eprintid: 6590
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/00/65/90
datestamp: 2023-11-09 16:18:23
lastmod: 2023-11-09 16:18:23
status_changed: 2023-11-09 16:07:09
type: conference_item
metadata_visibility: show
creators_name: Jumbri, K.
creators_name: Ahmad, H.
creators_name: Abdulmalek, E.
creators_name: Rahman, M.B.A.
title: Biophysical properties of DNA in hydrated ionic liquids
ispublished: pub
note: cited By 2; Conference of 4th International Conference on Fundamental and Applied Sciences, ICFAS 2016 ; Conference Date: 15 August 2016 Through 17 August 2016; Conference Code:125141
abstract: The biophysical properties and behavior of natural calf thymus DNA in hydrated 1-ethyl-3-butylimidazolium bromide ionic liquid (C2bimBr) have been studied using spectroscopy technique. The effect of ionic liquid concentration and temperature towards the duplex B-DNA conformation were determined. The presence of ionic liquid causes higher duplex DNA stability with the DNA melting temperature of �56°C without any addition of buffer solutions. The electrostatic attraction between ionic liquid's cation and DNA phosphates groups was found play a main role in stabilizing native DNA structure. Understanding of the biophysical properties of DNA in this ionic media could be used as a platform for future development of specific solvent for nucleic acid nanotechnology. © 2016 Author(s).
date: 2016
publisher: American Institute of Physics Inc.
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85006056274&doi=10.1063%2f1.4968137&partnerID=40&md5=79f5dc44cef8ceb3dd6c71b18cd87b6b
id_number: 10.1063/1.4968137
full_text_status: none
publication: AIP Conference Proceedings
volume: 1787
refereed: TRUE
isbn: 9780735414518
issn: 0094243X
citation:   Jumbri, K. and Ahmad, H. and Abdulmalek, E. and Rahman, M.B.A.  (2016) Biophysical properties of DNA in hydrated ionic liquids.  In: UNSPECIFIED.