.A.A. creators_name: Tang, T.B. creators_name: Faye, I. creators_name: Laude, A. title: Blood vessel segmentation in color fundus images based on regional and Hessian features ispublished: pub keywords: accuracy; algorithm; Article; eye fundus; filter; image analysis; image processing; priority journal; retina blood vessel; retina disease; sensitivity analysis; algorithm; factual database; human; pathology; procedures; retina blood vessel; retina disease; visual system examination, Algorithms; Databases, Factual; Diagnostic Techniques, Ophthalmological; Fundus Oculi; Humans; Image Processing, Computer-Assisted; Retinal Diseases; Retinal Vessels note: cited By 33 abstract: Purpose: To propose a new algorithm of blood vessel segmentation based on regional and Hessian features for image analysis in retinal abnormality diagnosis. Methods: Firstly, color fundus images from the publicly available database DRIVE were converted from RGB to grayscale. To enhance the contrast of the dark objects (blood vessels) against the background, the dot product of the grayscale image with itself was generated. To rectify the variation in contrast, we used a 5 � 5 window filter on each pixel. Based on 5 regional features, 1 intensity feature and 2 Hessian features per scale using 9 scales, we extracted a total of 24 features. A linear minimum squared error (LMSE) classifier was trained to classify each pixel into a vessel or non-vessel pixel. Results: The DRIVE dataset provided 20 training and 20 test color fundus images. The proposed algorithm achieves a sensitivity of 72.05 with 94.79 accuracy. Conclusions: Our proposed algorithm achieved higher accuracy (0.9206) at the peripapillary region, where the ocular manifestations in the microvasculature due to glaucoma, central retinal vein occlusion, etc. are most obvious. This supports the proposed algorithm as a strong candidate for automated vessel segmentation. © 2017, Springer-Verlag Berlin Heidelberg. date: 2017 publisher: Springer Verlag official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85018747145&doi=10.1007%2fs00417-017-3677-y&partnerID=40&md5=3eb38d771822d5839d43f81c42897735 id_number: 10.1007/s00417-017-3677-y full_text_status: none publication: Graefe's Archive for Clinical and Experimental Ophthalmology volume: 255 number: 8 pagerange: 1525-1533 refereed: TRUE issn: 0721832X citation: Shah, S.A.A. and Tang, T.B. and Faye, I. and Laude, A. (2017) Blood vessel segmentation in color fundus images based on regional and Hessian features. Graefe's Archive for Clinical and Experimental Ophthalmology, 255 (8). pp. 1525-1533. ISSN 0721832X