relation: https://khub.utp.edu.my/scholars/4550/
title: Synthesis, Structural Characterization, and Evaluation of the Biological Properties of Heteroleptic Palladium(II) Complexes
creator: Khan, H.
creator: Daraz, N.
creator: Khan, M.N.
creator: Said, M.
creator: Akhtar, N.
creator: Badshah, A.
creator: Khan, A.S.
creator: Ali, M.
description: Five heteroleptic palladium(II) complexes of the general formula Pd(PR3)(tu)Cl2, where PR3 = triphenylphosphine (1), diphenyl-o-tolylphosphine (2), diphenyl-p-tolylphosphine (3), diphenyl-t-butylphosphine (4), and diphenyl-o-methoxyphenylphosphine (5), and tu = 1,3-bis(2-methoxyphenyl) thiourea. They all have been synthesized and characterized by various spectroscopic techniques (elemental analysis, FTIR, and 1H NMR and the ligand 1,3-bis(2-methoxyphenyl) thiourea was synthesized by single crystal X-ray diffraction technique). The synthesized compounds were screened for their antibacterial activity against four strains of bacteria (Escherichia coli, Shigella flexneri, Staphylococcus aureus, and Bacillus subtilis). The antitumor potential was evaluated in terms of activity against brine shrimp eggs and DNA interaction. The mixed ligand complexes have exhibited moderate antibacterial activity and promising antitumor potential. © 2014 Hizbullah Khan et al.
publisher: Hindawi Publishing Corporation
date: 2014
type: Article
type: PeerReviewed
identifier:   Khan, H. and Daraz, N. and Khan, M.N. and Said, M. and Akhtar, N. and Badshah, A. and Khan, A.S. and Ali, M.  (2014) Synthesis, Structural Characterization, and Evaluation of the Biological Properties of Heteroleptic Palladium(II) Complexes.  Bioinorganic Chemistry and Applications, 2014.   ISSN 15653633     
relation: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84935845137&doi=10.1155%2f2014%2f916361&partnerID=40&md5=bd37cf222286a396d630df430675f381
relation: 10.1155/2014/916361
identifier: 10.1155/2014/916361