TY  - CONF
AV  - none
N2  - Multiple sclerosis (MS) is a type of auto-immune disease affecting the human brain. One of the challenges in clinical diagnosis of MS lies in its close similarity to another type of brain auto-immune disease known as neuromyelitis optica (MNO). Hence, various researchers are looking into the development of computer-aided differential diagnosis (CADD) of MS vs. MNO. Generally, the development of the CADD, involves image pre-processing, feature extraction, statistical analysis and training and testing of the classification model. The focus of this paper is on the 2 critical pre-processing steps prior to classification of MS vs. MNO, namely skull stripping and lesion segmentation. In particular, both skull stripping and brain lesion segmentation are tested with a popular semantic segmentation technique, DeepLabV3. For comparison, a recently published technique, SynthStrip from FreeSurfer 1, developed by Harvard University is also tested for brain extraction / skull removal. Similarly for segmentation of brain lesions, Lesion Segmentation Tool in SPM Toolbox is tested and compared. The results from this study provides insight on what are the appropriate pre-processing techniques for the development of an reliable automatic differential diagnosis tool for multiple sclerosis conditions. © 2023 IEEE.
N1  - cited By 1; Conference of 2nd IEEE International Conference on Vision Towards Emerging Trends in Communication and Networking Technologies, ViTECoN 2023 ; Conference Date: 5 May 2023 Through 6 May 2023; Conference Code:190031
KW  - Extraction; Magnetic resonance imaging; Medical imaging; Semantic Segmentation; Semantics
KW  -  Brain MRI; Computer-aided; Deeplabv3; Differential diagnosis; Image preprocessing; Lesion segmentations; Multiple sclerosis; Neurological disorders; Neuromyelitis optica; Skull stripping
KW  -  Computer aided diagnosis
ID  - scholars19190
TI  - Image Pre-processing for Differential Diagnosis of Multiple Sclerosis using Brain MRI
Y1  - 2023///
UR  - https://www.scopus.com/inward/record.uri?eid=2-s2.0-85165540084&doi=10.1109%2fViTECoN58111.2023.10157177&partnerID=40&md5=863911fa4df8cc4a4157ad4592ea2650
A1  - Memon, K.
A1  - Yahya, N.
A1  - Yusoff, M.Z.
A1  - Hashim, H.
A1  - Ali, S.S.A.
A1  - Siddiqui, S.
ER  -