TY - JOUR N2 - Fruit and vegetable wastes are linked to the depletion of natural resources and can pose serious health and environmental risks (e.g. eutrophication, water and soil pollution, and GHG emissions) if improperly managed. Current waste management practices often fail to recover high-value compounds from fruit wastes. Among emerging valorization methods, the utilization of fruit wastes as a feedstock for microalgal biorefineries is a promising approach for achieving net zero waste and sustainable development goals. This is due to the ability of microalgae to efficiently sequester carbon dioxide through photosynthesis, utilize nutrients in wastewater, grow in facilities located on non-arable land, and produce several commercially valuable compounds with applications in food, biofuels, bioplastics, cosmetics, nutraceuticals, pharmaceutics, and various other industries. However, the application of microalgal biotechnology towards upcycling fruit wastes has yet to be implemented on the industrial scale due to several economic, technical, operational, and regulatory challenges. Here, we identify sources of fruit waste along the food supply chain, evaluate current and emerging fruit waste management practices, describe value-added compounds in fruit wastes, and review current methods of microalgal cultivation using fruit wastes as a fermentation medium. We also propose some novel strategies for the practical implementation of industrial microalgal biorefineries for upcycling fruit waste in the future. © 2024 The Author(s) ID - scholars19578 UR - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85191016195&doi=10.1016%2fj.fochms.2024.100203&partnerID=40&md5=998eff691cf9075ea45cb9f17a48e854 VL - 8 KW - amylose; anthocyanin; arachidic acid; aurantiin; biogas; bromelain; caffeic acid; carotenoid; catechin; cellulase; chlorogenic acid; citrulline; docosahexaenoic acid; ellagic acid; epicatechin; fertilizer; ferulic acid; flavonoid; flavoring agent; gallic acid; gelling agent; hemicellulose; hesperidin; kaempferol; lignin; lignocellulose; limonene; limonin; linoleic acid; mangiferin; monophenol monooxygenase; nutraceutical; oleic acid; palmitic acid; pectin; phenol; phytosterol; polyphenol; polysaccharide; prebiotic agent; probiotic agent; riboflavin; saponin; sunscreen; ursolic acid KW - anaerobic digestion; animal food; antibacterial activity; antioxidant activity; Article; atherosclerosis; bioenergy; biofilm; biofuel production; biomass; biotechnology; biotransformation; catering service; chemical oxygen demand; Chlamydomonas reinhardtii; cider; climate change; coculture; colorectal cancer; composting; cost effectiveness analysis; drug cost; drug delivery system; electron transport; encapsulation; environmental risk; eutrophication; fermentation; food industry; food intake; food packaging; food processing; food waste; freeze drying; fruit; fruit and vegetable waste; greenhouse effect; greenhouse gas emission; health care cost; hypertension; lipid storage; liver toxicity; microalga; mixotroph; municipal solid waste; nanoemulsion; nonhuman; nutrient; obesity; patent; photolysis; photosynthesis; physical chemistry; pollution; quality of life; RNA interference; sanitation; seasonal variation; socioeconomics; soil pollution; solid waste management; suspended particulate matter; sustainable development goal; valorization; waste; waste management; waste water management; wastewater; watermelon; white wine; wound healing A1 - Lee, A. A1 - Lan, J.C.-W. A1 - Jambrak, A.R. A1 - Chang, J.-S. A1 - Lim, J.W. A1 - Khoo, K.S. JF - Food Chemistry: Molecular Sciences N1 - cited By 0 AV - none Y1 - 2024/// TI - Upcycling fruit waste into microalgae biotechnology: Perspective views and way forward ER -