eprintid: 8484
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/00/84/84
datestamp: 2023-11-09 16:20:23
lastmod: 2023-11-09 16:20:23
status_changed: 2023-11-09 16:12:45
type: article
metadata_visibility: show
creators_name: Shukla, V.
creators_name: Hussin, F.A.
creators_name: Hamid, N.H.
creators_name: Ali, N.B.Z.
title: Advances in testing techniques for digital microfluidic biochips
ispublished: pub
keywords: Bioassay; Diagnosis; Digital microfluidics; Drop formation; Drops; Electrodes; Medical applications; Microarrays; Microfluidics; Molecules; Reliability; Testing, Digital microfluidic biochips; Digital microfluidics technology; Droplet manipulation; Electronic domains; MEDA; Microfluidics biochips; Testing technique; Testing technology, Biochips, electrode; human; microarray analysis; microfluidic analysis; microfluidics; reproducibility, Electrodes; Humans; Microarray Analysis; Microfluidic Analytical Techniques; Microfluidics; Reproducibility of Results
note: cited By 13
abstract: With the advancement of digital microfluidics technology, applications such as on-chip DNA analysis, point of care diagnosis and automated drug discovery are common nowadays. The use of Digital Microfluidics Biochips (DMFBs) in disease assessment and recognition of target molecules had become popular during the past few years. The reliability of these DMFBs is crucial when they are used in various medical applications. Errors found in these biochips are mainly due to the defects developed during droplet manipulation, chip degradation and inaccuracies in the bio-assay experiments. The recently proposed Micro-electrode-dot Array (MEDA)-based DMFBs involve both fluidic and electronic domains in the micro-electrode cell. Thus, the testing techniques for these biochips should be revised in order to ensure proper functionality. This paper describes recent advances in the testing technologies for digital microfluidics biochips, which would serve as a useful platform for developing revised/new testing techniques for MEDA-based biochips. Therefore, the relevancy of these techniques with respect to testing of MEDA-based biochips is analyzed in order to exploit the full potential of these biochips. © 2017 by the authors. Licensee MDPI, Basel, Switzerland.
date: 2017
publisher: MDPI AG
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85026655135&doi=10.3390%2fs17081719&partnerID=40&md5=ae9202d528579490d563c7f50d9e627d
id_number: 10.3390/s17081719
full_text_status: none
publication: Sensors (Switzerland)
volume: 17
number: 8
refereed: TRUE
issn: 14248220
citation:   Shukla, V. and Hussin, F.A. and Hamid, N.H. and Ali, N.B.Z.  (2017) Advances in testing techniques for digital microfluidic biochips.  Sensors (Switzerland), 17 (8).   ISSN 14248220