TY - JOUR UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-79959884489&doi=10.1007%2fs11517-011-0734-2&partnerID=40&md5=2ef7bece7037781bf67d9d563d98bc2a TI - Analysis of retinal fundus images for grading of diabetic retinopathy severity SN - 01400118 ID - scholars2072 A1 - Ahmad Fadzil, M.H. A1 - Izhar, L.I. A1 - Nugroho, H. A1 - Nugroho, H.A. Y1 - 2011/// N1 - cited By 57 SP - 693 IS - 6 N2 - Diabetic retinopathy (DR) is a sight threatening complication due to diabetes mellitus that affects the retina. In this article, a computerised DR grading system, which digitally analyses retinal fundus image, is used to measure foveal avascular zone. A v-fold cross-validation method is applied to the FINDeRS database to evaluate the performance of the DR system. It is shown that the system achieved sensitivity of >84, specificity of >97 and accuracy of >95 for all DR stages. At high values of sensitivity (>95), specificity (>97) and accuracy (>98) obtained for No DR and severe NPDR/PDR stages, the computerised DR grading system is suitable for early detection of DR and for effective treatment of severe cases. © 2011 International Federation for Medical and Biological Engineering. VL - 49 JF - Medical and Biological Engineering and Computing AV - none EP - 700 KW - Cross-validation methods; Diabetes mellitus; Diabetic retinopathy; Diabetic retinopathy grading; Early detection; Foveal avascular zones; Fundus image; Grading system; Medical image analysis KW - Grading; Medical imaging; Ophthalmology KW - Eye protection KW - algorithm; article; computer assisted diagnosis; diabetic retinopathy; disease course; evaluation; eye fundus; hospitalization; human; methodology; sensitivity and specificity KW - Algorithms; Diabetic Retinopathy; Disease Progression; Fundus Oculi; Humans; Image Interpretation KW - Computer-Assisted; Sensitivity and Specificity; Severity of Illness Index ER -