eprintid: 18991
rev_number: 2
eprint_status: archive
userid: 1
dir: disk0/00/01/89/91
datestamp: 2024-06-04 14:11:26
lastmod: 2024-06-04 14:11:26
status_changed: 2024-06-04 14:04:35
type: conference_item
metadata_visibility: show
creators_name: Nuge, T.
creators_name: Singh, J.K.A.-P.R.
creators_name: Al-Dhahebi, A.M.M.
creators_name: Yusuf, N.R.
creators_name: Zaki, Y.H.
creators_name: Saheed, M.S.M.
title: Electrospun PCL/TPU/CA based nanocomposite for potential use as implants in tympanic membrane (TM) repair
ispublished: pub
keywords: Biomechanics; Electrospinning; Tissue; Tissue regeneration, Acetate concentrations; Cellulose acetates; Electrospinning process; Electrospuns; Hydrophilics; Minimum requirements; Physicomechanical properties; Property; Soft tissue; Tympanic membranes, Nanocomposites, Adjustment; Cellulose Acetate; Cellulose Wadding; Interest; Maintenance; Processes; Work
note: cited By 0; Conference of 2023 IEEE International Conference on Sensors and Nanotechnology, SENNANO 2023 ; Conference Date: 26 September 2023 Through 27 September 2023; Conference Code:195657
abstract: Electrospun nanocomposites have received great deals of interest for soft tissue engineered implants including tympanic membrane TM repaired. In this work, an innovative PCL/TPU/CA nanocomposite were fabricated via the electrospinning technology. The physico-mechanical properties of the nanocomposites exhibit favorable properties for tissue regeneration. This work has shown that the properties of the nanocomposite can be tuning to desirable properties that mimics the human TM by adjusting the cellulose acetate (CA) concentration during the electrospinning process. The elastic modulus of the nanocomposite has increased to 130 MPa after addition 30  of CA, which meet the minimum requirement for human TM at 45 MPa. Highly porous and hydrophilic in nature of the nanocomposites make them a very good candidate to be considered for chronic tympanic membrane repair as these surface properties are anticipated to facilitate cell migration and proliferation in tissue regeneration. © 2023 IEEE.
date: 2023
publisher: Institute of Electrical and Electronics Engineers Inc.
official_url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85182732230&doi=10.1109%2fSENNANO57767.2023.10352530&partnerID=40&md5=f14e1b2138f0ef181ffe9af4525cb3c4
id_number: 10.1109/SENNANO57767.2023.10352530
full_text_status: none
publication: 2023 IEEE International Conference on Sensors and Nanotechnology, SENNANO 2023
pagerange: 241-244
refereed: TRUE
isbn: 9798350333312
citation:   Nuge, T. and Singh, J.K.A.-P.R. and Al-Dhahebi, A.M.M. and Yusuf, N.R. and Zaki, Y.H. and Saheed, M.S.M.  (2023) Electrospun PCL/TPU/CA based nanocomposite for potential use as implants in tympanic membrane (TM) repair.  In: UNSPECIFIED.