relation: https://khub.utp.edu.my/scholars/19815/ title: Ionic liquid-mediated ethosome for transdermal delivery of insulin creator: Nabila, F.H. creator: Islam, R. creator: Shimul, I.M. creator: Moniruzzaman, M. creator: Wakabayashi, R. creator: Kamiya, N. creator: Goto, M. description: Herein, we report ethosome (ET) formulations composed of a safe amount of 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC)-based ionic liquid with various concentrations of ethanol as a carrier for the transdermal delivery of a high molecular weight drug, insulin. The Insulin-loaded ET vesicles exhibited long-term stability compared to conventional DMPC ETs, showing significantly higher drug encapsulation efficiency and increased skin permeation ability. © 2024 The Royal Society of Chemistry. publisher: Royal Society of Chemistry date: 2024 type: Article type: PeerReviewed identifier: Nabila, F.H. and Islam, R. and Shimul, I.M. and Moniruzzaman, M. and Wakabayashi, R. and Kamiya, N. and Goto, M. (2024) Ionic liquid-mediated ethosome for transdermal delivery of insulin. Chemical Communications, 60 (30). pp. 4036-4039. ISSN 13597345 relation: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85187572294&doi=10.1039%2fd3cc06130b&partnerID=40&md5=9ee9b5685dd99741d31b962b2e09047c relation: 10.1039/d3cc06130b identifier: 10.1039/d3cc06130b