eprintid: 5297
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/00/52/97
datestamp: 2023-11-09 16:17:01
lastmod: 2023-11-09 16:17:01
status_changed: 2023-11-09 16:01:13
type: article
metadata_visibility: show
creators_name: Malakahmad, A.
creators_name: Abd Manan, T.S.
creators_name: Hilmin, N.
title: Biological procedures to detect carcinogenic compounds in domestic wastewater
ispublished: pub
keywords: bioassay; biological method; cancer; chromosome; domestic waste; mutation; wastewater
note: cited By 2; Conference of 12th International Conference on Modelling, Monitoring and Management of Water Pollution, WP 2014 ; Conference Date: 26 May 2014 Through 28 May 2014; Conference Code:105916
abstract: Cancer is a leading cause of death worldwide and can be increased further to more than 13.1 million people per year by 2030. Cancer occurs due to the continuous exposure of carcinogenic compounds under certain concentrations. A carcinogen is an agent that can cause mutation, leading to cancer. Therefore, mutations are indications of the presence of carcinogenic compounds. The mutation effects in biological organisms are various. They are chromosomal aberrations, growth inhibition and teratogenic effects. These effects can only be detected through the application of biological approaches. This review gives descriptions on the biological detection and measurement of carcinogens in wastewater and water estuaries. The biological procedures such as the chromosomal aberration (CA), Comet assay, Micronucleus (MN) assay SOS chromotest and organic extraction of XAD with blue rayon is discussed. These bioassays played an important role in the detection of carcinogens from waterborne contaminants in the environment such as pesticides, industrial pollution and heavy metals. The evaluations are based on advantages and disadvantages, accuracy, speed and time factor of methods and experimental procedures. As cancer is often linked to DNA damage, these assays are also time and cost effective to estimate the carcinogenic potential of a compound. Thus, the concept of carcinogenic compounds detection and measurement in wastewater is of great attention due to their toxic and non-biodegradable nature. © 2014 WIT Press.
date: 2014
publisher: WITPress
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84903135999&doi=10.2495%2fWP140301&partnerID=40&md5=1b6d30c9d814f1dc67edaa23df7be474
id_number: 10.2495/WP140301
full_text_status: none
publication: WIT Transactions on Ecology and the Environment
volume: 182
place_of_pub: Algarve
pagerange: 345-356
refereed: TRUE
isbn: 9781845647766
issn: 17433541
citation:   Malakahmad, A. and Abd Manan, T.S. and Hilmin, N.  (2014) Biological procedures to detect carcinogenic compounds in domestic wastewater.  WIT Transactions on Ecology and the Environment, 182.  pp. 345-356.  ISSN 17433541