TY  - JOUR
EP  - 4431
SN  - 00263672
PB  - Springer-Verlag Wien
SP  - 4425
TI  - Aptamer-based determination of ATP by using a functionalized impedimetric nanosensor and mediation by a triangular junction transducer
N1  - cited By 10
AV  - none
VL  - 184
UR  - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85028824303&doi=10.1007%2fs00604-017-2485-8&partnerID=40&md5=dbec50d8a23b973c1304c4d9881b80cf
A1  - Gopinath, S.C.B.
A1  - Perumal, V.
A1  - Balakrishnan, S.R.
A1  - Md Arshad, M.K.
A1  - Lakshmipriya, T.
A1  - Haarindraprasad, R.
A1  - Hashim, U.
JF  - Microchimica Acta
Y1  - 2017///
ID  - scholars8195
N2  - The authors describe an impedimetric nanosensor for aptamer-mediated detection of ATP. A triangular junction of polysilicon substrate is used as a transducer. The aptamer was immobilized on the substrate via biotin-streptavidin interaction. ATP can be detected by this method in the 10 to 100 nM concentration range at room temperature and estimated the signal to noise ratio above the range of 3Ï?. It was applied to the detection of ATP in 1:1000 diluted human urine. The desired transducer is highly reproducible and specific. It is selective over closely related molecules such as guanosine triphosphate, cytidine triphosphate and uridine triphosphate. The method is perceived to represent a valuable tool for the diagnosis for infections and inflammations. The novelties shown in this study compared to other sensors are, consumption of low sample volume (~ 1 μl), non-invasive and suitable with AC and DC currents. Figure not available: see fulltext.. © 2017, Springer-Verlag GmbH Austria.
IS  - 11
ER  -