eprintid: 4550
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/00/45/50
datestamp: 2023-11-09 16:16:14
lastmod: 2023-11-09 16:16:14
status_changed: 2023-11-09 15:58:41
type: article
metadata_visibility: show
creators_name: Khan, H.
creators_name: Daraz, N.
creators_name: Khan, M.N.
creators_name: Said, M.
creators_name: Akhtar, N.
creators_name: Badshah, A.
creators_name: Khan, A.S.
creators_name: Ali, M.
title: Synthesis, Structural Characterization, and Evaluation of the Biological Properties of Heteroleptic Palladium(II) Complexes
ispublished: pub
note: cited By 0
abstract: Five heteroleptic palladium(II) complexes of the general formula Pd(PR3)(tu)Cl2, where PR3 = triphenylphosphine (1), diphenyl-o-tolylphosphine (2), diphenyl-p-tolylphosphine (3), diphenyl-t-butylphosphine (4), and diphenyl-o-methoxyphenylphosphine (5), and tu = 1,3-bis(2-methoxyphenyl) thiourea. They all have been synthesized and characterized by various spectroscopic techniques (elemental analysis, FTIR, and 1H NMR and the ligand 1,3-bis(2-methoxyphenyl) thiourea was synthesized by single crystal X-ray diffraction technique). The synthesized compounds were screened for their antibacterial activity against four strains of bacteria (Escherichia coli, Shigella flexneri, Staphylococcus aureus, and Bacillus subtilis). The antitumor potential was evaluated in terms of activity against brine shrimp eggs and DNA interaction. The mixed ligand complexes have exhibited moderate antibacterial activity and promising antitumor potential. © 2014 Hizbullah Khan et al.
date: 2014
publisher: Hindawi Publishing Corporation
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84935845137&doi=10.1155%2f2014%2f916361&partnerID=40&md5=bd37cf222286a396d630df430675f381
id_number: 10.1155/2014/916361
full_text_status: none
publication: Bioinorganic Chemistry and Applications
volume: 2014
refereed: TRUE
issn: 15653633
citation:   Khan, H. and Daraz, N. and Khan, M.N. and Said, M. and Akhtar, N. and Badshah, A. and Khan, A.S. and Ali, M.  (2014) Synthesis, Structural Characterization, and Evaluation of the Biological Properties of Heteroleptic Palladium(II) Complexes.  Bioinorganic Chemistry and Applications, 2014.   ISSN 15653633