@article{scholars7951, publisher = {Hindawi Limited}, journal = {Oxidative Medicine and Cellular Longevity}, title = {Phytochemicals and Biogenic Metallic Nanoparticles as Anticancer Agents}, note = {cited By 127}, volume = {2016}, year = {2016}, doi = {10.1155/2016/3685671}, abstract = {Cancer is a leading cause of death worldwide. Several classes of drugs are available to treat different types of cancer. Currently, researchers are paying significant attention to the development of drugs at the nanoscale level to increase their target specificity and to reduce their concentrations. Nanotechnology is a promising and growing field with multiple subdisciplines, such as nanostructures, nanomaterials, and nanoparticles. These materials have gained prominence in science due to their size, shape, and potential efficacy. Nanomedicine is an important field involving the use of various types of nanoparticles to treat cancer and cancerous cells. Synthesis of nanoparticles targeting biological pathways has become tremendously prominent due to the higher efficacy and fewer side effects of nanodrugs compared to other commercial cancer drugs. In this review, different medicinal plants and their active compounds, as well as green-synthesized metallic nanoparticles from medicinal plants, are discussed in relation to their anticancer activities. {\^A}{\copyright} 2016 Pasupuleti Visweswara Rao et al.}, url = {https://www.scopus.com/inward/record.uri?eid=2-s2.0-84960977632&doi=10.1155\%2f2016\%2f3685671&partnerID=40&md5=8a835c1fffce863e461c3b2c1afb32e0}, keywords = {Diseases; Drug interactions; Medical nanotechnology; Nanoparticles; Nanostructures; Nanotechnology; Plants (botany), Active compounds; Anti-cancer agents; Anticancer activities; Biological pathways; Medicinal plants; Metallic nanoparticles; Nanoscale levels; Potential efficacy, Synthesis (chemical), antineoplastic agent; cerium oxide nanoparticle; gold nanoparticle; nanoparticle; plant medicinal product; silver nanoparticle; titanium dioxide nanoparticle; ultrasmall superparamagnetic iron oxide; antineoplastic agent; metal nanoparticle; plant medicinal product, antineoplastic activity; Article; cancer therapy; drug mechanism; drug synthesis; green chemistry; human; medicinal plant; nanotechnology; neoplasm; nonhuman; particle size; phase 1 clinical trial (topic); randomized controlled trial (topic); chemistry; nanomedicine; Neoplasms, Antineoplastic Agents; Green Chemistry Technology; Humans; Metal Nanoparticles; Nanomedicine; Neoplasms; Phytochemicals}, author = {Rao, P. V. and Nallappan, D. and Madhavi, K. and Rahman, S. and Jun Wei, L. and Gan, S. H.}, issn = {19420900} }